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Nefopam Hydrochloride Injection

Function and Efficacy

This product is a new type of non-narcotic analgesic, with mild antipyretic and muscle relaxant effects. The chemical structure belongs to cyclized o-methylbenzylamine. Therefore, it does not have the characteristics of non-steroidal anti-inflammatory drugs, nor is it an opioid receptor agonist. It is effective for moderate and severe pain. An intramuscular injection of 20 mg of this product is equivalent to the effect of 12 mg of morphine. It has a mild respiratory depressant effect. It has no inhibitory effect on the circulatory system. There is no tolerance and dependence. Acute toxicity LD50 (mg/kg): mice, oral 66.6; intraperitoneal 28.7; intravenous 21.9. Rats, oral 178; intramuscular injection 56.9.

Ingredients

Nefopam Hydrochloride

Name Description Content CAS NO. Manufacturer
Nefopam hydrochlorideIngredients

This product is a new type of non-narcotic analgesic, with mild antipyretic and muscle relaxant effects. Its chemical structure belongs to cyclized o-methylbenzylamine. Therefore, it does not have the characteristics of non-steroidal anti-inflammatory drugs, nor is it an opioid receptor agonist. It is effective for moderate and severe pain. An intramuscular injection of 20 mg of this product is equivalent to the effect of 12 mg of morphine. It has a mild respiratory depressant effect. It has no depressant effect on the circulatory system. There is no tolerance and dependence.

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23327-57-3 12

Indication

It is used for postoperative analgesia, cancer pain, acute traumatic pain. It is also used for visceral smooth muscle colic such as acute gastritis, biliary ascariasis, ureteral stones, etc. It is also used as an auxiliary drug for local anesthesia, acupuncture anesthesia, etc.

Usage and Dosage

Intramuscular or intravenous injection: 20 mg at a time, or every 3 to 4 hours if necessary.

Adverse Reactions

When the effects occur, there are often drowsiness, nausea, sweating, dizziness, headache, etc. But it usually does not last long. Occasionally, dry mouth, dizziness, and rash are seen.

Precautions

It is contraindicated in patients with severe cardiovascular disease, myocardial infarction or convulsions.

Storage

Keep away from light and store in a sealed container.

Packaging Specification

1ml:20mg

Manufacturer

Shandong Xinhua Pharmaceutical Company Limited

  • Founded in:

    1998-11-20
  • Address:

    Chemical Industry Zone, Zibo High-tech Industrial Development Zone
  • Tax NO.:

    91370300164103727C
  • Registered Funds:

    682,407,635 yuan
  • Website:

  • Email:

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