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Sparfloxacin Lactate Tablets

Function and Efficacy

This product is a quinolone antibacterial drug. It is a broad-spectrum antibacterial drug. It has obvious antibacterial effects on Gram-positive bacteria including Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes, Streptococcus pneumoniae, and Enterococcus faecalis; it also has good antibacterial effects on Gram-negative bacteria Escherichia coli, Klebsiella, Salmonella, Shigella, Vibrio parahaemolyticus, Proteus, Enterobacter, Pseudomonas, Acinetobacter, Neisseria (Neisseria gonorrhoeae, etc.). This product also has good antibacterial effects on mycoplasma, chlamydia, Legionella, anaerobic bacteria including Bacteroides fragilis and Mycobacterium. The mechanism of action of this product is to inhibit the action of DNA gyrase in the process of bacterial DNA synthesis and play a bactericidal role.

Ingredients

Sparfloxacin lactate.

Appearance

This product is yellow or light yellow tablets.

Indication

This product can be used for mild and moderate infections caused by sensitive bacteria, including: 1. Respiratory system infections: such as acute pharyngitis, acute tonsillitis, otitis media, <Aclass=bluehref=http://jbk.39.net

Usage and Dosage

For adults, take orally 0.1-0.3g at a time, not more than 0.4g at most, once a day. The course of treatment is generally 5-10 days. The course of treatment can be appropriately increased or decreased according to the type of disease and condition.

Adverse Reactions

1. Digestive system reactions: such as nausea, vomiting, lack of appetite, upper abdominal discomfort, soft stools, diarrhea, abdominal distension, constipation, bloody stools, stomatitis, etc. 2. Allergic reactions: such as rash, fever, local redness, edema, itching, blisters, erythema, photosensitivity reaction, congestion, etc. 3. Central nervous system: headache, dizziness, irritability, insomnia, cramps, tremors, etc. 4. Laboratory tests: GOT, GPT, ALP, LDH, BUN, γ-CTP, serum creatinine and total bilirubin increased, and may also cause eosinophilia and decreased white blood cells, red blood cells, hemoglobin and platelets; there are reports of mild QT prolongation abroad. 5. Others: occasionally tendinitis, pseudomembranous colitis, interstitial pneumonia, shock, allergic syndrome (dyspnea, edema, hoarseness, flushing, pruritus, etc.), eye mucosal syndrome (Stevens-Johnson syndrome), hypoglycemia, numbness, discomfort, fatigue, etc.

Precautions

It is contraindicated for patients who are allergic to quinolones, pregnant women, lactating women, and patients under 18 years of age.

Special Population Medication

Precautions for children: The safety and effectiveness of this product for patients under 18 years of age have not been established, so it is contraindicated. Precautions for pregnancy and lactation: Fluoroquinolones can pass through the blood-placental barrier and can be secreted into breast milk. Their concentration is close to the blood concentration. Precautions for pregnant and lactating women: This product is contraindicated. Precautions for the elderly: This product should be used with caution by the elderly. If used, the dosage should be appropriately reduced.

Drug Interactions

1. Like enoxacin, norfloxacin and ciprofloxacin, there are rare reports of spasms when this product is used in combination with non-steroidal anti-inflammatory drugs (such as fenbutyric acid, propionic acid derivatives, etc.). 2. When this product is used in combination with antacids containing aluminum, magnesium, iron and sucralfate, it can reduce the absorption of this product, thereby reducing the efficacy. If it is necessary to take it, it should be taken at an interval of 4 hours. 3. When this product is used in combination with theophylline, caffeine, warfarin and cimetidine, it does not affect the plasma concentration of the latter. 4. When it is used in combination with digoxin and probenecid, it does not affect the pharmacokinetics of this product. 5. Nutritional supplements containing metal ions and vitamins containing zinc, iron and calcium can be taken 4 hours after taking this product. 6. This product should not be used in combination with astemizole, terfenadine, cisapride, erythromycin, pentamidine, phenothiazines, tricyclic antidepressants, disopyramide and amiodarone.

Storage

Keep tightly closed.

Packaging Specification

0.1g (as sparfloxacin)

Validity Period

24 months

Manufacturer

Shandong Zibo Xinda Pharmaceutical Co., Ltd.

  • Founded in:

    1993-03-11
  • Address:

    No. 1, Lutai Avenue, Zibo High-tech Zone
  • Tax NO.:

    9137030361328152XT
  • Registered Funds:

    84.93 million yuan
  • Website:

  • Email:

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