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Api Phentolamine mesilate powder 98% Phentolamine mesylate Phentolamine methanesulfonate buy - image1

Api Phentolamine mesilate powder 98% Phentolamine mesylate Phentolamine methanesulfonate

Name: Api Phentolamine mesilate powder 98% Phentolamine mesylate Phentolamine methanesulfonate
Brand: Senwayer
SKU: pr2203293138
Price: 1.5 USD
Availability: InStock

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CAS No.:

65-28-1

Grade:

Top Product

Content:

98%

Port:

Wuhan

Brand:

Senwayer

Packaging:

1KG per foil bag, 25KG per drum.

Price valid (until):

2024-04-29

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Dingwang Technology (Wuhan) Co., Ltd.

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,L/C

Average Lead Time:

10 days

Qualification:

Main Products:

API,nutrition supplements,plant extract,peptide,HCG,6-Aminocaproic acid

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Product Description
Seller Information
Inquiry History

Description

Product Detail

MF	C18H23N3O4S
MW	377.46
Melting Point	180-182 °C(lit.)
Density	1.2256 (rough estimate)
EINECS NO.	200-604-6
Introduction	This product is an α-receptor blocker. By blocking the α-receptor and indirectly activating the β-receptor, the peripheral blood vessels can be rapidly dilated, the peripheral vascular resistance can be significantly reduced, the peripheral blood volume can be increased, and the microcirculation can be improved. This product has an exciting effect on the heart, resulting in increased myocardial contractility, accelerated heart rate and increased cardiac output. It is mainly used in the diagnosis of acute heart failure, vasospasm, hand and foot cyanosis, perceptual toxic shock and pheochromocytoma in the treatment of pulmonary hyperemia or pulmonary edema. It is also used for ventricular extrasystole.
Function	Phentolamine mesilate is A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive.

ECHEMI Editorial Reference

Phentolamine mesylate is a competitive, reversible α-adrenoceptor antagonist with an IC50 between 5 and 30 nM.
Phentolamine Mesylate is the mesylate salt of a synthetic imidazoline with alpha-adrenergic antagonist activity. As a competitive alpha-adrenergic antagonist, phentolamine binds to alpha-1 and alpha-2 receptors, resulting in a decrease in peripheral vascular resistance and vasodilatation. This agent also may block 5-hydroxytryptamine (5-HT) receptors and stimulate release of histamine from mast cells.|A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.

Certificates

Basic Info

Product Name:

Phentolamine methanesulfonate

Other Name:

Phenol,3-[[(4,5-dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino]-,methanesulfonate (1:1);Phenol,m-[N-(2-imidazolin-2-ylmethyl)-p-toluidino]-,monomethanesulfonate (salt);Phenol,3-[[(4,5-dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino]-,monomethanesulfonate (salt);m-[N-(2-Imidazolin-2-ylmethyl)-p-toluidino]phenol methanesulfonate;Phentolamine mesylate;Phentolamine methanesulfonate;Regitine methanesulfonate;Regitin methanesulphonate;Phentolamine methanesulphonate;Regitine mesylate;Vasomax;Rogitine;252228-09-4

CAS No.:

65-28-1

Molecular Formula:

C17H19N3O.CH4O3S

InChIKeys:

InChIKey=OGIYDFVHFQEFKQ-UHFFFAOYSA-N

Molecular Weight:

377.46

Exact Mass:

377.140930

EC Number:

200-604-6

UNII:

Y7543E5K9T

DSSTox ID:

DTXSID60215315

NCI Thesaurus Code:

C38691

HScode:

2933290090

Categories:

Other Chemical Drugs

Characteristics

PSA:

111

Appearance:

white to off-white powder

Density:

1.2256 (rough estimate)

Melting Point:

177-181 °C

Boiling Point:

551°C at 760 mmHg

Flash Point:

287ºC

Water Solubility:

H2O: 50 mg/mL;ethanol: 26 mg/mL

Storage Conditions:

Refrigerator

Toxicity:

LDLo scu-rat: 275 mg/kg NIIRDN 6,667,82

See More Phentolamine methanesulfonate Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Acute toxicity - Category 4, Dermal

Skin irritation, Category 2

Eye irritation, Category 2

Acute toxicity - Category 4, Inhalation

Specific target organ toxicity â single exposure, Category 3

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed H312 Harmful in contact with skin H315 Causes skin irritation H319 Causes serious eye irritation H332 Harmful if inhaled H335 May cause respiratory irritation
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P317 Get medical help. P321 Specific treatment (see ... on this label). P362+P364 Take off contaminated clothing and wash it before reuse. P332+P317 If skin irritation occurs: Get medical help. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P319 Get medical help if you feel unwell.
Storage	P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Phentolamine methanesulfonate Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
API,nutrition supplements,plant extract,peptide,HCG,6-Aminocaproic acid

Location:
Room 707, Block A, Zhongxing Times Digital Trade Port, No. 79 Xudong Street, Hongshan District, Wuhan City

Payment Terms:
TT against copy of documents,L/C

Average lead Time:
10 days

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
51-100

Year of Establishment:
2020

Company Certificates
- Verified supplier certificate
- SGS
Dingwang Technology (Wuhan) Co., Ltd located in the predominant WuHan City where is a traffic hinge of China,specilize in producing and developing pharmaceutical & its intermediates, Peptide, Nutritional supplements,food additive, Plant extracts,and in distributing the products of our own company and affiliated enterprises.
We have set up R&D center, quality inspection center and manufacturing site in Wuhan, Jiangsu and others places.
Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. Meanwhile, we possess of complete Q.A. and Q.C. system, supply chemical products with good quality and custom-tailored products according to our clients' requirement.
We have professional sales team, focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market , our products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc.
With our constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.

Inquiry History

5 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	Phentolamine Mesylate	1 G	Oct 25, 2024
Thailand	Phentolamine Mesylat	100 G	Apr 13, 2026
United States	Phentolamine Mesylate	1 G	Oct 26, 2024
United States	PGE1	1 G	Feb 11, 2025
United States	Papaverine HCl	100 G	Jan 23, 2024

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Api Phentolamine mesilate powder 98% Phentolamine mesylate Phentolamine methanesulfonate

Product Description

Seller Information