5-Bromo-2'-deoxyuridine First Grade
59-14-3
Guaranteed Reagent
SHANGHAI
1kg/Papper Bag
2021-01-01
Carbohydrates,Nucleosides & Nucleotides,Ionic liquids
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Product Description
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Seller Information
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Description
5-Bromo-2′-deoxyuridine (CAS No.: 59-14-3) is supplied by Wuhu Nuowei Chemistry Technologies Co., Ltd., a Manufactory with 8 years on ECHEMI.
Key details: grade Guaranteed Reagent, packaging 1kg/Papper Bag, port SHANGHAI.
Contact the supplier on this page to request a quotation or the latest price.
ECHEMI Editorial Reference5-BrdU is a nucleoside analog that competes with thymidine for incorporation into DNA. 5-BrdU is commonly used in the detection of proliferating cells.
5-bromo-2'-deoxyuridine is a white crystalline powder. (NTP, 1992)
5-bromo-2'-deoxyuridine is a white crystalline powder. (NTP, 1992)|5-bromo-2'-deoxyuridine is a pyrimidine 2'-deoxyribonucleoside compound having 5-bromouracil as the nucleobase. It has a role as an antineoplastic agent and an antimetabolite.|Broxuridine has been used in trials studying the treatment of Leukemia, Stage I Prostate Cancer, Stage IIB Prostate Cancer, and Stage IIA Prostate Cancer.|Broxuridine is a halogenated thymidine analogue with potential antineoplastic and radiosensitizing activities. Bromodeoxyuridine competes with thymidine for incorporation into DNA, resulting in DNA mutation and the inhibition of cell proliferation. As a radiosensitizer, this agent is associated with the inhibition of repair of radiation-induced DNA double-strand breaks.|A nucleoside that substitutes for thymidine in DNA and thus acts as an antimetabolite. It causes breaks in chromosomes and has been proposed as an antiviral and antineoplastic agent. It has been given orphan drug status for use in the treatment of primary brain tumors.Basic Info-
Product Name:
5-Bromo-2′-deoxyuridine
Other Name:Uridine,5-bromo-2′-deoxy-;5-Bromo-2′-deoxyuridine;5-BDU;BDU;Bromodeoxyuridine;5-Bromodeoxyuridine;5-Bromouracil deoxyriboside;BUdR;5-Bromodesoxyuridine;Broxuridine;NSC 38297;BrdUrd;5-Bromo-2′-desoxyuridine;2′-Deoxy-5-bromouridine;BRUDR;5-Bromouracil-2-deoxyriboside;(+)-5-Bromo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione;BrdU;5-Bromouracil-2′-deoxyriboside;723-73-9;3445-26-9;1236362-78-9
CAS No.:59-14-3
Molecular Formula:C9H11BrN2O5
InChIKeys:InChIKey=WOVKYSAHUYNSMH-RRKCRQDMSA-N
Molecular Weight:307.1
Exact Mass:307.10
BRN:30395
EC Number:200-415-9
UNII:G34N38R2N1
DSSTox ID:DTXSID7033105
NCI Thesaurus Code:C318
Color/Form:Crystals from absolute ethanol
HScode:29349990
Categories:
Characteristics-
PSA:
99.1
XLogP3:-0.3
Appearance:White to yellow Crystals or Crystalline Powder
Density:1.9±0.1 g/cm3
Melting Point:192.5 °C
Refractive Index:1.652
Water Solubility:H2O: 1-5 g/100 mL at 22 ºC;NH4OH: 0.1 M at 20 °C, clear, colorless
Storage Conditions:2-8°C
Vapor Pressure:1.7X10-14 mm Hg at 25 deg C (est)
Toxicity:Oral-rat LD50: 8400 mg/kg; Oral-Mouse LD50: 9100 mg/kg
Flammability characteristics:Thermal decomposition to emit toxic nitrogen oxides and bromide fumes
Specific rotation:31 º (c=1, 0.1N NaOH)
Dissociation Constants:pKa = 7.27 (imide nitrogen) (est)
Air and Water Reactions:Water soluble.
Reactive Group:Alcohols and Polyols
Reactivity Profile:5-BROMO-2'-DEOXYURIDINE may be heat and light sensitive. (NTP, 1992).
Hazard IdentificationClassification of the substance or mixture
Germ cell mutagenicity, Category 1B
Reproductive toxicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H340 May cause genetic defects
H361 Suspected of damaging fertility or the unborn child
Precautionary statement(s) Prevention P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store solid BrdU and its solutions in dark-colored, tightly closed containers, preferably under refrigeration. Avoid exposure to light and moisture. Store working quantities of BrdU and its solutions in an explosion-safe refrigerator in the work area.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Carbohydrates,Nucleosides & Nucleotides,Ionic liquids
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Payment Terms:
TT against copy of documents
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Average lead Time:
300 days
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Total Annual Revenue:
$1 million-$2.5 million
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Total Employees:
11-50
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Year of Establishment:
2014
Wuhu Nuowei chemistry Co., Ltd. is established 2014,which is a integration of production, research and sales. The company is a high-tech pharmaceutical and biochemical enterprise. Our company follows the policy of “customer focus;service foremost; quality first;mutual benefit”.Through the well-equipped analytical instruments,the company promote high quality products to customer.
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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