Zafirlukast >=98.0% Pharmaceutical API made in china
107753-78-6
2026-09-29
D-Biotin,Tobramycin base,L(-)-Carnitine base,Polymyxin B sulfate USP,Kanamycin sulfate monohydrate,Finasteride 99% USP
-
Product Description
-
Seller Information
-
DescriptionHangzhou Dawn Ray Pharmaceutical Co.,Ltd, with approximately 67657 visits to its shop, is a reputable Manufactory that has been providing Zafirlukast >=98.0% Pharmaceutical API made in china products for 5 years on ECHEMI.ECHEMI Editorial ReferenceZafirlukast is a potent orally active leukotriene D4 (LTD4) receptor antagonist.
Solid
Zafirlukast is a member of indoles, a carbamate ester and a N-sulfonylcarboxamide. It has a role as an anti-asthmatic agent and a leukotriene antagonist.|Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. It is available as a tablet and is usually dosed twice daily. Another leukotriene receptor antagonist is montelukast (Singulair), which is usually taken just once daily. Zafirlukast blocks the action of the cysteinyl leukotrienes on the CysLT1 receptors, thus reducing constriction of the airways, build-up of mucus in the lungs and inflammation of the breathing passages.|Zafirlukast is a Leukotriene Receptor Antagonist. The mechanism of action of zafirlukast is as a Leukotriene Receptor Antagonist, and Cytochrome P450 2C9 Inhibitor.|Zafirlukast is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma. Zafirlukast has been linked to rare, but occasionally severe cases of acute liver injury.|Zafirlukast is a tolyl compound and leukotriene receptor antagonist (LTRA), with anti-asthmatic and potential capsular contracture-preventing activities. Upon administration, zafirlukast selectively and competitively binds to and blocks the cysteinyl leukotriene 1 receptor (CYSLTR1), thereby preventing the potent pro-inflammatory mediators leukotriene C4, D4 and E4 from binding. This prevents leukotriene-mediated actions, including enhanced migration of eosinophils and neutrophils, increased adhesion of leukocytes, increased monocyte and neutrophil aggregation, increased airway edema, inflammation, capillary permeability and bronchoconstriction. In addition, zafirlukast may decrease collagen deposition, fibrosis, and capsular thickness after implantation, thereby preventing scar tissue.Basic Info-
Product Name:
Zafirlukast
Other Name:Carbamic acid,N-[3-[[2-methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-1H-indol-5-yl]-,cyclopentyl ester;Carbamic acid,[3-[[2-methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-1H-indol-5-yl]-,cyclopentyl ester;ICI 204219;Cyclopentyl 3-[2-methoxy-4-[(o-tolylsulfonyl)carbamoyl]benzyl]-1-methylindole-5-carbamate;Zafirlukast;Accolate;Vanticon;S 1633;[3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-benzyl]-1-methyl-1H-indol-5-yl]-carbamic acid cyclopentyl ester
CAS No.:107753-78-6
Molecular Formula:C31H33N3O6S
InChIKeys:InChIKey=YEEZWCHGZNKEEK-UHFFFAOYSA-N
Molecular Weight:575.68
Exact Mass:575.68
UNII:XZ629S5L50
DSSTox ID:DTXSID5023746
NCI Thesaurus Code:C47785
ATC Code:R - Respiratory system
Categories:
Characteristics-
PSA:
131.09000
XLogP3:6.15
Appearance:Solid
Density:1.3±0.1 g/cm3
Melting Point:138-140 °C
Refractive Index:1.641
Water Solubility:DMSO: ≥28mg/mL
Storage Conditions:Refrigerator
Hazard IdentificationClassification of the substance or mixture
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 4
GHS label elements, including precautionary statements
Pictogram(s) No symbol. Signal word No signal word
Hazard statement(s) H413 May cause long lasting harmful effects to aquatic life
Precautionary statement(s) Prevention P273 Avoid release to the environment.
Response none
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
-
-
Seller Information
-
Business Type:
Manufactory
-
Main Products:
D-Biotin,Tobramycin base,L(-)-Carnitine base,Polymyxin B sulfate USP,Kanamycin sulfate monohydrate,Finasteride 99% USP
-
Location:
1613 Guangyin Building,No.42 E.Fengqi Road,Hangzhou,310012 China.
-
Payment Terms:
TT against copy of documents,L/C
-
Average lead Time:
7
-
Total Annual Revenue:
$25 million-$50 million
-
Total Employees:
11-50
-
Year of Establishment:
2011
-
-
Country Product Purchase Quantity Date Posted Post an enquiry for this product
