Ranitidine Hydrochloride Tablets
Function and Efficacy
Pharmacology Ranitidine has the effect of competitively blocking the binding of histamine to H2 receptors. It inhibits the effect of gastric acid, which is 5 to 12 times that of cimetidine in terms of moles. Therefore, it is a potent H2 receptor blocker.
Ingredients
Ranitidine
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| RanitidineIngredients |
Competitively blocks the binding of histamine to H2 receptors, inhibits gastric acid secretion, and is 5 to 12 times more potent than cimetidine (in moles) More |
66357-35-5 | 5 |
Appearance
This product is a sugar-coated tablet or a film-coated tablet, which appears off-white or slightly yellow after removing the coating.
Indication
Used to treat duodenal ulcer, gastric ulcer, reflux esophagitis, Zollinger-Ellison syndrome and other high gastric acid secretion diseases.
Usage and Dosage
Oral administration. Adults take 1 tablet at a time, twice a day. Take in the morning and before bedtime.
Adverse Reactions
1. Common symptoms include nausea, rash, constipation, fatigue, headache, dizziness, etc. 2. Compared with cimetidine, the adverse effects of damage to kidney function, gonadal function and central nervous system are milder. 3. A small number of patients suffered mild liver damage after taking the drug, and the symptoms disappeared after stopping the drug, and the liver function returned to normal. It was suspected that it might be a drug allergic reaction and had nothing to do with the dosage of the drug. 4. Long-term use can continuously reduce the acidity of gastric juice, which is conducive to the reproduction of bacteria in the stomach, thereby reducing nitrates in food to nitrites and forming N-nitroso compounds.
Precautions
It is not suitable for children under 8 years old. It is not suitable for pregnant or lactating women.
Special Population Medication
Precautions for children: Children under 8 years old are prohibited. Precautions for pregnancy and lactation: Precautions for pregnant and lactating women. Precautions for the elderly: The liver and kidney functions of the elderly are reduced. To ensure the safety of medication, the dosage should be adjusted.
Drug Interactions
1. When used with warfarin, lidocaine, diazepam, propranolol and other drugs that are metabolized by the liver, the blood concentration of ranitidine will not increase and cause toxic side effects. 2. When used with anticoagulants and anti-epileptic drugs, it is safer than cimetidine. 3. When used with procainamide, the clearance rate of procainamide can be reduced. 4. It can reduce liver blood flow, so when used with propranolol, lidocaine and other drugs whose metabolism is greatly affected by liver blood flow, it can delay the effects of these drugs.
Storage
Keep away from light, sealed and stored in a dry place.
Packaging Specification
0.15g (calculated as C13H22N403S)
Manufacturer
CSPC Zhongnuo PHARMACEUTICAL(Shijiazhuang) Co., Ltd.
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Founded in:
1997-12-12 -
Address:
No. 88, Yangzi Road, Shijiazhuang Economic and Technological Development Zone, Hebei Province -
Tax NO.:
91130100601908022F -
Registered Funds:
678.5559 million yuan -
Website:
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Email: