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Home > Active Pharmaceutical Ingredients > Other Chemical Drugs > Isotretinoin for Sale > Api Powder Isotretinoin 98% Accutane ISOTRETINOIN API POWDER
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Api Powder Isotretinoin 98% Accutane ISOTRETINOIN API POWDER

GMP HALAL 19 Inquiries

Unit Price: Get Latest Price
CAS No.:

4759-48-2

Grade:

Top Product

Content:

98%

Port:

Wuhan

Brand:

Senwayer

Packaging:

1KG per foil bag, 25KG per drum.

Price valid (until):

2023-03-24

Company Type:
Trader
Location:
China
Qualification:
Main Products:

API,nutrition supplements,plant extract,peptide,HCG,6-Aminocaproic acid

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail 


     



    MFC20H28O2
    MW300.44
    Boiling Point381.66°C (rough estimate)
    Density1.0597 (rough estimate)
    EINECS225-296-0
    NameIsotretinoin
    IntroductionIt belongs to the first generation of tretinoin and is the stereoisomer of all trans tretinoin. Oral administration has anti lipid effect and has special curative effect on severe acne. The mechanism of action is as follows: it can reduce the sebaceous glands, inhibit the activity of sebaceous glands, and reduce the secretion of sebaceous glands, so as to inhibit the reproduction of Propionibacterium acnes which depends on the growth of lipid environment. It has the effect of anti keratinization, inhibiting the excessive proliferation of epidermal cells and promoting their differentiation, and can reduce the keratinization of hair follicle mouth and sebaceous duct. It can also affect the function of monocytes and lymphocytes, inhibit the chemotaxis of neutrophils and has anti-inflammatory activity. It selectively binds to retinoic acid chemicalbook nuclear receptor and plays a therapeutic role. It can inhibit the proliferation of Corynebacterium acnes. It has the effect of immunostimulation at low dose and immunosuppression at high dose. It can inhibit the formation of collagenase and gelatinase in skin, and inhibit the activity of ornithine decarboxylase. The induction of ornithine decarboxylase can play a major role in skin mutation, so Accutane can also inhibit the occurrence of tumor. The mechanism of action of this product is similar to that of retinoic acid. It can induce the proliferation of epidermal cells, promote the differentiation of epidermal granular layer into stratum corneum, regulate the process of abnormal keratinization of hair follicle sebaceous epithelium, and play a therapeutic role.


    Certificates

    Basic Info
    Product Name:

    Isotretinoin

    Other Name:

    Retinoic acid,13-cis-;13-cis-Retinoic acid;Neovitamin A acid;13-cis-Vitamin A acid;Ro 4-3780;13-cis-β-Retinoic acid;Isotretinoin;(13Z)-Retinoic acid;Accutane;Roaccutane;AGN 190013;Roaccutan;Accure;13-RA;Isotrex;IsotrexGel;cis-Retinoic acid;Absorica;Amnesteem;Claravis;Roacutan

    CAS No.:

    4759-48-2

    Molecular Formula:

    C20H28O2

    InChIKeys:

    InChIKey=SHGAZHPCJJPHSC-XFYACQKRSA-N

    Molecular Weight:

    300.44

    Exact Mass:

    300.44

    EC Number:

    225-296-0

    HScode:

    2942000000

    Categories:

    Other Chemical Drugs

    Characteristics
    PSA:

    37.3

    XLogP3:

    5.66

    Appearance:

    Yellow-orange to orange Fine Crystalline Powder

    Density:

    1.0±0.1 g/cm3

    Melting Point:

    174-175 °C

    Boiling Point:

    462.8°C at 760 mmHg

    Flash Point:

    350.6±11.0 °C

    Refractive Index:

    1.556

    Water Solubility:

    H2O: insoluble

    Storage Conditions:

    −20°C

    Vapor Pressure:

    1.02X10-7 mm Hg at 25 °C (est)

    Toxicity:

    LD50 (20 day) in mice, rats (mg/kg): 904, 901 i.p.; 3389, >4000 orally (Kamm)

    PKA:

    ~4

    Hazard Identification

    Classification of the substance or mixture

    Reproductive toxicity, Category 1B

    Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H360 May damage fertility or the unborn child

    H400 Very toxic to aquatic life

    H410 Very toxic to aquatic life with long lasting effects

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P273 Avoid release to the environment.

    Response

    P318 IF exposed or concerned, get medical advice.

    P391 Collect spillage.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    PRECAUTIONS FOR CYTOTOXIC AND HAZARDOUS DRUGS:/ Facilities (eg, shelves, carts, counters, and trays) for storing hazardous drugs are designed to prevent breakage and to limit contamination in the event of leakage. Bins, shelves with barriers at the front, or other design features that reduce the chance of drug containers falling to the floor should be used. Hazardous drugs requiring refrigeration should be stored separately from nonhazardous drugs in individual bins designed to prevent breakage and to contain leakage.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    API,nutrition supplements,plant extract,peptide,HCG,6-Aminocaproic acid

    Location:

    Room 707, Block A, Zhongxing Times Digital Trade Port, No. 79 Xudong Street, Hongshan District, Wuhan City

    Payment Terms:

    TT against copy of documents,L/C

    Average lead Time:

    10

    Total Annual Revenue:

    $2.5 million-$5 million

    Total Employees:

    51-100

    Year of Establishment:

    2020

    Certifications:

    Verified supplier certificate,SGS

      Dingwang Technology (Wuhan) Co., Ltd located in the predominant WuHan City where is a traffic hinge of China,specilize in producing and developing pharmaceutical & its intermediates, Peptide, Nutritional supplements,food additive, Plant extracts,and in distributing the products of our own company and affiliated enterprises.
          We have set up R&D center, quality inspection center and manufacturing site in Wuhan, Jiangsu and others places.

    Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. Meanwhile, we possess of complete Q.A. and Q.C. system, supply chemical products with good quality and custom-tailored products according to our clients' requirement.
           We have professional sales team, focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market , our products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc.
         With our constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.
  • Inquiry History
    19 Inquiries
    Country Product Purchase Quantity Date Posted
    Croatia

    Isotretinoin 4759-48-2

    10 G Nov 18, 2023
    United States

    isotretinoin

    1 KG Apr 8, 2026
    Canada

    Isotretinoin

    50 G Feb 19, 2026
    United States

    Isotretinoin

    100 G Jan 27, 2026
    Czech

    Isotretinoin

    30 G Dec 17, 2025
    Russia

    Isotretinoin Lidose 8 mg, 16 mg, 24 mg, 32 mg

    500 KG Nov 13, 2025
    Czech

    Isotretinoin

    1 KG Nov 8, 2025
    Pakistan

    Isotretinoin

    10000 MG Oct 25, 2025
    Norway

    Isotretinoin powder

    10 G Apr 13, 2025
    Germany

    Api Powder Isotretinoin 98% Accutane ISOTRETINOIN API POWDER

    10 G Apr 3, 2026
    Australia

    isotretinoin

    10 G Mar 10, 2026
    United States

    Isotretinoin

    1 MT Mar 5, 2026
    Denmark

    Isotretinoin powder

    20 G Nov 21, 2025
    Pakistan

    Isotretinoin

    1 KG Oct 27, 2025
    United States

    Isotretinoin

    1 KG Sep 2, 2024
    United States

    Isotretinoin

    10 G Jul 8, 2023
    France

    High purity isotretinoin powder for cystic acne

    10 G Nov 3, 2024
    Pakistan

    isotretranin

    200 KG Oct 17, 2024
    Ireland

    Isotretinoin powder

    1 KG Feb 28, 2024
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