Moxonidine
75438-57-2
industrial Grade
98%
SHANGHAI
KieRay Chem
25kg/drum
Yes
2022-12-31
fine chemicals,pharmaceutical materials
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceMoxonidine(BDF5895) is a selective agonist at the imidazoline receptor subtype 1, used as antihypertensive agent.Target: I1-RMoxonidine is a centrally acting antihypertensive agent. Mixed Nischarin (I1 imidazoline receptor) and α2-AR (adrenergic) agonist; displays 40-fold higher affinity for I1 receptors versus α2-adrenoceptors. Moxonidine reduced stimulated NE overflow (log EC50: -6.15 +/- 0.14). AGN192403, a selective ligand at I1-R, had no influence on the dose-response curve of moxon
Moxonidine is an organohalogen compound and a member of pyrimidines.|Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild to moderate essential hypertension. It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and calcium channel blockers are not appropriate or irresponsive. As well, moxonidine has been shown to present blood pressure-independent beneficial effects on insulin resistance syndrome.Basic Info-
Product Name:
Moxonidine
Other Name:5-Pyrimidinamine,4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-;4-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamine;BE 5895;Moxonidine;BDF 5895;2-(6-Chloro-4-methoxy-2-methylpyrimidin-5-ylamino)-2-imidazoline;Cynt;Lomox;Moxon;Normoxocin;Physiotens;LY 326869;Nucynt;Norcynt;Moxogamma;(4-Chloro-6-methoxy-2-methyl-pyrimidin-5-yl)-imidazolidin-2-ylidene-amine;257301-50-1
CAS No.:75438-57-2
Molecular Formula:C9H12ClN5O
InChIKeys:InChIKey=WPNJAUFVNXKLIM-UHFFFAOYSA-N
Molecular Weight:241.68
Exact Mass:241.68
EC Number:1308068-626-2
UNII:CC6X0L40GW
DSSTox ID:DTXSID5045170
ATC Code:C02AC05|C - Cardiovascular system
Categories:
Characteristics-
PSA:
71.4
XLogP3:0.6
Appearance:crystal
Density:1.5±0.1 g/cm3
Melting Point:217-219 °C (decomp)
Boiling Point:364.7°C at 760 mmHg
Flash Point:174.3±30.7 °C
Refractive Index:1.681
Water Solubility:800.3mg/L(temperature not stated)
Storage Conditions:Desiccate at +4°C
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 3, Oral
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H301 Toxic if swallowed
H411 Toxic to aquatic life with long lasting effects
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P391 Collect spillage.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
fine chemicals,pharmaceutical materials
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Location:
Room 260, Building 3, No. 76 Xingqiao North Road, Xingqiao Street, Yuhang District, Hangzhou City, Zhejiang Province, China
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Payment Terms:
TT against copy of documents,L/C
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Average lead Time:
15 days
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Total Annual Revenue:
$1 million-$2.5 million
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Total Employees:
11-50
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Year of Establishment:
2020
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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