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Estradiol Benzoate Injection

Function and Efficacy

Estrogen drugs. They can cause endometrial hyperplasia, enhance uterine smooth muscle contraction, and promote breast development and hyperplasia. Large doses inhibit the release of prolactin, counteract the effects of androgens, and increase calcium deposition in bones.

Ingredients

The main ingredient of this product is estradiol benzoate. Its chemical name is: 3-hydroxyestrone-1,3,5 (10)-triene-17beta;-ol-3-benzoate. Its structural formula is: Molecular formula: C25H28O3 Molecular weight: 376.50

Name Description Content CAS NO. Manufacturer
Estradiol benzoateIngredients

Estrogen drugs. They can cause endometrial hyperplasia, enhance uterine smooth muscle contraction, and promote breast development and hyperplasia. Large doses inhibit the release of prolactin, counteract the effects of androgens, and increase calcium deposition in bones.

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Indication

1. Supplementation of estrogen deficiency, such as atrophic vaginitis, female gonadal dysfunction, vulvar dryness, menopausal vasomotor symptoms, oophorectomy, primary ovarian failure, etc. 2. Advanced prostate cancer (breast cancer, ovarian cancer patients are prohibited). 3. Combined with progesterone drugs, it can inhibit ovulation. 4. Amenorrhea, abnormal menstruation, functional uterine bleeding, uterine dysplasia.

Usage and Dosage

1 For menopausal syndrome, 1-2 mg intramuscularly once, 2-3 times a week. 2 Uterine hypoplasia, 1-2 mg once, intramuscularly once every 2-3 days. 3 Functional uterine bleeding, 1 mg-2 mg intramuscularly daily, reduce the dose as appropriate after the bleeding is clear, and withdraw with progesterone at a later date. 4 Weaning, 2 mg intramuscularly daily, reduce the dose after no more than 3 days or change to a small amount of oral medication until it takes effect.

Adverse Reactions

There may be nausea, headache, breast tenderness, and occasionally thrombosis, rash, water and sodium retention, etc.

Precautions

It is contraindicated for patients with thrombophlebitis, pulmonary embolism, liver and kidney diseases, estrogen-related tumors (such as breast cancer, vaginal cancer, cervical cancer) and pregnant women.

Drug Interactions

When used in combination with hypoglycemic drugs, their hypoglycemic effect may be weakened and the dosage should be adjusted.

Storage

Keep away from light and store in sealed container.

Packaging Specification

1ml:5mg

Manufacturer

Tianjin Pharmaceutical Heping (Tianjin) Pharmaceutical Co., Ltd.

  • Founded in:

    2010-11-12
  • Address:

    No. 221 Huanghai Road, Tianjin Development Zone
  • Tax NO.:

    91120116562691739J
  • Registered Funds:

    604.05 million yuan
  • Website:

  • Email:

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