Gliclazide Tablets (II)

Not yet clear.

Gliclazide.

Flake.

This product is used for type 2 diabetes, especially for those with vascular complications.

Follow the doctor's advice: The usual starting dose is 80 mg 1-2 times a day. Then adjust the dose to 80-240 mg per day based on the results of blood and urine sugar tests. Reduce the dose for elderly patients.

1. Nausea, vomiting, upper abdominal pain, constipation, and diarrhea may occur during medication. Taking the drug during meals can reduce the above adverse reactions. Other adverse reactions include thrombocytopenia, granulocytopenia, anemia, etc., and skin allergies may occur occasionally. 2. Gastrointestinal disorders, including nausea, indigestion, diarrhea, and constipation, have been reported; if gliclazide is taken during meals or the dose is divided into several doses, the above two symptoms can be avoided or alleviated. 3. The following are the less reported adverse reactions: ① Mucosal and skin reactions: rash, pruritus, urticaria, maculopapular rash. ② Blood diseases: anemia, leukopenia, thrombocytopenia. ③ Increased liver enzyme levels (ASAT, ALAT, alkaline phosphatase), hepatitis (rare). If cholestatic jaundice occurs, stop taking the drug. Generally speaking, these symptoms will disappear after treatment is stopped.

The use of this drug is contraindicated in the following cases: 1. Patients who are allergic to gliclazide or any of the excipients used, or to other sulfonylureas or sulfonamides. 2. Patients with insulin-dependent diabetes, especially juvenile diabetes, diabetic patients with ketoacidosis or pre-diabetic coma. 3. Patients with severe liver or kidney dysfunction. 4. Patients treated with miconazole (see [Drug Interactions]). 5. Lactation. 6. Porphyria: Pigments (porphyrins) accumulate in the body. In short, it is not recommended to use this drug with phenylbutazone, danazol (see [Drug Interactions]) or alcohol.

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Not yet clear.

1 The following drugs may increase the risk of hypoglycemia. (1) Concomitant use is prohibited: Miconazole (systemic route, oral gel): increases the hypoglycemic effect and may cause hypoglycemic symptoms and even coma. (2) Concomitant use is not recommended: ① Phenylbutazone (systemic route): increases the hypoglycemic effect of sulfonylureas [replaces their binding to plasma proteins and/or reduces their clearance]. It is best to use an anti-inflammatory drug with few interactions, otherwise, the patient should be warned and the importance of self-monitoring should be emphasized; when used with anti-inflammatory drugs, it is necessary to adjust the drug dosage during treatment and during the treatment interruption stage. ② Alcohol: increases hypoglycemic reactions, especially chlorpropamide, glibenclamide, glipizide, and toluidine (by inhibiting compensatory reactions), and also increases the incidence of hypoglycemic coma.

seal.

80 mg

24 months

BeijingChunfengPharmaceuticals Co., Ltd.

• Founded in:

  2010-02-09

• Address:

  No. 72, Hengli Street, Beifang Town, Huairou District, Beijing

• Tax NO.:

  91110116551441611R

• Registered Funds:

  110 million yuan

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