Bicine, n-di (hydroxyethyl) glycine, is an amino acid derivative and one of the biological buffers. In the field of in vitro diagnosis, bicine is an important raw material for antibody detection reagents and nucleic acid detection reagents, and its appearance is white crystalline powder. Soluble in water, insoluble in acetone, DMF and other organic solvents. It is mainly used in biology and medicine. Do you know these application fields?
Bicine is often used as a buffer solution for capillary electrophoresis
Bicine is a zwitterionic buffer, which belongs to good's buffer. The pH buffer range is 7.6-9.0. Bicine is similar to glycine in molecular structure. It has a substituted amino group, a carboxyl group and two hydroxyl groups as coordination groups. Therefore, bicine has the properties of amino acid and aminoethanol at the same time. It can form metal complexes with single anion and is often used as buffer solution in capillary electrophoresis.
Bicine is an effective inhibitor for oxidative degradation of amines
According to patent cn104245089a, bicine is an effective inhibitor for the oxidative degradation of amines, which can effectively inhibit the oxidative degradation of amines or amine containing absorbents.
Application of bicine as chelating agent in soil remediation
Bicine is a kind of water-soluble amino acid analogue, which is an environmental protection material. It contains two - oh and one - COOH in the molecule. It has good chelating performance, and can chelate Cu, CD, Pb and other heavy metal ions, but can not chelate calcium and magnesium ions. Therefore, bicine is often used as a chelating agent for remediation of heavy metal contaminated soil. Bicine has good elution ability for heavy metals in neutral and acidic conditions, and can effectively remove Cu, CD and Pb ions in contaminated soil. Bicine as the active component of eluent can not only leach and repair heavy metal contaminated soil, but also avoid the loss of plant nutrients calcium and magnesium in soil, which is safe and environmentally friendly, and will not cause secondary pollution to the environment.
Bicine is also a widely used raw material for in vitro diagnostic reagents, which is suitable for Biochemistry and medicine. In the field of in vitro diagnosis, it is an important raw material for antibody detection reagent and nucleic acid detection reagent.
Hubei xindesheng Materials Co., Ltd. specializes in the production and development of biological buffer and blood collection additive, enzyme preparation, chemiluminescent reagent, luminescent substrate and other products. Desheng has been established for decades, has its own R & D team, and has researched and developed biological buffers for many years. Its products include Tris, HEPES, taps, mops, caps, bicine, EPPs, pipes and a series of biological buffers. At present, the products produced by Desheng have been sold to many countries all over the world, all of which have received high praise and re purchase, and have reached long-term cooperation with many enterprises. Interested in understanding can call consultation, Desheng welcome your call.
