Alpha-Pinene Haihang Alpha-Pinene CAS 1686-14-2
2437-95-8
Shanghai, China
25kg/Drum
2022-12-31
Dichloromethane,Linocaine hydrochloride
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Product Description
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Seller Information
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Description
Effect :Melting point -55 °C Boiling point 155-156 °C(lit.) density 0.858 g/mL at 25 °C(lit.) refractive index n20/D 1.465(lit.) Fp 90 °F CAS DataBase Reference 2437-95-8(CAS DataBase Reference)
1. Anti-tumor effect ZhangZ et al., in the study of the effect of α-pinene on non-small cell lung cancer, treated α-pinene with paclitaxel to treat A549 cells, and the combined drug method can increase the effect of paclitaxel in inhibiting tumors. The results show that α-pinene can significantly promote tumor cell apoptosis. This is mainly due to the synergistic effect produced when combined with paclitaxel. Further research mechanisms have shown that when α-pinene and paclitaxel are used in combination, the ratio of cells in G0/G1 phase can be significantly increased, and there are changes in cell morphological characteristics, such as chromatin pyknosis, nuclear fragmentation, etc., to cause The production of tumor cell apoptosis.
2. Antifungal effect: The main components of the cell wall of Candida albicans are chitin, glucose and mannan, the chemical composition of the cell membrane is mainly ergosterol, the nucleic acid is mainly DNA, and a small amount of RNA. The synthesis of these components can lead to the death of bacterial cells. Xia Zhongdi and others found that α-pinene can significantly inhibit the synthesis of chitin and polysaccharides in the cell wall of Candida albicans, the synthesis of ergosterol in the cell membrane, and the synthesis of nucleic acid DNA and ChemicalbookRNA. Among them, the inhibition of the synthesis of ergosterol is more obvious. PichetteA and other studies also found that α-pinene has anti-inflammatory, antibacterial and anti-oxidant effects.
3. Anti-allergic and improving ulcer effects. In the research on the inhibitory effect of α-pinene on allergic rhinitis in mice by NamSY et al., it was found that the expression of IL-4 in spleen lymphocytes decreased, and the IgE, α-TNF, ICAM in the nasal mucosa -1 and macrophage inflammatory protein-2 decreased. The increased eosinophils and mast cells in mice were also significantly reduced after α-pinene treatment. In addition, in the study of the effect of α-pinene on the human mast cell line HMC-1, α-pinene can inhibit the phosphorylated RIP2, IKK-β, NF-κB and caspase-1 activities after sensitization. Therefore, α-pinene is considered an anti-allergic agent. In the study of improving ulcers, the α-pinene extracted from the oil of PinheiroMdeA et al. treated mice with gastric ulcers, and it was found that α-pinene has significant anti-ulcer activity.
Basic Info-
Product Name:
ALPHA-PINENE
Other Name:DL-A-PINENE;CYCLIC DEXADIENE;FEMA 2902;BICYCLO [3.1.1] HEPT-2-ENE, 2,6,6-TRIMETHYL;4,7,7-trimethylbicyclo[3.1.1]hept-3-ene;beta-PINENE, 90% +;DL-α-Pinene;Bicyclo[3.1.1]hept-2-ene,2
CAS No.:2437-95-8
Molecular Formula:C10H16
InChIKeys:GRWFGVWFFZKLTI-JQEWEITDNA-N
Molecular Weight:136.23
Exact Mass:136.23
EC Number:219-445-9
HScode:29021910
Categories:
Characteristics-
PSA:
0
XLogP3:4.83
Appearance:Liquid
Density:0.858 g/mL at 25 °C(lit.)
Melting Point:-55 °C
Boiling Point:155-156 °C(lit.)
Flash Point:90 °F
Refractive Index:n20/D1.465(lit.)
Water Solubility:In water, 2.49 mg/L at 25 deg C
Storage Conditions:Keep container closed. Keep away from heat, sparks, and open flame.
Vapor Pressure:4.75 mm Hg at 25 deg C
Vapor Density:4.7 (Air = 1)
Hazard IdentificationClassification of the substance or mixture
Skin irritation, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H315 Causes skin irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Keep container closed. Keep away from heat, sparks, and open flame.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Dichloromethane,Linocaine hydrochloride
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Location:
BUILDING 1,HISENSE INTELLIGENCE VALLEY,NO.2116,OF PHOEIX ROAD, HIGH-TECH ZONE ,JINAN CITY ,SHANDONG PROVINCE,CHINA
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Payment Terms:
D/P,L/C,D/A
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Average lead Time:
15
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Total Annual Revenue:
$10 million-$25 million
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Total Employees:
11-50
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Year of Establishment:
2016
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
