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4-Amino-3-chlorophenol

1 Inquiries

Unit Price: Get Latest Price
CAS No.:

17609-80-2

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Beijing/Shanghai/Jinan/Qingdao/other importment

Brand:

Boyuan

Packaging:

25kg Carboard Crub

Price valid (until):

2023-12-31

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Terbinafine hydrochloride,Carboplatin,Pramipexole dihydrochloride Monohydrate,Cisatracurium Besylate,Rivaroxaban,Lenvatinib

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    4-Amino-3-Chlorophenol acts as a synthetic reagent for the preparation of Benzothiazole-based ureas as potential ABAD/17β-HSD10 modulators for Alzheimer''s disease treatment.

    Melting point  159-160℃
    Boiling point  287.3±25.0 °C(Predicted)
    density  1.406±0.06 g/cm3(Predicted)
    RTECS  SJ5710000
    storage temp.  2-8°C(protect from light)
    solubility  DMSO (Slightly), Methanol (Slightly)
    pka 9.26±0.18(Predicted)
    form  Crystalline Powder
    color  White
    Stability: Hygroscopic
    CAS DataBase Reference 17609-80-2(CAS DataBase Reference)

    Introduction

    4-Amino-3-chlorophenol is an important pharmaceutical chemical intermediate, widely used in the design and synthesis of anti-tumour, cardiovascular disease, neurological disease, etc. It is an important intermediate in the preparation of the novel tyrosine kinase inhibitors Tivozanib and Lenvatinib.


    Uses

    4-Amino-3-chlorophenol belongs to phenolic derivatives and can be used as an intermediate of Lenvatinib(Lovatinib).

    Basic Info
    Product Name:

    4-Amino-3-chlorophenol

    Other Name:

    Phenol,4-amino-3-chloro-;4-Amino-3-chlorophenol;1-Hydroxy-4-amino-3-chlorobenzene;3-Chloro-4-aminophenol;3-Chloro-p-aminophenol;2-Chloro-4-hydroxyaniline

    CAS No.:

    17609-80-2

    Molecular Formula:

    C6H6ClNO

    InChIKeys:

    InChIKey=PNLPXABQLXSICH-UHFFFAOYSA-N

    Molecular Weight:

    143.57

    Exact Mass:

    143.57

    EC Number:

    241-583-3

    DSSTox ID:

    DTXSID30170083

    HScode:

    2922299090

    Categories:

    Antineoplastics

    Characteristics
    PSA:

    46.2

    XLogP3:

    1.9

    Appearance:

    White Crystalline Powder

    Density:

    1.406±0.06 g/cm3(Predicted)

    Melting Point:

    159.5 °C

    Boiling Point:

    287.3±25.0 °C(Predicted)

    Flash Point:

    127.6±23.2 °C

    Refractive Index:

    1.651

    Vapor Pressure:

    0.00074mmHg at 25°C

    Hazard Identification

    Classification of the substance or mixture

    Skin irritation, Category 2

    Acute toxicity - Category 4, Inhalation

    Reproductive toxicity, Category 1B

    Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H315 Causes skin irritation

    H332 Harmful if inhaled

    H360 May damage fertility or the unborn child

    H400 Very toxic to aquatic life

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    P203 Obtain, read and follow all safety instructions before use.

    P273 Avoid release to the environment.

    Response

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P321 Specific treatment (see ... on this label).

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P317 Get medical help.

    P318 IF exposed or concerned, get medical advice.

    P391 Collect spillage.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Terbinafine hydrochloride,Carboplatin,Pramipexole dihydrochloride Monohydrate,Cisatracurium Besylate,Rivaroxaban,Lenvatinib

    Location:

    NO.28 SangYuan Rd,JinanCity,ShanDong Province,China

    Payment Terms:

    TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    1

    Total Annual Revenue:

    $50 million-$100 million

    Total Employees:

    501-1000

    Year of Establishment:

    2005

  • Inquiry History
    1 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    4-Amino-3-chlorophenol

    5 KG Mar 11, 2024
    Post an enquiry for this product
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