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Decitabine

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CAS No.:

2353-33-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

SHANGHAI

Packaging:

10g/bag

Price valid (until):

2023-07-01

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nschem

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Chloranil,Ascomycin,Gemcitabine,Levamlodipine,Isoflurane,1-(4-Pyridyl)acetone

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Product Description
Seller Information
Inquiry History

Description

Product Detail

5-Aza-2'-deoxycytidine; Decitabine

Molecular Formula C8H12N4O4

Molecular Weight 228.20

CAS Registry Number 2353-33-5

EINECS 219-089-4

Melting point 200 ºC (dec.)

a natural 2'-deoxycytidine adenosine analogues; used for cure of MDS.

White or almost white crystalline powder, odorless,hygroscopic;

insoluble in water,slightly soluble in methanol, soluble in dimethyl sulfoxide,almost insoluble in acetoneand dichloromethane

98-102%

Basic Info

Product Name:

5-Aza-2′-deoxycytidine

Other Name:

1,3,5-Triazin-2(1H)-one,4-amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-;s-Triazin-2(1H)-one,4-amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-;4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one;5-Aza-2′-deoxycytidine;5-Azadeoxycytidine;2-Desoxy-5-azacytidine;2′-Deoxy-5-azacytidine;Decitabine;NSC 127716;DAC;Dacogen;β-Decitabine;5-Aza-2-deoxycytidine;4-Amino-1-(2-deoxy-β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one;A 2232;NSC127716;105597-46-4;123795-43-7

CAS No.:

2353-33-5

Molecular Formula:

C8H12N4O4

InChIKeys:

InChIKey=XAUDJQYHKZQPEU-KVQBGUIXSA-N

Molecular Weight:

228.21

Exact Mass:

228.21

EC Number:

219-089-4

UNII:

776B62CQ27

DSSTox ID:

DTXSID7030432

NCI Thesaurus Code:

C981

ATC Code:

L01BC08|L - Antineoplastic and immunomodulating agents

HScode:

29349990

Categories:

Antineoplastic Agents

Characteristics

PSA:

121

XLogP3:

-1.2

Appearance:

White to Off-white Powder

Density:

1.9±0.1 g/cm3

Melting Point:

198-199 °C (decomp)

Boiling Point:

485.8°C at 760 mmHg

Flash Point:

247.6±31.5 °C

Refractive Index:

1.780

Water Solubility:

acetic acid/water (1:1): 50 mg/mL

Storage Conditions:

−20°C

Vapor Pressure:

1.78E-11mmHg at 25°C

Toxicity:

Intravenous-mouse LD50: 22 mg/kg; Intraperitoneal-mouse LD50: 190 mg/kg

Flammability characteristics:

Flammable; burning produces toxic nitrogen oxide fumes

Specific rotation:

D22 +68.5° (30 min)+57.8° (6 hr) (c = 0.5 in water)

Air and Water Reactions:

Probably light and air sensitive. Water soluble. Decomposes in aqueous solution at a rate that depends on pH: at pH 7 the drug is more stable than at pH 9, but is less stable than at pH 6. At pH 7 and 99°F, approximately 7% conversion occurs in 1 hour (NTP, 1992).

Reactive Group:

Alcohols and Polyols

Reactivity Profile:

5-AZA-2'-DEOXYCYTIDINE is an organic compound with both amine and alcohol substituents. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

See More 5-Aza-2′-deoxycytidine Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Skin irritation, Category 2

Eye irritation, Category 2

Specific target organ toxicity â single exposure, Category 3

Germ cell mutagenicity, Category 2

Reproductive toxicity, Category 1B

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H302 Harmful if swallowed H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation H341 Suspected of causing genetic defects H360 May damage fertility or the unborn child
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P203 Obtain, read and follow all safety instructions before use.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P319 Get medical help if you feel unwell. P318 IF exposed or concerned, get medical advice.
Storage	P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 5-Aza-2′-deoxycytidine Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Chloranil,Ascomycin,Gemcitabine,Levamlodipine,Isoflurane,1-(4-Pyridyl)acetone

Location:
Block 4, No. 5, Torch Ave, Jiulongpo District, Chongqing,400080 China

Payment Terms:
TT against copy of documents

Average lead Time:
30

Total Annual Revenue:
$2.5 million-$5 million

Year of Establishment:
2020

nschem is a leading Manufactory supplier of Verteporfin, 2(1H)-Isoquinolinepropanoic acid, 1-[(3,4-dimethoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxy-, 2,2′-(1,5-pentanediyl) ester, ethanedioate (1:2), Milrinone based in Districts, Chongqing, China. With a commitment to quality and customer satisfaction, nschem has become a trusted name in the industry. Our product line includes a range of high-quality Verteporfin, 2(1H)-Isoquinolinepropanoic acid, 1-[(3,4-dimethoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxy-, 2,2′-(1,5-pentanediyl) ester, ethanedioate (1:2), Milrinone, which are available at competitive prices. nschem has established itself as a reliable supplier of chemical products on the echemi.com.

Inquiry History

2 Inquiries

Country	Product	Purchase Quantity	Date Posted
United Kingdom	decitabine	500 MG	May 3, 2026
United States	decitabine	1 G	Apr 27, 2026

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