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Afatinib Dimaleate cas 850140-73-7 buy - large image1
Afatinib Dimaleate cas 850140-73-7 buy - image1

Afatinib Dimaleate cas 850140-73-7

Unit Price:

$1000-1222/KG FOB

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CAS No.:

850140-73-7

Grade:

Pharmaceutical Grade

Content:

99.8%

Port:

SHANGHAI

Packaging:

0.001kg/Bottle

Price valid (until):

2029-06-06

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

prostaglandins,Polymyxin B sulfate,Clemizole hydrochloride,1,4-Diacetylbenzene,Estradiol valerate ,IMD 0354

  • Product Description

  • Seller Information

  • Description

    Afatinib dimaleate is an orally bioavailable dual receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. EGFR/HER2 tyrosine kinase inhibitor BIBW 2992 irreversibly binds to and inhibits human epidermal growth factor receptors 1 and 2 (EGFR-1; HER2), which may result in the inhibition of tumor growth and angiogenesis. EGFR/HER2 are RTKs that belong to the EGFR superfamily; both play major roles in tumor cell proliferation and tumor vascularization and are overexpressed in many cancer cell types. 


    Basic Info
    Product Name:

    Afatinib dimaleate

    Other Name:

    2-Butenamide,N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-,(2E)-,(2Z)-2-butenedioate (1:2);Afatinib dimaleate;BIBW 2992MA2;2047333-62-8

    CAS No.:

    850140-73-7

    Molecular Formula:

    C24H25ClFN5O3.2C4H4O4

    InChIKeys:

    USNRYVNRPYXCSP-JUGPPOIOSA-N

    Molecular Weight:

    718.0827232

    Exact Mass:

    717.184937

    HScode:

    29339900

    Categories:

    Other Chemical Drugs

    Characteristics
    PSA:

    238 Ų

    XLogP3:

    4.53600

    Hazard Identification

    Classification of the substance or mixture

    Not classified.

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H302 Harmful if swallowed

    H319 Causes serious eye irritation

    H361 Suspected of damaging fertility or the unborn child

    H362 May cause harm to breast-fed children

    H372 Causes damage to organs through prolonged or repeated exposure

    Precautionary statement(s)
    Prevention

    none

    Response

    none

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    prostaglandins,Polymyxin B sulfate,Clemizole hydrochloride,1,4-Diacetylbenzene,Estradiol valerate,IMD 0354

    Location:

    NO.1585 JIUYE ROAD, QINGPU DISTRICT, SHANGHAI, CHINA

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,100% TT in advance

    Average lead Time:

    7

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2011

    Certifications:

    ISO9001

    Company Profile
    Founded in 2018, Shanghai Chong Da Prostaglandin Fine Chemicals Co., Ltd. is a professional manufacturer committed to research, development and promotion of prostaglandin(PG) in both human medicine and animal health. The company also has a technical team with decades of experience in PG production.
    Chong Da now has mature technology with a complete production chain, laboratory analysis system and strict product management mode,are responsible for sales as well as experiments and development of new products .
    Our products are exported to more than 20 countries and regions, mainly in South America and Europe. The main products are: Cloprostenol Sodium, Latanoprost, Bimatoprost, Travoprost, Prostaglandin E1, E2, etc., and related derivatives, intermediates and extraction of impurities appearing in the production process.
  • Country Product Purchase Quantity Date Posted
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