High Purity Thymosin β4 (1-4) CAS: 127103-11-1 for Lab Use
127103-11-1
Pharmaceutical Grade
98%
chengdu
Youngshe
1g/bottle ,5g/bottle, 10g/bottle or customization
2030-12-30
Cosmetic peptides,beauty raw materials,custom peptides,pharmaceutical intermediates
-
Product Description
-
Seller Information
-
DescriptionECHEMI Editorial ReferenceN-Acetyl-Ser-Asp-Lys-Pro is a natural and specific substrate for the N-terminal site of ACE.Basic Info
-
Product Name:
AC-SER-ASP-LYS-PRO-OH
Other Name:SERASPENIDE;ACETYL-SER-ASP-LYS-PRO;AC-SDKP;AC-SDKP-DELTA;AC-SER-ASP-LYS-PRO;AC-SER-ASP-LYS-PRO-OH;GORALATIDE;Ac-L-Ser-L-Asp-L-Lys-L-Pro-OH
CAS No.:127103-11-1
Molecular Formula:C20H33N5O9
Molecular Weight:487.5
Exact Mass:487.227814
Categories:
Characteristics-
PSA:
238.93000
XLogP3:-1.91
Appearance:White to off-white Solid
Density:1.4±0.1 g/cm3
Boiling Point:992.0±65.0 °C at 760 mmHg
Flash Point:553.7±34.3 °C
Refractive Index:1.565
Water Solubility:Soluble in water at 2mg/ml
Storage Conditions:−20°C
Research-
Class:
Actin-sequestering protein / 43-amino-acid peptide
Status:Research compound — Not FDA approved (investigational: RGN-259 for dry eye / neurotrophic keratitis)
Mechanism:A naturally occurring 43-amino-acid peptide (Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH) that binds G-actin (sequesters monomeric actin), preventing F-actin polymerization. Promotes cell migration, angiogenesis, wound healing, and anti-inflammatory responses via integrin-linked kinase (ILK) and HIF-1α/VEGF pathways. TB-500 is the synthetic fragment Ac-LKKTETQ (MW ~895) often sold under this CAS.
Activity note:Thymosin Beta-4 is an actin-binding protein, not a receptor agonist. Functional activity is measured by actin sequestration (Kd ~0.7–1 μM) and cell migration assays, not EC₅₀.
Source:Goldstein AL, et al. Vitam Horm. 2003;66:257–296. RegeneRx RGN-259 clinical program.DOI
Clinical Development:
References-
DrugBank:PubChem:UNII:Disclaimer:
Thymosin Beta-4 (TB-500) is NOT FDA-approved for human therapeutic use. RGN-259 (Tβ4 ophthalmic solution) is an investigational drug not yet approved. TB-500 sold on research-chemical marketplaces is a synthetic fragment and is not an approved medicine. This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
-
-
Seller Information
-
Business Type:
Manufactory
-
Main Products:
Cosmetic peptides,beauty raw materials,custom peptides,pharmaceutical intermediates
-
Location:
Unit 12, Building 10, No.77, Tianmu Road, Gaoxin West District, Yi County, Chengdu City, Sichuan Province
-
Payment Terms:
TT against copy of documents
-
Average lead Time:
7
-
Total Annual Revenue:
$1 million-$2.5 million
-
Total Employees:
11-50
-
Year of Establishment:
2015
-
Certifications:
ISO9001
Chengdu YoungShe Chemical Co., Ltd is a new and dynamic high-tech enterprise that is constantly innovating and specializing in the development of beauty peptides. The company is headquartered in Chengdu Hi-tech Development Zone. Since its establishment in early 2015, the company has launched hundreds of beauty peptide products with different functions, which are widely sold at home and abroad.
Chengdu Youngshe Chemical Co., Ltd.'s main cosmetic peptide products are dipeptide, tripeptide, tetrapeptide, pentapeptide, hexapeptide, and seven peptides ( heptapeptide, octapptide, nonapeptide, decapeptide, and oligopeptide.
-
-
Country Product Purchase Quantity Date Posted Post an enquiry for this product
