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L-Cysteine | CAS 52-90-4 | amino acid fortification

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CAS No.:

52-90-4

Grade:

USP/AJI/FCC/EP grade

Content:

99%

Packaging:

25kg/Cardboard Drum

Sample Available:

Yes

Price valid (until):

2026-07-23

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PREMIUM INGREDIENT CO.,LTD

Company Type:

Manufactory

Location:

United Kingdom

Payment Terms:

TT against copy of documents,L/C

Average Lead Time:

80 days

Qualification:

Main Products:

l-lysine monohydrochloride,dl-methionine,n-acetyl-l-cysteine,l-methionine,glycine,l-cysteine hcl monohydrate

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Product Details
Seller Information
Inquiry History

Description

Basic Information

Item	Specification
Product Name	L-Cysteine
CAS No.	52-90-4
Molecular Formula	C₃H₇NO₂S
Molecular Weight	121.16
E Number	E920
Appearance	White crystalline powder
Purity	≥98.5%
Solubility	Freely soluble in water, slightly soluble in ethanol
Source Options	Glucose / Duck feathers
Implementation Standard	USP / CP / BP / EP / AJI
Certifications	ISO9001, ISO22000, HALAL, KOSHER, HACCP

Product Overview

L-Cysteine, CAS 52-90-4, is a sulfur-containing semi-essential amino acid widely supplied as high purity white crystalline powder. It serves as a key raw material for amino acid fortification, featuring strong antioxidant and reducing properties. In food processing, it works as dough conditioner and flour treatment agent to optimize baking texture and control non-enzymatic browning. For cosmetic formulations, L-Cysteine acts as an antioxidant ingredient, supporting skin barrier maintenance and anti-aging effects, and it is also applied in hair care products to adjust keratin structure. We provide food grade and pharma grade L-Cysteine that meets standard specifications, suitable for food manufacturing and cosmetic raw material formulation.

Key Characteristics

1.High-purity white crystalline powder, with excellent water solubility, easy for aqueous formulation and processing.

2.Free-base molecular structure, with higher biological activity than cysteine hydrochloride.

3.Core precursor of glutathione, with natural endogenous antioxidant and detoxification properties.

4.Dual supply sources (fermentation & animal hydrolysis) support customized requirements for different markets.

5.Stable physical and chemical properties, suitable for dry powder, capsule and tablet processing.

6.Compliant with international food additive standard E920, USP, EP, BP and AJI specifications.

Main Functions

1.Endogenous Antioxidant & Detoxification Support L-Cysteine is the key rate-limiting raw material for human glutathione synthesis. It scavenges free radicals, reduces oxidative tissue damage, and supports liver metabolic detoxification processes.

2.Keratin Synthesis Precursor It provides the sulfur required for keratin formation, improves hair cuticle repair, enhances hair toughness, and strengthens nail structure, making it a core nutrient for hair and nail health products.

3.Skin Barrier Repair & Anti-aging Promotes collagen metabolism in skin tissue, improves skin elasticity, repairs damaged skin barriers, and reduces skin oxidative aging caused by external stimulation.

4.Food Nutrition Fortification As food additive E920, it is used as amino acid fortifier in nutritional food, and acts as mild dough conditioner and browning inhibitor in baked food processing.

5.Pharmaceutical Intermediate Serves as raw material for synthesizing respiratory mucolytic agents, antioxidant preparations and amino acid infusion formulations, with high biological safety.

Main Applications

1.Dietary Supplements & Functional Food: Applied in infant formula powder, anti-aging antioxidant capsules, hair and nail health tablets, sports nutrition powder, and amino acid fortified functional food.

2.Cosmetics & Personal Care: Widely added in high-end shampoo, hair conditioner, hair repair serum, facial cleanser, moisturizing cream and other skin and hair care formulations.

3.Pharmaceutical Industry: Raw material for respiratory health preparations, mucolytic drugs, antioxidant pharmaceutical formulations, and amino acid infusion solutions.

4.Biochemical & Laboratory Use: Component of cell culture medium and microbial culture medium for biotech research and production.

Packaging and Storage

Item	Detail
Packaging	25 kg fiber drum
Storage Condition	Store in cool, dry and well-ventilated area
Handling	Keep container tightly sealed, protected from moisture and direct sunlight
Shelf Life	24 months when properly stored

ECHEMI Editorial Reference

L-Cysteine is a thiol-containing non-essential amino acid that is oxidized to form cystine.
DryPowder|Solid|White crystals; Sulferous aroma
L-cysteine is an optically active form of cysteine having L-configuration. It has a role as a flour treatment agent, a human metabolite and an EC 4.3.1.3 (histidine ammonia-lyase) inhibitor. It is a serine family amino acid, a proteinogenic amino acid, a cysteine and a L-alpha-amino acid. It is a conjugate base of a L-cysteinium. It is a conjugate acid of a L-cysteinate(1-). It is an enantiomer of a D-cysteine. It is a tautomer of a L-cysteine zwitterion.|A thiol-containing non-essential amino acid that is oxidized to form cystine.|Acetylcysteine, also known as N-acetylcysteine (NAC), is a modified amino acid that is used as an antidote for acetaminophen overdose to prevent hepatic injury. Acetylcysteine is a hepatoprotective agent and has not been linked to significant serum enzyme elevations during therapy or to instances of clinically apparent acute liver injury.|Cysteine is a non-essential sulfur-containing amino acid in humans, related to cystine, Cysteine is important for protein synthesis, detoxification, and diverse metabolic functions. Found in beta-keratin, the main protein in nails, skin, and hair, Cysteine is important in collagen production, as well as skin elasticity and texture. Also required in the manufacture of amino acid taurine, Cysteine is a component of the antioxidant glutathione, and plays a role in the metabolism of essential biochemicals such as coenzyme A, heparin, and biotin. (NCI04)|A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.

Certificates

Basic Info

Product Name:

L-(+)-Cysteine

Other Name:

L-Cysteine;Cysteine,L-;Half-cystine;β-Mercaptoalanine;Thioserine;L-(+)-Cysteine;Cysteine;Propanoic acid,2-amino-3-mercapto-,(R)-;Cystein;L-Alanine,3-mercapto-;NSC 8746;(R)-2-Amino-3-mercaptopropanoic acid;(R)-Cysteine;2-Amino-3-mercaptopropionic acid;L-Cys;E 920;(R)-2-Amino-3-mercaptopropanoic acid;(R)-2-Amino-3-sulfanylpropanoic acid;(2R)-2-Amino-3-sulfanylpropanoic acid;2-Amino-3-mercaptopropanoic acid;11: PN: WO2021055880 SEQID: 12 claimed protein;4371-52-2;154605-72-8;1404190-35-7

CAS No.:

52-90-4

Molecular Formula:

C3H7NO2S

InChIKeys:

InChIKey=XUJNEKJLAYXESH-REOHCLBHSA-N

Molecular Weight:

121.15800

Exact Mass:

121.16

EC Number:

200-158-2

UNII:

K848JZ4886

DSSTox ID:

DTXSID8022876

NCI Thesaurus Code:

C29609

Color/Form:

Colorless crystals|White crystals

HScode:

2930901000

Categories:

Amino Acids and Derivatives

Characteristics

PSA:

102.12000

XLogP3:

-2.5

Appearance:

DryPowder

Density:

1.6666 g/cm³ @ Temp: 45.00 °C

Melting Point:

240 °C (decomp)

Boiling Point:

293.9ºC at 760 mmHg

Flash Point:

131.5ºC

Refractive Index:

8.8 ° (C=8, 1mol/L HCl)

Water Solubility:

H2O: 280 g/L (25 ºC)

Storage Conditions:

Store at RT.

Vapor Pressure:

6.73X10-7 mm Hg at 25 deg C (est)

Toxicity:

LD50 orally in Rabbit: 1890 mg/kg

Specific rotation:

Specific optical rotation: +6.5 deg at 25 °C/D (5 N HCl); +13.0 deg at 25 °C/D (glacial acetic acid)

PKA:

1.71None

Henrys Law Constant:

Henry's Law constant = 5.30X10-11 atm-cu m/mol at 25 °C (est)

Dissociation Constants:

1.71|pK1 1.71 /carboxylic/; pK2 8.33 /amine/; pK3 10.78 /sulfide/

Collision Cross Section:

149.57 Å² [M+H]+ [CCS Type: DT, Method: stepped-field]|151.34 Å² [M+Na]+ [CCS Type: DT, Method: stepped-field]|144.47 Å² [M-H]- [CCS Type: DT, Method: stepped-field]|113 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine]|144 Å² [M-H]-

Experimental Properties:

Readily oxidizes to form a dimeric amino acid, cystine, in which the two cysteines are linked via a disulfide bridge, a common structural feature in proteins. Amino Acids and Proteins, D.M. Greenberg, Ed. (Charles C. Thomas, Springfield, IL, 1951) 950 pp.|In neutral or slightly alkaline aqueous solution it is oxidized to cystine by air. More stable in acidic solutions.|MP (anhydrous): 178 °C (decomposes). Specific optical rotation: +6.53 deg at 25 °C/D (calculated as cysteine) (c = 2 in 5M HCl); solubility >100 (20 °C) g/100 g H2O /L-Cysteine hydrochloride monohydrate/|Hydroxyl radical reaction rate constant = 7.96X10-11cu cm/molecule-sec at 25 °C (est)

See More L-(+)-Cysteine Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Keep container tightly closed in a dry and well-ventilated place. Store under inert gas. Air sensitive. Storage class (TRGS 510): Non Combustible Solids.

See More L-(+)-Cysteine Safety Data Sheet 

Seller Information

Business Type: Manufactory
Main Products: l-lysine monohydrochloride,dl-methionine,n-acetyl-l-cysteine,l-methionine,glycine,l-cysteine hcl monohydrate
Location: dongsheng road
Payment Terms: TT against copy of documents,L/C
Average lead Time: 80 days
Total Annual Revenue: $5 million-$10 million
Total Employees: 5-10
Year of Establishment: 2015

Premium Ingredient specializes in supplying and distributing food & feed amino acids, food additives and functional ingredients for more than a decade.

Our food additives portfolio covers phosphates, acidulants, preservatives, sweeteners, thickeners and leavening agents.

Our functional ingredients include vitamins, mineral products, botanical extracts, nutraceutical ingredients, functional fibers & bulking agents.

We serve over 100 clients across food & beverage, dietary supplement, sports nutrition, personal care, pharmaceutical and animal feed sectors, with products exported to dozens of countries worldwide. All our goods are sourced from top-tier Chinese manufacturers with proven expertise and complete management systems.

◆Amino Acids	◆ phosphates	◆ acidulants
◆ preservatives	◆ sweeteners	◆ functional fiber&bulking agent
◆ thickeners	◆ Leavening agents	◆ mineral products
◆ Botanical extracts	◆ vitamins	◆ nutritional products

Backed by over 10 years of industry experience, we provide one-stop-shop solutions combining high-grade products, prompt communication, on-time delivery and real-time market intelligence. Thanks to our long-term deep-rooted partnerships with source manufacturers, we can guarantee sufficient inventory, stable pricing and fast shipment.

Our third-party certifications include ISO9001, ISO14001, HACCP, HALAL, KOSHER, GMP, FAMI-QS and more. You can count on Premium Ingredient as your trusted global raw material supplier.

------------------------------------- Mission------------------------------------

Acting as a bridge between reliable Chinese manufacturers and global buyers, we carefully select partner factories with mature production capabilities and sound management systems. We deliver not only premium-quality raw materials, but also value-added services including market trend updates, supply chain risk alerts, product formulation consultation, consolidated sample shipment and full document support for import compliance. We timely forward overseas customers’ requirements to our partner factories to support product upgrading and achieve mutual growth.

-------------------------------------Our Quality------------------------------------

Our Quality

As a professional ingredient supplier, we do not operate manufacturing facilities. Instead, we build robust quality‑assurance workflows across our whole supply chain to safeguard consistent product performance for every shipment

Strict Supplier Due‑Diligence

Before entering any partnership, we carry out on-site factory visits and assess industry reputation, followed by multi-stage qualification reviews. We validate production qualifications, export track records, quality management systems and complete certification packages. New suppliers must pass sample evaluation, and only fully vetted top-tier factories are admitted to our approved supplier pool

Batch‑by‑batch Document Verification

For every order, we cross‑check factory‑issued test documents against agreed specifications including FCC, USP, EP, AJI, CP or your customized requirements. We will not forward documents to customers until key indicators are fully aligned with specifications. This step avoids inconsistent or mismatched documentation common in raw‑material trade.

Independent Third‑party Testing Coordination

Upon client request, we can arrange independent laboratory inspections from recognized third‑party institutions. We manage sample delivery, test protocol communication and report follow‑up to support your market compliance needs.

Quality Closure & Continuous Improvement

We keep traceable records for all delivered batches. If any quality concern arises, we act as your single point‑of‑contact to trace root causes with source factories, drive corrective actions and deliver practical resolution plans. Client feedback is systematically collected to optimize our supplier management and document‑review procedures.

We provide a comprehensive set of compliance documents to support your import and registration work. Our available documentation includes but is not limited to:

★ ISO Certification ★ Halal Certificate

★ Kosher Certificate ★ IP certificate

★ Haccp certificate ★ Allergens with Glutens

★ GRAS Statement ★ HACCP Program

★ BSE/TSE Statement ★ Certificate of Analysis

★ Country of Origin Certificate ★ Material Safety Data Sheet

★ Flow Chart (product processing) ★ Food Grade Certificate

★ Nutritional Information ★ GMO Statement

★ Specification Sheet

Inquiry History

46 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	L-cysteine	5.00 KG	Dec 2, 2025
India	L-Cysteine	100.00 KG	Jun 7, 2025
India	L-Cysteine	1.00 KG	Jul 14, 2026
India	L-Cysteine	1.00 KG	Nov 25, 2025
India	L-Cysteine	1.00 KG	May 13, 2025
India	L-Cysteine	1.00 KG	Oct 8, 2024
India	L Cyteine	25.00 KG	May 21, 2026
India	L-Cysteine	100 KG	Dec 17, 2025
India	L - CYSTINE	25.00 KG	Aug 26, 2026
India	L-Cysteine	25 KG	Aug 26, 2026
India	L-Cysteine	20.00 MT	Dec 13, 2023
India	L-Cysteine	300.00 KG	Sep 4, 2026
India	L Cysteine	25.00 KG	Jul 30, 2026
India	L-Cysteine	100 KG	Jul 29, 2026
Egypt	L-Cysteine	1.00 KG	Jul 25, 2026
India	L-Cysteine	1.00 KG	Jan 28, 2026
India	L-Cysteine	2.00 KG	Jan 27, 2026
Slovenia	L-CYSTEINE	400 KG	Jan 20, 2026
Egypt	L-Cysteine	1000 KG	Jan 19, 2026
India	L-Cysteine	1.00 KG	Sep 8, 2025

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