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Lenalidomide

Unit Price: Get Latest Price
CAS No.:

191732-72-6

Grade:

Industrial Grade

Content:

99%

Port:

beijing;SHANGHAI

Brand:

shandong boyuan

Packaging:

25kg/Cardboard Drum

Price valid (until):

2024-09-30

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Terbinafine hydrochloride,Carboplatin,Pramipexole dihydrochloride Monohydrate,Cisatracurium Besylate,Rivaroxaban,Lenvatinib

  • Product Description

  • Seller Information

  • Description

    enalidomide;Lenalidomid;Revlimid;3-(4-amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione,Lenalidomide;LenalidoMide(CC-5013,RevliMid);LenalChemicalbookidomide,98%;3-(4-amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione;(3S)-3-(4-Amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione

    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

    Lenalidomide is an immunomodulatory drug with multiple mechanisms of action. In in vitro studies, lenalidomide has three main effects: 1) direct anti-tumor effect 2) inhibition of angiogenesis 3) immune regulation . In vivo, lenalidomide induces tumor cell apoptosis directly or indirectly through inhibition of bone marrow stromal cell support, chemicalbook anti-angiogenic and anti-osteoclastic effects, and immunomodulatory activity. At the molecular level, lenalidomide has been shown to interact with ubiquitin E3 ligase and target this enzyme for degradation of the Ikaros transcription factors IKZF1 and IKZF3.

    Items Specifications
    storage Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    InChI InChI=1S/C13H13N3O3/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18/h1-3,10H,4-6,14H2,(H,15,17,18)
    solubility Soluble in DMSO (up to 30 mg/ml)
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    Basic Info
    Product Name:

    Lenalidomide

    Other Name:

    2,6-Piperidinedione,3-(4-amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-;3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione;3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione;Revimid;CC 5013;CDC 501;Lenalidomide;Revlimid;1-Oxo-4-amino-2-(2,6-dioxopiperidin-3-yl)isoindole;3-(4-Amino-1-oxoisoindolin-2-yl)piperidin-2,6-dione;ENMD 0997;IMiD 3;revlMiD;346670-73-3;443912-14-9;824975-68-0

    CAS No.:

    191732-72-6

    Molecular Formula:

    C13H13N3O3

    InChIKeys:

    InChIKey=GOTYRUGSSMKFNF-UHFFFAOYSA-N

    Molecular Weight:

    259.26062

    Exact Mass:

    259.26

    EC Number:

    1308068-626-2

    NSC Number:

    747972

    DSSTox ID:

    DTXSID8046664

    Color/Form:

    Off-white to pale-yellow solid powder

    ATC Code:

    L04AX04|L04AX|L - Antineoplastic and immunomodulating agents

    HScode:

    29339900

    Characteristics
    PSA:

    92.5

    XLogP3:

    -0.5

    Appearance:

    Solid

    Density:

    1.460±0.06 g/cm3(Predicted)

    Melting Point:

    269-271°C

    Boiling Point:

    614.0±55.0 °C(Predicted)

    Flash Point:

    325.1±31.5 °C

    Refractive Index:

    1.672

    Water Solubility:

    soluble in organic solvent/water mixtures, and buffered aqueous solvents. Lenalidomide is more soluble in organic solvents and low pH solutions. Solubility was significantly lower in less acidic buffers, ranging from about 0.4 to 0.5 mg/mL.

    Storage Conditions:

    -20°C Freezer

    Vapor Pressure:

    1.78X10-13 mm Hg at 25 deg C (est)

    Specific rotation:

    Has an asymmetric carbon atom and can exist as the optically active forms S(-) and R(+), and is produced as a reacemic mixture with a net optical rotation of zero

    Henrys Law Constant:

    Henry's law constant = 1.26X10-17 atm-cu m/mol at 25 °C (est)

    Dissociation Constants:

    pKa1 = 2.31 (primary amine); pKa2 = 11.61 (secondary amine) (est)

    Hazard Identification

    Classification of the substance or mixture

    Reproductive toxicity, Category 1B

    Specific target organ toxicity – repeated exposure, Category 1

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H360 May damage fertility or the unborn child

    H372 Causes damage to organs through prolonged or repeated exposure

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    Response

    P318 IF exposed or concerned, get medical advice.

    P319 Get medical help if you feel unwell.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Terbinafine hydrochloride,Carboplatin,Pramipexole dihydrochloride Monohydrate,Cisatracurium Besylate,Rivaroxaban,Lenvatinib

    Location:

    NO.28 SangYuan Rd,JinanCity,ShanDong Province,China

    Payment Terms:

    TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    1

    Total Annual Revenue:

    $50 million-$100 million

    Total Employees:

    501-1000

    Year of Establishment:

    2005

  • Country Product Purchase Quantity Date Posted
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