Ranitidine Hydrochloride Capsules

Ranitidine has the effect of competitively blocking the binding of histamine to H2 receptors. Its inhibitory effect on gastric acid is 5 to 12 times that of cimetidine in terms of moles. Therefore, it is a potent H2 receptor blocker.

The main ingredient of this product and its chemical name are: Ranitidine hydrochloride, and its chemical name is: N-methyl-N-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]-methyl]thio]ethyl]-2-nitro-1,1-ethylenediamine hydrochloride.

This product is a capsule, and its contents are off-white or light yellow powder.

Used to treat duodenal ulcer, gastric ulcer, reflux esophagitis, Zollinger-Ellison syndrome and other high gastric acid secretion diseases.

1. Oral, 150 mg (1 tablet at a time), twice a day, or 300 mg (2 tablets at a time), once before bedtime. 2. Maintenance treatment: Oral, 150 mg (1 tablet at a time), once every night. 3. For patients with severe renal disease, the half-life of ranitidine is prolonged, and the dose should be reduced to 75 mg (half a tablet at a time), twice a day. 4. For the treatment of Zollinger-Ellison syndrome, a large amount of 600-1200 mg per day (4-8 tablets per day) is recommended.

1. Common symptoms include nausea, rash, constipation, fatigue, headache, dizziness, etc. 2. Compared with cimetidine, the adverse effects of damage to kidney function, gonadal function and central nervous system are milder. 3. A small number of patients suffered mild liver damage after taking the drug, and the symptoms disappeared after stopping the drug, and the liver function returned to normal. It was suspected that it might be a drug allergic reaction and had nothing to do with the dosage of the drug. 4. Long-term use can continuously reduce the acidity of gastric juice, which is conducive to the reproduction of bacteria in the stomach, thereby reducing nitrates in food to nitrites and forming N-nitroso compounds.

Not suitable for children under 8 years old; not suitable for pregnant or lactating women.

Precautions for children: Children under 8 years old are prohibited. Precautions for pregnancy and lactation: Precautions for pregnant and lactating women. Precautions for the elderly: The liver and kidney functions of the elderly are reduced. To ensure the safety of medication, the dosage should be adjusted.

1. When used with warfarin, lidocaine, diazepam, propranolol and other drugs that are metabolized by the liver, the blood concentration of ranitidine will not increase and cause toxic side effects. 2. When used with anticoagulants and anti-epileptic drugs, it is safer than cimetidine. 3. When used with procainamide, the clearance rate of procainamide can be reduced. 4. It can reduce liver blood flow, so when used with propranolol, lidocaine and other drugs whose metabolism is greatly affected by liver blood flow, it can delay the effects of these drugs.

Keep away from light, sealed and stored in a dry place.

0.15 g (calculated as C13H22N4O3S)

24 months

Shanghai Modern Hasen (Shangqiu) Pharmaceutical Co., Ltd.

• Founded in:

  1999-11-12

• Address:

  No. 166, North side of Xinxing Road, west side of Zhenxing Road, Liangyuan District, Shangqiu City

• Tax NO.:

  91411400716735619N

• Registered Funds:

  83.29 million yuan

• Website:

  Log in to view

• Email:

  Log in to view