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Chenodeoxycholic acid 474-25-9 99% White crystalline powder

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CAS No.:

474-25-9

Content:

99%

Brand:

Packaging:

aluminium foil bag,drum

Price valid (until):

2021-06-30

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Hangzhou Go Top Peptide Biotech Co.,Ltd.

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Pharmaceutical Peptide,Cosmetic peptide,Custom peptides,API polypeptide,Amino acids and derivatives,Peptide - Teriparatide

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Product Description
Seller Information
Inquiry History

Description

Hangzhou Go Top Peptide Biotech is a technology-based and ISO9001-CERTIFIED peptide company and National High-tech Enterprise located in Hangzhou, China. Main service include Custom peptide synthesis, Peptide CRO/CDMO,Non-GMP and GMP peptide, Cosmetic peptide.

Pharmaceutical Peptide:

Semaglutide,Liraglutide,Dulaglutide,Thymalfasin,Eptifibatide,Leuprolide Acetate, Etelcalcetide,Teduglutide,Abaloparatide,Terlipressin,Aviptadil,Icatibant,Bremelanotide

Cosmetic Peptide:

Conotoxin / Conopeptide, Copper peptide / GHK-Cu,Acetyl hexapeptide-8/ Argireline, Nonapeptide-1, Glutathione,Palmitoyl Pentapeptide-4 and more.

Custom Peptide and CDMO

We provide Custom Peptide Synthesis with modifications from lab scale to pilot scale and Commercialization. Production capacity is from milligram to multi-kilograms.

The company web site: https://www.gtpeptide.com

ECHEMI Editorial Reference

Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.
Solid
Chenodeoxycholic acid is a dihydroxy-5beta-cholanic acid that is (5beta)-cholan-24-oic acid substituted by hydroxy groups at positions 3 and 7 respectively. It has a role as a human metabolite and a mouse metabolite. It is a bile acid, a dihydroxy-5beta-cholanic acid and a C24-steroid. It is a conjugate acid of a chenodeoxycholate.|Chenodeoxycholic acid (or Chenodiol) is an epimer of ursodeoxycholic acid (DB01586). Chenodeoxycholic acid is a bile acid naturally found in the body. It works by dissolving the cholesterol that makes gallstones and inhibiting production of cholesterol in the liver and absorption in the intestines, which helps to decrease the formation of gallstones. It can also reduce the amount of other bile acids that can be harmful to liver cells when levels are elevated.|Chenodeoxycholic acid (chenodiol) is a primary bile acid, synthesized in the liver and present in high concentrations in bile that is used therapeutically to dissolve cholesterol gallstones. Chronic therapy is associated with transient elevations in serum aminotransferase levels in up to 30% of patients, but chenodiol has been linked to only rare instances of clinically apparent liver injury with jaundice.|A bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorbed by the small intestine. It is used as cholagogue, a choleretic laxative, and to prevent or dissolve gallstones.

Basic Info

Product Name:

Chenodeoxycholic acid

Other Name:

Cholan-24-oic acid,3,7-dihydroxy-,(3α,5β,7α)-;5β-Cholan-24-oic acid,3α,7α-dihydroxy-;5β-Cholanic acid,3α,7α-dihydroxy-;(3α,5β,7α)-3,7-Dihydroxycholan-24-oic acid;Anthropodeoxycholic acid;Anthropodesoxycholic acid;Chenodeoxycholic acid;Chenodesoxycholic acid;3α,7α-Dihydroxycholanic acid;Gallodesoxycholic acid;17β-(1-Methyl-3-carboxypropyl)etiocholane-3α,7α-diol;3α,7α-Dihydroxy-5β-cholanic acid;3α,7α-Dihydroxy-5β-cholanoic acid;Anthropododesoxycholic acid;CDC;3α,7α-Dihydroxy-5β-cholan-24-oic acid;Chenic acid;Chendol;Chenodiol;7α-Hydroxylithocholic acid;Chenofalk;Chenix;Chenocol;Chenodex;Hekbilin;Ulmenide;Cholanorm;Fluibil;Chenocedon;Kebilis;Chenossil;(+)-Chenodeoxycholic acid

CAS No.:

474-25-9

Molecular Formula:

C24H40O4

InChIKeys:

InChIKey=RUDATBOHQWOJDD-BSWAIDMHSA-N

Molecular Weight:

392.57200

Exact Mass:

392.57

EC Number:

207-481-8

UNII:

0GEI24LG0J

DSSTox ID:

DTXSID2020260

ATC Code:

A05AA01|A - Alimentary tract and metabolism

HScode:

2918990090

Categories:

Drugs Influencing Immune Function

Characteristics

PSA:

77.76000

XLogP3:

4.47790

Appearance:

white to off-white crystalline powder

Density:

1.128g/cm3

Melting Point:

119 °C

Boiling Point:

547.1ºC at 760 mmHg

Flash Point:

298.8ºC

Refractive Index:

1.558

Water Solubility:

Practically insoluble in water

Storage Conditions:

Store in a cool, dry place. Store in a tightly closed container.

Collision Cross Section:

201.51 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|206.57 Å² [M-H]- [CCS Type: DT, Method: stepped-field]|202.3 Å² [M-H]- [CCS Type: DT, Method: single field calibrated]|186.9 Å² [M+H-2H2O]+ [CCS Type: DT, Method: single field calibrated]|202.8 Å² [M+H-H2O]+ [CCS Type: DT, Method: single field calibrated]|201.9 Å² [M+HCOO]- [CCS Type: DT, Method: single field calibrated]|208.5 Å² [M+K-H+HCOO]- [CCS Type: DT, Method: single field calibrated]|224.5 Å² [M+K-H+HCOO]- [CCS Type: DT, Method: single field calibrated]|199.2 Å² [M+Na-H+Cl]- [CCS Type: DT, Method: single field calibrated]|205.8 Å² [M+Na-H+HCOO]- [CCS Type: DT, Method: single field calibrated]|205.9 Å² [M-H]-

See More Chenodeoxycholic acid Properties 

Hazard Identification

Classification of the substance or mixture

Skin irritation, Category 2

Eye irritation, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H315 Causes skin irritation H319 Causes serious eye irritation
Prevention	P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Chenodeoxycholic acid Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Pharmaceutical Peptide,Cosmetic peptide,Custom peptides,API polypeptide,Amino acids and derivatives,Peptide - Teriparatide

Location:
5th Floor, Building 1, No. 600 Yinhai Street, Xiasha Street

Payment Terms:
TT against copy of documents

Average lead Time:
7

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2014

Hangzhou Go Top Peptide Biotech , established in 2014, is a technology-based peptide company and a National High-tech Enterprise located in Hangzhou of China. It is also the governing unit of Peptide Branch of China Biochemical Pharmaceutical Industry Association.
The company currently has a peptide research center in Hangzhou, covering an area of 2,000m2 . There are two cooperation plants for peptide commercialization located in Shangyu and Anji of Zhejiang province. The peptide center has equipped with several complete peptide productions lines, including several large-scale peptide synthesizers and advanced imported HPLC systems with different sizes. We also have GMP standard clean laboratories to meet client’s special needs. The company has passed ISO9001:2015 certification.
At present, the company has developed more than 40 mature pharmaceutical peptides, with the annual production capacity up to 100 kilograms. With a total of 20,000 custom peptides so far, we can provide the one-stop peptide services from research scale (mg) - pilot scale - commercial production(KGs).

English web site https://www.gtpeptide.com
Products and Services
1.Custom peptide synthesis, such as Research peptide, Neoantigen peptide, Clinical peptide.
2.Pharmaceutical peptide development and production.
3.Peptide CRO and CDMO.
4. Cosmetic peptide and formulation development.
5. Special protected amino acids and small molecules.
6. Commercialized peptide library.
7. Technical support of new drug development.

SHELLY HU Director of sales 13735575465 sales1@gotopbio.com
Cindy Mei The sales manager 13588827304 sales3@gotopbio.com

Inquiry History

2 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	Pharmaceutical Chenodeoxycholic Acid CAS 474-25-9 Purity 99% with USP Standard	1000 KG	Aug 30, 2023
India	Chenodeoxycholic Acid	5 KG	Mar 18, 2026

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SHELLY HU	Director of sales	13735575465	sales1@gotopbio.com
Cindy Mei	The sales manager	13588827304	sales3@gotopbio.com

Chenodeoxycholic acid 474-25-9 99% White crystalline powder

Product Description

Seller Information