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Meleumycin Granules

Function and Efficacy

This product is a multi-component macrolide antibiotic produced by Streptomyces. Its antibacterial properties are similar to those of erythromycin. It shows strong antibacterial effects on Gram-positive bacteria and mycoplasmas, and also has antibacterial effects on some Gram-negative bacteria such as Neisseria meningitidis and Neisseria gonorrhoeae. Some erythromycin-resistant Staphylococcus aureus may still be sensitive to this product. This product works by acting on the 50S subunit of bacterial ribosomes and hindering the synthesis of bacterial proteins. It is a growth-stage antibacterial drug.

Ingredients

The main ingredients of this product are midecamycin A1 and kitasamycin A6.

Appearance

This product is white or off-white granules.

Indication

It is mainly suitable for respiratory tract, skin, soft tissue, biliary tract infections and mycoplasma pneumonia caused by sensitive bacteria such as Staphylococcus aureus, hemolytic Streptococcus, Pneumococcus, Corynebacterium diphtheriae and Mycoplasma.

Usage and Dosage

Oral administration: 0.8-1.2 g per day for adults and 30 mg/kg per day for children, divided into 3-4 doses.

Adverse Reactions

1. Hepatotoxicity: At normal doses, the hepatotoxicity of this product is relatively small, mainly manifested as cholestasis and temporary elevation of serum aminotransferase, which can generally be restored after discontinuation of the drug. 2. Allergic reactions: Mainly manifested as drug fever, drug rash and urticaria. 3. Occasionally, gastrointestinal reactions such as nausea, vomiting, upper abdominal discomfort, and loss of appetite may occur.

Precautions

Patients who are allergic to this product and macrolide drugs are contraindicated.

Special Population Medication

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: 1. Some components of Sekil can enter the fetal circulation through the placenta. The concentration is generally not high, and there is no report on the impact on the fetus. However, pregnant women should still weigh the pros and cons when taking Sekil. 2. Some components of Sekil can enter breast milk, so breastfeeding women should weigh the pros and cons when taking Sekil. Precautions for the elderly: Not yet clear.

Drug Interactions

This product can inhibit the normal metabolism of theophylline. When used in combination with theophylline, it can cause an abnormal increase in theophylline blood concentration and lead to poisoning or even death. Therefore, theophylline blood concentration should be monitored when the two drugs are used in combination.

Storage

Sealed, store in a dry place.

Packaging Specification

0.1g (100,000 units)

Validity Period

24 months

Manufacturer

Sichuan Taile Pharmaceutical Co., Ltd.

  • Founded in:

    1999-06-24
  • Address:

    Suining Innovation Industrial Park
  • Tax NO.:

    91510900711818546Q
  • Registered Funds:

    10 million yuan
  • Website:

  • Email:

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