Vonoprazan( Cas No.:881681-00-1)
6 Inquiries
881681-00-1
Pharmaceutical Grade
99%
Guangzhou
HRD
25kg/drum
2021-10-29
Fimasartan and intermediates,Ticagrelor and intermediates,Oseltamivir Phosphate and intermediates,Edoxaban (tosylate),Fluvoxamine maleate and intermediates,Orlistat and Intermediates
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceTAK-438 (free base) is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+ ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretion.IC50 value: 19 nM [1]Target: H+/K+ ATPasein vitro: TAK-438 is a pyrrole derivative with a chemical structure that is completely different from the P-CABs developed to date. TAK-438 inhibits gastric H+/K+ ATPase activity in a concentration-dependent manner. Under neutral conditions (pH 7.5), the inhibitory activity of
Vonoprazan is a member of pyrroles.|Vonoprazan has been used in trials studying the treatment of Erosive Esophagitis.Basic Info-
Product Name:
Vonoprazan
Other Name:1H-Pyrrole-3-methanamine,5-(2-fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-;5-(2-Fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-methanamine;1-[5-(2-Fluorophenyl)-1-[(pyridin-3-yl)sulfonyl]-1H-pyrrol-3-yl]-N-methylmethanamine;Vonoprazan;TAK 438 free form
CAS No.:881681-00-1
Molecular Formula:C17H16FN3O2S
InChIKeys:InChIKey=BFDBKMOZYNOTPK-UHFFFAOYSA-N
Molecular Weight:345.3912432
Exact Mass:345.39
EC Number:0
UNII:1R5L3J156G
DSSTox ID:DTXSID20236869
ATC Code:A - Alimentary tract and metabolism
Categories:
Characteristics-
PSA:
72.4
XLogP3:2
Density:1.3±0.1 g/cm3
Boiling Point:530.3±60.0°C at 760 mmHg
Flash Point:274.5±32.9 °C
Refractive Index:1.622
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Seller Information
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Business Type:
Manufactory
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Main Products:
Fimasartan and intermediates,Ticagrelor and intermediates,Oseltamivir Phosphate and intermediates,Edoxaban (tosylate),Fluvoxamine maleate and intermediates,Orlistat and Intermediates
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Location:
No.2 Workshop, NO.10 Yonghui Road, Sanzao Town, Jinwan District, Zhuhai City, Guangdong Province, China
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A
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Average lead Time:
7 days
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Total Annual Revenue:
$10 million-$25 million
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Total Employees:
51-100
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Year of Establishment:
2009
Company Certificates-
Business Lincense
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High-tech Enterprise
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IP
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ISO
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Inquiry History6 Inquiries
Country Product Purchase Quantity Date Posted
South Korea
Vonoprazan
1 KG Jun 4, 2026
Jordan
Vonoprazan
1 KG Apr 15, 2025
India
Vonoprazan
50 MG Aug 13, 2024
India
Venlafaxine Hcl
400 KG Apr 14, 2025
United States
Vonoprazan
500 G Dec 31, 2024
Egypt
Vonoprazon
100 G Nov 1, 2023 Post an enquiry for this product
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