Aripiprazole 99%
2 Inquiries
129722-12-9
Pharmaceutical Grade
99%
LIANYUNGANG
25kg/2kg Cardboard Drum
2017-01-07
Aripiprazole ,3-Methoxybenzyl chloride ,Metaldehyde ,Paraldehyde
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Product Description
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Seller Information
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Inquiry History
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DescriptionAripiprazoleChemical Name:
Aripiprazole
Molecular Formula:C23H27Cl2N3O2
Structural Formula:
CAS NO.:
129722-12-9
Quality Standard:
AppearanceOff-white or white crystalMelting Point136-142℃Heavy Metal≤ 20 ppmResidue on ignition≤0.1 %Loss on drying≤0.5 %Purity≥99% Use:25kg/cardboard with two plastic bags inner
ECHEMI Editorial ReferenceColourless Flake Crystalline SolidAripiprazole was launched for the treatment of psychoses including schizophrenia and offers a novel mechanism of action as a partial D2 receptor agonist. Aripiprazole can be synthesized in three steps beginning by the condensation of 7-hydroxy-1,2,3,4-tetrahydroquinolin-2-one with 1 ,Cdibromobutane followed by reaction with 1-(2,3-dichlorophenyl)piperazine. Aripiprazole is a significant D2 agonist/antagonist, 5-HT2 antagonis.
Solid
Aripiprazole is an N-arylpiperazine that is piperazine substituted by a 4-[(2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)oxy]butyl group at position 1 and by a 2,3-dichlorophenyl group at position 4. It is an antipsychotic drug used for the treatment of Schizophrenia, and other mood disorders. It has a role as a H1-receptor antagonist, a serotonergic agonist, a second generation antipsychotic and a drug metabolite. It is a quinolone, a N-arylpiperazine, a N-alkylpiperazine, a dichlorobenzene, an aromatic ether and a delta-lactam.|Aripiprazole is an atypical antipsychotic orally indicated for treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's. It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania. Aripiprazole exerts its effects through agonism of dopaminic and 5-HT1A receptors and antagonism of alpha adrenergic and 5-HT2A receptors. Aripiprazole was given FDA approval on November 15, 2002.|Aripiprazole is an Atypical Antipsychotic.|Aripiprazole is an atypical antipsychotic used in the treatment of schizophrenia and bipolar illness. Aripiprazole therapy has not been associated consistently with serum aminotransferase elevations and has yet to be linked to cases of clinically apparent acute liver injury.|Brexpiprazole is an atypical antipsychotic used in the treatment of schizophrenia and major depressive disorders. Brexpiprazole has been associated with a low rate of serum aminotransferase elevations during therapy, but has not been linked to instances of clinically apparent acute liver injury.|Aripiprazole is a quinoline derivate and atypical anti-psychotic agent. Aripiprazole has partial agonistic activity at dopamine D2 receptors and serotonin 5-HT1A receptors, as well as potent antagonistic activity on serotonin 5-HT2A receptors. This drug stabilizes dopamine and serotonin activity in the limbic and cortical system. Aripiprazole is used in managing symptoms of schizophrenia and of acute manic and mixed episodes associated with bipolar I disorders.|A piperazine and quinolone derivative that is used primarily as an antipsychotic agent. It is a partial agonist of SEROTONIN RECEPTOR, 5-HT1A and DOPAMINE D2 RECEPTORS, where it also functions as a post-synaptic antagonist, and an antagonist of SEROTONIN RECEPTOR, 5-HT2A. It is used for the treatment of SCHIZOPHRENIA and BIPOLAR DISORDER, and as an adjunct therapy for the treatment of depression.Basic Info-
Product Name:
Aripiprazole
Other Name:2(1H)-Quinolinone,7-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-;7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone;OPC 14597;Aripiprazole;OPC 31;7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydrocarbostyril;Abilitat;Abilify;Arpizol;Asprito;Pripiprazole;Aripiperazole;Aripirazole;Aripiprazol;Aristab;Biopiprazole;AZ 1;AZ 2;AZ 3;AZ 4;156680-99-8
CAS No.:129722-12-9
Molecular Formula:C23H27Cl2N3O2
InChIKeys:InChIKey=CEUORZQYGODEFX-UHFFFAOYSA-N
Molecular Weight:448.38500
Exact Mass:448.39
UNII:82VFR53I78
NSC Number:759266
DSSTox ID:DTXSID3046083
NCI Thesaurus Code:C47403
Color/Form:Colorless, flake crystals from ethanol
ATC Code:N05AX12|N - Nervous system
HScode:2933790090
Categories:
Characteristics-
PSA:
44.81000
XLogP3:4.6
Appearance:Solid
Density:1.263 g/cm3
Melting Point:109-111 °C @ Solvent: Methanol, Chloroform
Boiling Point:646.2ºC at 760 mmHg
Flash Point:344.6ºC
Refractive Index:1.593
Water Solubility:DMSO: soluble 5mg/mL, clear (warmed)
Storage Conditions:Store in original container in a cool dark place.
Vapor Pressure:1.38E-16mmHg at 25°C
Toxicity:TDLo ivn-dog: 0.03 mg/kg/10M TXAPA9 173,120,2001
PKA:7.6None
Henrys Law Constant:Henry's Law constant = 7.7X10-17 atm-cu m/mole at 25 °C (est)
Dissociation Constants:7.6|pKa1 = 7.46 (amide); pKa2 = 13.51 (secondary amine) (est)
Collision Cross Section:205.8 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)]|203.5 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Experimental Properties:Hydroxyl radical reaction rate constant = 3.3X10-10 cu cm/molecule-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 3, Oral
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Danger
Hazard statement(s) H301 Toxic if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Aripiprazole,3-Methoxybenzyl chloride,Metaldehyde,Paraldehyde
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Location:
Baiji, Qingshanquan, Jiawang Dist., Xuzhou, Jiangsu, China
Xuzhou Nuote Chemical Co., Ltd. (The former XU ZHOU SOLVENT FACTORY, established in 1956) is the appointed pesticide production and chemicals production company by the Ministry of P.R. China. It is patentee of the metaldehyde product.XU ZHOU SOLVENT FACTORY (Its unique legal inheritor is XU ZHOU NUO TE CHEMICAL CO., LTD) is the earliest factory to produce metaldehyde in China. It developed the metaldehyde product in 1986, and applied the patent in 1996, and was given the production technique of patent in 2000, Patent No: ZL96117046.8, International Patent Master Classification No.:007D323/00.By having ceaseless ameliorate and developed on production technique and product line in fifteen years, XU ZHOU NUO TE CHEMICAL CO.,LTD has became the major manufacturer to produce metaldehyde and molluscicide in China. It can produce 1200 tons metaldehyde per year, 3000tons 5-6% metaldehyde granule, and 50%-80%metaldehyde WP 500tons/year.By hard working, it has established integrated flow of quality control, kept jarless product quality, established professional technician team, had strong technology ability to develop new products, established finer product service, and built up good reputation. So the quantity of export is ceaselessly increasing in recent years.XU ZHOU NUO TE CHEMICAL CO., LTD expect cordially can colloquize and clasp with more customers to develop ahead together.
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Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted
Egypt
Aripiprazole
500 G Jul 10, 2025
Germany
Abilify, Humira , Nexium ,Crestor, Enbrel, Advair Diskus, Seretide, Remicade, Lantus Solostar, Neulasta
5 Jul 8, 2026 Post an enquiry for this product