Product
Supplier
Encyclopedia
Inquiry
Elagolix buy - large image1
Elagolix buy - image1

Elagolix

1 Inquiries

Unit Price: Get Latest Price
CAS No.:

834153-87-6

Packaging:

1g/bag

Price valid (until):

2024-12-08

Company Type:
Distributor
Location:
China
Qualification:
Main Products:

API,Intermediate

  • Product Description

  • Seller Information

  • Inquiry History

  • Description
    ItemsSpecifications
    Product nameElagolix
    CAS number834153-87-6
    AppearanceWhite powder
    SolubilityFreely soluble in water, Acetonitrile or methanol
    Total impuritiesNot more than 1.0%
    ContentNot less than 99.0%


      Product Detail  


    Elagolix is a gonadotropin-releasing hormone antagonist (GnRH antagonist) medication which is used in the treatment of pain associated with endometriosis in women.It is also under development for the treatment of uterine fibroids and heavy menstrual bleeding in women.The medication was under investigation for the treatment of prostate cancer and enlarged prostate in men as well, but development for these conditions was discontinued. Elagolix is taken by mouth once or twice per day. It can be taken for up to 6 to 24 months, depending on the dosage.

    Elagolix was first described in 2008 and was approved for medical use in July 2018. It has been described as a "second-generation" GnRH modulator due to its non-peptide and small-molecule nature and its oral activity. Unlike GnRH agonists and older GnRH antagonists, which are peptides and first-generation GnRH modulators, elagolix is not a GnRH analogue as it is not structurally related to GnRH. Elagolix was the first second-generation and orally active GnRH modulator to be introduced for medical use. The introduction of elagolix in the United States and Canada was followed by that of relugolix (brand name Relumina), the next second-generation GnRH antagonist, in Japan in January 2019. The U.S. Food and Drug Administration (FDA) considers it to be a first-in-class medication.

    img

    This product is for R&D use only.

    Basic Info
    Product Name:

    Elagolix

    Other Name:

    Butanoic acid,4-[[(1R)-2-[5-(2-fluoro-3-methoxyphenyl)-3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-3,6-dihydro-4-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-1-phenylethyl]amino]-;4-[[(1R)-2-[5-(2-Fluoro-3-methoxyphenyl)-3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-3,6-dihydro-4-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-1-phenylethyl]amino]butanoic acid;NBI 56418;Elagolix;(R)-4-((2-(5-(2-Fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)amino)butanoic acid

    CAS No.:

    834153-87-6

    Molecular Formula:

    C32H30F5N3O5

    InChIKeys:

    InChIKey=HEAUOKZIVMZVQL-VWLOTQADSA-N

    Molecular Weight:

    631.595

    Exact Mass:

    631.59

    UNII:

    5B2546MB5Z

    DSSTox ID:

    DTXSID40232348

    NCI Thesaurus Code:

    C153373

    ATC Code:

    H - Systemic hormonal preparations, excl. sex hormones and insulins

    Categories:

    Antineoplastic Agents

    Characteristics
    PSA:

    99.2

    XLogP3:

    7.20

    Density:

    1.4±0.1 g/cm3

    Boiling Point:

    728.6±70.0 °C at 760 mmHg

    Flash Point:

    394.5±35.7 °C

    Refractive Index:

    1.567

    Water Solubility:

    <1 mg/mL

    Hazard Identification

    Classification of the substance or mixture

    Reproductive toxicity, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H361 Suspected of damaging fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Distributor

    Main Products:

    API,Intermediate

    Payment Terms:

    TT against copy of documents,L/C

    Average lead Time:

    30

    Total Annual Revenue:

    Above $100 million

    Total Employees:

    201-300

    About Echemi Pharmaceutical 

    Echemi’s philosophy is to seek for higher quality, to explore frontier area. The progress of human society, the extension of life expectancy, and the conquest of disease are all derived from the numerous businesses and individuals who have quietly dedicated themselves in the pharmaceutical industry. It’s the controlling of supply chain quality that ensures the efficacy. It’s the continuous exploration that promotes the development of the pharmaceutical industry and benefits more future generations. The pursuit of high quality requires all partners of Echemi Pharmaceutical to be screened, whether its certificate, qualification or scale. In the field of renewal, we will embrace all new changes and make more contributions to the development of pharmaceutical industry.

    5c54b7e7a92e19d38f90f7daf858e202.png

    Advantage for Pharmaceutical 

    • Having been working in pharmaceutical field for more then 15 years, we have experienced regulatory team, quality control team, sourcing team, technical support team, and logistics team. And we are familiar with the regulatory requirements from different areas, can offer tailored service for our customers.

    • We have hundreds of strategic partners for APIs, intermediates, and custom synthesis. All of our partners are ready to support our customers with documents, and be audited.

    • We can offer custom synthesis for some new chemical structures and some materials which there are no reliable suppliers.

    2c0ca90da4086f3a1b7df867d79e8bba.png

    Product Category 

    We care for human and animal health and we are committed to creating a better social environment.

    •  Human API

    • Intermediate

    • Veterinary API

    • Agrochemical

    • Fine Chemical

    • Custom Synthesis



  • Inquiry History
    1 Inquiries
    Country Product Purchase Quantity Date Posted
    Pakistan

    ELAGOLIX

    50 KG Mar 17, 2025
    Post an enquiry for this product
pic ×

Scan the QR Code to Share

All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.

According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.

The information shown above is provided by the enterprise itself, and the authenticity, accuracy and legitimacy of the content are the responsibility of the publishing company. ECHEMI does not bear any guarantee responsibility for this. Please be aware that risks in internet transactions objectively exist.

Feedback & Suggestions
Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.