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Bicyclol Tablets

Function and Efficacy

Bicyclol is a derivative of biphenyl structure. Animal test results show that bicyclol has an effect on the increase of aminotransferase in acute liver injury of mice caused by carbon tetrachloride, D-galactosamine, and paracetamol, and the increase and decrease of aminotransferase in immune hepatitis of mice, and the pathological morphological damage of liver tissue is alleviated to varying degrees. In vitro test results show that bicyclol has the effect of inhibiting the secretion of HBeAg, HBVDNA, and HBsAg in the 2.2.15 cell line of liver cancer cells transfected with human hepatitis B virus.

Ingredients

The main ingredient of this product is bicyclol.

Name Description Content CAS NO. Manufacturer
Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylateIngredients

It can reduce the increase of aminotransferase in acute liver damage in mice caused by carbon tetrachloride, D-galactosamine and paracetamol; it can reduce the increase of aminotransferase in immune hepatitis in mice; it can alleviate the pathological morphological damage of liver tissue to varying degrees; it can inhibit the secretion of HBeAg, HBVDNA and HBsAg in the 2.2.15 cell line of liver cancer cells transfected with human hepatitis B virus.

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118159-48-1 5

Appearance

This product is white tablets.

Indication

This product is suitable for the treatment of elevated aminotransferase caused by chronic hepatitis.

Usage and Dosage

Oral administration: the usual adult dose is 25 mg (1 tablet) each time, which can be increased to 50 mg (2 tablets) when necessary, 3 times a day, for at least 6 months or as directed by a doctor, and the dose should be gradually reduced.

Adverse Reactions

After taking this drug, the adverse reactions that may occur in individual patients are all mild or moderate, and generally can be relieved without stopping the drug, or by temporarily stopping the drug, or symptomatic treatment. No serious adverse reactions were found in the 1416 clinical studies. Occasionally (incidence rate 0.5%) dizziness, rash, abdominal distension, sleep disorders, abnormal hemoglobin and white blood cell counts, increased total bilirubin and transaminase, and decreased platelets were observed. In addition, very few patients (incidence rate 0.1%) experienced headaches, nausea, stomach discomfort, and transient increases in blood sugar and blood creatinine. Appropriate measures can be taken depending on the specific clinical situation.

Precautions

It is contraindicated for those who are allergic to this product or its other ingredients.

Special Population Medication

Precautions for children: The optimal dose for children under 12 years old should be prescribed by a doctor. Precautions for pregnancy and lactation: There is no research data on the use of this product in pregnant and lactating women. Like other drugs, the pros and cons should be weighed and used with caution. Precautions for the elderly: The optimal dose for patients over 70 years old has yet to be determined.

Drug Interactions

There is no research data on interactions with other drugs.

Storage

Keep sealed.

Packaging Specification

25mg

Validity Period

36 months.

Manufacturer

Beijing Xiehe Pharmaceutical Co., Ltd.

  • Founded in:

    1981-04-04
  • Address:

    Building 7, No. 37 Yongwang Road, Daxing Biomedicine Industry Base, Zhongguancun Science Park, Daxing District, Beijing
  • Tax NO.:

    91110115101618619W
  • Registered Funds:

    60 million yuan
  • Website:

  • Email:

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