(S)-3-Hydroxypyrrolidine
100243-39-8
shanghai
Huateng Pharma
upon inquiry
2022-10-10
fine chemicals,peg derivatives,pharma intermediates
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Product Description
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Seller Information
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DescriptionECHEMI Editorial Reference(S)-3-Hydroxypyrrolidine is a chiral organic compound that serves as an important building block in the synthesis of various pharmaceuticals and natural products. It is a four-membered heterocyclic amino alcohol, featuring a hydroxyl group and a stereogenic center. The 'S' prefix indicates the configuration at the stereocenter, which is crucial for its reactivity and biological activity. This compound is notable for its role as an intermediate in the synthesis of drugs, particularly those targeting the central nervous system. The enantiomeric purity of (S)-3-Hydroxypyrrolidine is often critical, as the 'R' and 'S' enantiomers can exhibit different pharmacological properties.
clear light yellow to yellow liquid after melting
The (±)-isomer is purified by repeated distillation ( b 102-104o/12mm, 108-110o/18mm), and the (±)-picrate crystallises from EtOH with m 140-141o. The R(+)-enantiomer has b 70o/0.6mm and [] D +5.6o (c 3.63, MeOH). Its hydrochloride has a negative rotation and its dimethiodide has m 230o and [] 24 -8.02o. [Suyama & Kanno Yakugaku Zasshi (J Pharm Soc Japan) 85 531 1965, Uno et al. J Heterocycl Chem 24 1025 1987, Flanagan & Joullie Heterocycles 26 2247 1987, Beilstein 21 III/IV 44.]Basic Info-
Product Name:
(S)-3-Hydroxypyrrolidine
Other Name:(S)-3-PYRROLIDINOL (S)-3-HYDROXYPYRROLIDINE;(S)-(-)-3-PYRROLIDINOL;(S)-3-PYRROLIDINOL;(S)-3-Hydroxypyrrolidine ((S)-3-Pyrrolidinol);(S)-3-HYDROXYPYROLIDINE HYDROCHLORIDE;(S)-(-)-3-Hydroxypyrrolidine, 99%, ee 99+%;(S)-3-Pyrrolidinol,99%e.e.;(S)-3-Pyrrolidinol >=97.0% (sum of enantiomers, GC)
CAS No.:100243-39-8
Molecular Formula:C4H9NO
InChIKeys:JHHZLHWJQPUNKB-BYPYZUCNSA-N
Molecular Weight:87.12
Exact Mass:87.12
BRN:4652606
EC Number:600-044-6
Color/Form:Clear light yellow to yellow
HScode:29339900
Categories:
Characteristics-
Density:
1.078 g/mL at 20 °C (lit.)
Melting Point:15°C
Boiling Point:108-110 °C (8 mmHg)
Refractive Index:n20/D1.490
Water Solubility:Fully miscible in water.
PKA:14.91±0.20(Predicted)
Critical Temperature & Pressure:2-8°C
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Seller Information
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Business Type:
Manufactory
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Main Products:
fine chemicals,peg derivatives,pharma intermediates
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Location:
Lugu Business Plaza E1,Yuelu District, Changsha City, Hunan Province
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Payment Terms:
TT against copy of documents
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Average lead Time:
30
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Total Annual Revenue:
$25 million-$50 million
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Total Employees:
301-500
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Year of Establishment:
2013
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
