Potassium chloride tablets

Potassium chloride is an electrolyte supplement. Potassium is the main cation in cells and is important for maintaining cell viability. The concentration in cells is about 150-160 mmol/L, and the concentration in extracellular fluid is lower, only 3.5-5.0 mmol/L. The body mainly relies on Na, K and ATPase on the cell membrane to maintain the difference in K and Na+ concentrations inside and outside the cell. The acid-base balance in the body affects potassium metabolism. For example, when acidosis occurs, H+ enters the cell. In order to maintain the potential difference inside and outside the cell, K+ is released outside the cell, causing Or aggravate hyperkalemia. The normal potassium ion concentration and concentration difference inside and outside the cell are closely related to certain functions of the cell. Potassium participates in the regulation of acid-base balance. The synthesis of sugar and protein and the conversion of adenosine diphosphate to triphosphate require a certain amount of potassium. Potassium participates in the excitation process between nerves and their innervated organs, between neurons, and participates in the formation of nerve terminal transmitters (acetylcholine). The potassium content in the heart can affect its activity. When potassium is low, the excitability of the heart increases. Clinically, patients with low blood potassium mainly suffer from arrhythmia. Potassium is an ion necessary to maintain normal tension of skeletal muscles. Insufficient potassium ions manifest as muscle weakness and convulsions.

The potassium chloride (KCl) content of this product should be 95.0% to 105.0% of the labeled amount

1 Treatment of hypokalemia Hypokalemia caused by various reasons, such as insufficient food intake, vomiting, severe diarrhea, the use of potassium-excreting diuretics, hypokalemic familial periodic paralysis, long-term use of glucocorticoids and supplementation of hypertonic glucose, etc. 2 Prevention of hypokalemia When patients have potassium loss, especially if hypokalemia is harmful to patients (such as patients using digitalis drugs), preventive potassium salt supplementation is required.

Oral potassium salts are used to treat mild hypokalemia or for preventive treatment. The usual dose for adults is 0.5 to 1 g (6.7 to 13.4 mmol) each time, 2 to 4 times a day, after meals, and the dose is adjusted according to the condition. The maximum daily dose for adults is 6 g (80 mmol).

1. Oral administration may cause gastrointestinal irritation symptoms such as nausea, vomiting, throat discomfort, chest pain (esophageal irritation), abdominal pain, diarrhea, and even peptic ulcer and bleeding. It is more likely to occur in patients with large fasting doses and existing gastrointestinal diseases. 2. Patients with existing renal impairment should pay attention to the occurrence of hyperkalemia.

1 Patients with hyperkalemia 2 Patients with acute renal insufficiency and chronic renal insufficiency

1. Adrenal glucocorticoids, especially those with more obvious mineralocorticoid effects, adrenal mineralocorticoids and adrenocorticotropic hormone (ACTH), can promote urinary potassium excretion, and reduce the efficacy of potassium salts when used together. 2. Anticholinergic drugs can aggravate the gastrointestinal irritation of oral potassium salts, especially potassium chloride. 3. Non-steroidal anti-inflammatory analgesics aggravate the gastrointestinal reactions of oral potassium salts. 4. When using stored blood (30mmol/L of potassium for less than 10 days of storage, 65mmol/L of potassium for more than 10 days of storage), potassium-containing drugs and potassium-sparing diuretics together, the chance of hyperkalemia increases, especially in patients with renal damage. 5. Angiotensin-converting enzyme inhibitors and cyclosporine A can inhibit aldosterone secretion and reduce urinary potassium excretion, so hyperkalemia is prone to occur when used together. 6. Heparin can inhibit the synthesis of aldosterone and reduce urinary potassium excretion, so hyperkalemia is prone to occur when used together. In addition, heparin can increase the chance of gastrointestinal bleeding. 7. Sustained-release potassium salts can inhibit the intestinal absorption of vitamin B12.

Sealed, store in a dry place.

0.25 g

Reyoung Pharmaceutical Co., Ltd.

• Founded in:

  1998-03-20

• Address:

  No. 1, Ruiyang Road, Yiyuan County, Shandong Province

• Tax NO.:

  913703001686121827

• Registered Funds:

  366.74 million yuan

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