Product
Supplier
Encyclopedia
Inquiry

EN

Home > Encyclopedia > Vonoprazan

Vonoprazan

Vonoprazan structure
  • CAS No:

    881681-00-1

  • Formula:

    C17H16FN3O2S

  • Synonyms:

    Vonoprazan;1-[5-(2-Fluorophenyl)-1-[(pyridin-3-yl)sulfonyl]-1H-pyrrol-3-yl]-N-methylmethanamine;1H-Pyrrole-3-methanamine,5-(2-fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl);TAK-438 (free base)

  • Categories:

    API  >  Digestive System Drugs

Request for Quotation

Description

TAK-438 (free base) is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+ ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretion.IC50 value: 19 nM [1]Target: H+/K+ ATPasein vitro: TAK-438 is a pyrrole derivative with a chemical structure that is completely different from the P-CABs developed to date. TAK-438 inhibits gastric H+/K+ ATPase activity in a concentration-dependent manner. Under neutral conditions (pH 7.5), the inhibitory activity of

View AllView Less

Basic Attributes

  • 881681-00-1

  • C17H16FN3O2S

  • 345.3912432

  • 345.094727

  • 72.4

  • 2

  • 0

  • BFDBKMOZYNOTPK-UHFFFAOYSA-N

  • 5

  • 1

  • 0.12

  • 5

Characteristics

  • 1.3±0.1 g/cm3

  • 530.3±60.0°C at 760 mmHg

  • 274.5±32.9 °C

  • 1.622

Safety Information

Price Analysis

  • 2022-03-18

    USD offers of Vonoprazan is 2626.8USD/KG FCA Shanghai.

Learn More Other Chemicals

Scan the QR Code to Share

Suggestions
Email:
Message:
Send Message