Phentolamine mesilate, OraVerse 99% white powder 65-28-1 Senwayer

Phentolamine Mesylate for is an antihypertensive indicated for the prevention or control of hypertensive (high blood pressure) episodes that may occur in a patient with pheochromocytoma as a result of stress or manipulation during preoperative preparation and surgical excision, for the prevention or treatment of dermal necrosis and sloughing following intravenous administration or extravasation of norepinephrine, and for the diagnosis of pheochromocytoma by the phentolamine blocking test. Phentolamine mesylate is available in generic form.

Phentolamine mesylate (OraVerse), a nonselective a-adrenergic blocking drug, is the first therapeutic agent marketed for the reversal of soft-tissue anaesthesia and the associated functional deficits resulting from an intraoral submucosal injection of a local anaesthetic containing a vasoconstrictor.

Common side effects of phentolamine mesylate for injection include:

• acute and prolonged hypotensive episodes
• fast heart rate
• cardiac arrhythmias
• 
• weakness
• dizziness
• flushing
• 
• dizziness upon standing (orthostatic hypotension)
• stuffy nose
• 
• nausea
• vomiting
• diarrhea

Phentolamine works by blocking alpha receptors in certain parts of the body. Alpha receptors are present in the muscle that lines the walls of blood vessels. When the receptors are blocked by Phentolamine, the muscle relaxes and the blood vessels widen.

Wuhan senwayer century chemical Co.,Ltd located in the predominant WuHan City where is a traffic hinge of China,specilize in producing and developing pharmaceutical & its intermediates, Pesticide Intermediate, food additive, Plant extracts,and in distributing the products of our own company and affiliated enterprises.

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