Mots-c 99% white powder 1627580-64-6 Senwayer

MOTS-c is a relatively new peptide of 16 amino acids that promote metabolic balance. It regulates metabolic functions throughout the body. For instance, it turns glucose into usable energy.

The DNA in the cell nucleus encodes most peptides. But, the mitochondria’s DNA encodes MOTS-c making it unique among peptides.

MOTS-c has a long list of possible benefits. Most notably, it may improve physical function, insulin sensitivity, age-related metabolic diseases, and obesity.

Improves Physical Function

One of the signs of aging is the gradual loss of cell function. In turn, this inhibits the working tissue of organs and leads to less physical ability. As a result, aging is the leading risk for chronic disease.

We link aging with reduced MOTS-c levels in many tissues, including skeletal muscle and circulation.

According to study results, MOTS-c treatment helped middle-aged and old mice run significantly longer and further than untreated mice. What’s more, old mice outperformed untreated middle-aged mice. The results suggest physical re-programming rather than just rejuvenation.

In other words, MOTS-c seems to increase exercise ability on a cellular level.

Controls Insulin Sensitivity

MOTS-c may also improve whole-body insulin sensitivity.

When there’s more glucose available, insulin helps distribute it. It also inhibits hepatic glucose production (HGP) to help the body maintain balance.

As the body becomes less sensitive to insulin, it doesn’t use it as well, which increases the risk of type 2 diabetes.

Researchers noted the peptide helped the body distribute insulin faster, showing better skeletal muscle insulin sensitivity.

Because MOTS-c boosts insulin sensitivity, it may help the body use insulin better and lower the risk of insulin resistance.

Metabolic Diseases of Aging

We associate aging with a decline of mitochondrial function and developing age-related diseases, such as diabetes and metabolic syndrome. And since MOTS-c levels fall with age, declining mitochondrial-derived peptides (MDP) may relate to metabolic decline.

Thus, regular MDP treatments may improve the abnormal metabolism linked with aging in humans.

Helps With Diet-induced Obesity

The peptide may affect obesity, as well.

The peptide helps activate AMPK in mice on a high-fat diet. For this reason, it may prevent diet-induced obesity.

What is AMPK? The AMP-activated protein kinase (AMPK) acts as a cellular energy sensor. Cells activate AMPK when they are running low on energy. It’s also activated throughout the body after exercise or during calorie restriction. Studies show that compounds that activate AMPK may promote health. For instance, it may reverse diabetes, enhance heart health, treat mitochondrial diseases, and even increase life span.

The mice also used oxygen and glucose more efficiently and generated more heat. As a result, they burned more energy.

The study suggests that MOTS-c may prevent diet-induced obesity because it increases energy use and heat production and improves insulin sensitivity and glucose use.

While the peptide didn’t seem to affect body weight with regular diets, it can support weight loss in some cases.

Other Benefits

In addition to the benefits mentioned, it may also:

• Promote fatty acid metabolism in the liver
• Help control mitochondrial energy
• Promote metabolic flexibility and balance
• Improve resistance to metabolic stress
• Help prevent osteoporosis

To my knowledge, MOTS-C is very safe and has not been proven to have any side effects.

This has been confirmed by a health clinic in Springfield, Missouri that frequently uses MOTS-C as a part of their “accelerated fitness programs”

Then again, the MOTS-C peptide has yet to be clinically studied in human subjects (as you saw earlier, all of the available studies are done on either mice or cell cultures).

The very few biohackers who have attempted to experiment with MOTS-C report some of the following side effects

• Sharp pain at the site of injection that lasts several hours (sometimes solved by switching to intramuscular injections instead)
• Possible promotion of cancer cell growth (this is 100% SPECULATIVE and has not been proven)

Based on my limited experience with using MOTS-C, I can confidently say the following…

Some people respond well to it, but those who are leaner and have stronger (i.e. more up-regulated) mitochondrial activity usually don’t.

At the end of the day, biochemical individuality is always the ultimate determinant for whether you will respond effectively to MOTS-C. 

Wuhan senwayer century chemical Co.,Ltd located in the predominant WuHan City where is a traffic hinge of China,specilize in producing and developing pharmaceutical & its intermediates, Pesticide Intermediate, food additive, Plant extracts,and in distributing the products of our own company and affiliated enterprises.

We have set up R&D center, quality inspection center and manufacturing site in Wuhan, Jiangsu and others places.
Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. Meanwhile, we possess of complete Q.A. and Q.C. system, supply chemical products with good quality and custom-tailored products according to our clients' requirement.
We have professional sales team, focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market , our products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc.

With our constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.

If you are interested, pls contact me freely!