Fexofenadine hydrochloride
6 Inquiries
153439-40-8
industrial Grade
98%
SHANGHAI
KieRay Chem
25kg/drum
2022-12-31
fine chemicals,pharmaceutical materials
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceOff-White Crystalline SolidFexofenadine hydrochloride (trade name: Allegra) belongs to a second-generation antihistamine pharmaceutical drug. It is mainly used for the treatment of allergy symptoms including watery eyes, hay fever, nasal congestion, urticaria, runny nose, itching eyes/nose, sneezing, hives, and itching. It is a kind of selectively peripheral H1 blocker. Its mechanism of action in vivo is through preventing the histamine-mediated activation of the H1 receptors, thus alleviating
Fexofenadine hydrochloride is a diarylmethane.|Fexofenadine is a second generation antihistamine that is used for the treatment of allergic rhinitis, angioedema and chronic urticaria. Fexofenadine has not been linked to serum enzyme elevations during therapy or to instances of clinically apparent acute liver injury.|Fexofenadine Hydrochloride is the hydrochloride salt form of fexofenadine, a carboxylated metabolic derivative of terfenadine and second generation, long-lasting selective histamine H1 receptor antagonist, with antihistaminic activity. Upon administration, fexofenadine competitively binds of peripheral H1-receptors in the gastrointestinal (GI) tract, blood vessels, and bronchial smooth muscle. This prevents binding of histamine to peripheral H1-receptors and prevents their activation. This prevents a histamine-mediated allergic reaction. Fexofenadine does not cross the blood-brain-barrier (BBB).Basic Info-
Product Name:
Fexofenadine hydrochloride
Other Name:Benzeneacetic acid,4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dimethyl-,hydrochloride (1:1);Benzeneacetic acid,4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dimethyl-,hydrochloride;MDL 16455A;Fexofenadine hydrochloride;Allegra;Telfast;Telfast BD;Alernex;Fexo;Fexofen;Feksine;Fexadyne;Vivafeks;Fastofen;Fexodine;Rapido;2-(4-[1-Hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl]phenyl)-2-methylpropanoic acid hydrochloride;138452-21-8
CAS No.:153439-40-8
Molecular Formula:C32H39NO4.ClH
InChIKeys:InChIKey=RRJFVPUCXDGFJB-UHFFFAOYSA-N
Molecular Weight:538.12
Exact Mass:537.265
EC Number:1308068-626-2
NSC Number:758678
DSSTox ID:DTXSID5048716
NCI Thesaurus Code:C29050
HScode:2933399090
Categories:
Characteristics-
PSA:
81
Appearance:white to beige
Melting Point:148-150oC
Water Solubility:Soluble in Dimethyl sulfoxide (50 mM), and methanol.
Storage Conditions:−20°C
Hazard IdentificationClassification of the substance or mixture
Skin sensitization, Category 1
Reproductive toxicity, Category 1B
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Danger
Hazard statement(s) H317 May cause an allergic skin reaction
H360 May damage fertility or the unborn child
Precautionary statement(s) Prevention P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P203 Obtain, read and follow all safety instructions before use.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P333+P317 If skin irritation or rash occurs: Get medical help.
P321 Specific treatment (see ... on this label).
P362+P364 Take off contaminated clothing and wash it before reuse.
P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
fine chemicals,pharmaceutical materials
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Location:
Room 260, Building 3, No. 76 Xingqiao North Road, Xingqiao Street, Yuhang District, Hangzhou City, Zhejiang Province, China
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Payment Terms:
TT against copy of documents,L/C
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Total Employees:
11-50
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Year of Establishment:
2020
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Inquiry History6 Inquiries
Country Product Purchase Quantity Date Posted
Bangladesh
Fexofenadine HCI
1500 KG Dec 9, 2025
Bangladesh
Fexofenadine hydrochloride
650 KG Nov 14, 2024
Bangladesh
Fexofenadine HCL USP
1500.00 KG Nov 10, 2023
Bangladesh
Fexofenadine HCI
1500.00 KG Dec 11, 2025
India
Fexofenadine hcl.
2.00 TON May 8, 2025
India
Fexofenadine Hydrochloride
1 MT Apr 4, 2025 Post an enquiry for this product


