Ornidazole Sodium Chloride Injection

This product is a third-generation nitroimidazole derivative. The mechanism by which it exerts its antimicrobial effect may be: through the nitro group in its molecule, it is reduced to an amino group in an anaerobic environment or through the formation of free radicals, which interacts with cell components and causes the death of microorganisms.

Ornidazole. Chemical name: 1-(3-chloro-2-hydropropyl)-2-methyl-5-nitroimidazole.

This product is a colorless or almost colorless clear liquid.

1. It is used to treat various infectious diseases caused by sensitive anaerobic bacteria such as Bacteroides fragilis, Bacteroides dissimilar, Bacteroides ovale, Bacteroides thetaiotaomicron, Bacteroides vulgaris, Clostridium, Eubacterium, Peptococcus and Peptostreptococcus, Helicobacter pylori, Bacteroides melanin, Fusobacterium, Co-phaga, Bacteroides gingivalis, etc., including: (1) abdominal infection: mesangitis, intra-abdominal abscess, liver abscess, etc.; (2) pelvic infection: endometritis, myometritis, fallopian tube or ovarian abscess, pelvic soft tissue infection, Haemophilus vaginitis, etc.; (3) oral infection: periodontitis, apical periodontitis, pericoronitis, acute ulcerative gingivitis, etc.; (4) surgical infection: wound infection, epidermal abscess, bedsore ulcer infection, cellulitis, gas gangrene, etc.; (5) brain infection: meningitis, cerebral

Intravenous drip, each bottle (100ml, concentration is 5mg/ml) drip time is not less than 30 minutes. Dosage: 1. Post-operative prevention of infection caused by anaerobic bacteria: 1g of ornidazole is dripped once before surgery. 2. Treatment of infection caused by anaerobic bacteria: The first dose of intravenous drip is 0.5-1g, and then 0.5g is dripped every 12 hours for 5-10 days; children are dripped every 12 hours at a dose of 10mg/kg. For infection caused by anaerobic bacteria, if the patient's symptoms improve, it is recommended to switch to oral preparations. 3. For the treatment of severe amoebic dysentery or amoebic abscess, the initial dose is 0.5-1g, and then 0.5g is dripped every 12 hours for 3-6 days. Children are dripped daily at a dose of 20-30mg/kg.

This product is usually well tolerated. The following reactions may occur during medication: 1. Digestive system: including mild stomach discomfort, nausea, bad breath, etc.; 2. Nervous system: including dizziness, drowsiness, vertigo, etc.; 3. Allergic reactions: such as rash, pruritus, etc.; 4. Others: leukopenia, etc.

1. It is contraindicated for patients who are allergic to nitroimidazole drugs; 2. It is contraindicated for patients with brain and spinal cord lesions and epilepsy; 3. It is contraindicated for patients with organ sclerosis, low hematopoietic function and chronic alcoholism.

Precautions for children: Use with caution in children. It is not recommended for children under 3 years old. Precautions for pregnancy and lactation: Use with caution in early pregnancy (first three months of pregnancy) and lactating women. Precautions for the elderly: Use the same medication as adults.

1. Compared with other nitroimidazole drugs, this product has no inhibitory effect on acetaldehyde dehydrogenase. 2. Ornidazole can inhibit the metabolism of the anticoagulant warfarin, prolong its half-life, and enhance the efficacy of the anticoagulant. When used with warfarin, the prothrombin time should be observed and the dosage should be adjusted. 3. Since this product has many contraindications, it should be administered alone.

Keep away from light, tightly closed, in a cool and dark place.

100ml: Ornidazole 0.5g and sodium chloride 0.9g

18 months

Xi'an Wan Long Pharmaceutical Co., Ltd.

• Founded in:

  1995-05-26

• Address:

  No. 5, Chuangxin Road, New Industrial Park, Xi'an High-tech Zone

• Tax NO.:

  91610131294460976R

• Registered Funds:

  75 million yuan

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