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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > N-Acetyl-L-cysteine for Sale > N-acetylcysteine, NAC, N-Acetyl-L-cysteine 99% white powder 616-91-1 Senwayer
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N-acetylcysteine, NAC, N-Acetyl-L-cysteine 99% white powder 616-91-1 Senwayer

TDS 20 Inquiries

Unit Price: Get Latest Price
CAS No.:

616-91-1

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Brand:

Senwayer

Packaging:

500g/ bag 25kg/ drum

Price valid (until):

2023-05-12

Company Type:
Trader
Location:
China
Qualification:
Main Products:

API,nutrition supplements,plant extract,peptide,HCG,6-Aminocaproic acid

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Introduction  


    N-Acetyl L-Cysteine (NAC or N-acetylcysteine) is the N-acetyl derivative of the naturally occurring amino acid L-cysteine. And works primarily by helping restore the body’s natural antioxidant glutathione (γ-glutamylcysteinylglycine; GSH).

    Product nameN-Acetyl-L-cysteine
    CAS No.616-91-1
    MFC5H9NO3S
    MW163.19
    EINECS No.210-498-3
    Melting point106-108 °C(lit.)
    Boiling point407.7±40.0 °C(Predicted)
    Density1.249 (estimate)
    Storage2-8°C
    SolubilityH2O: 100 mg/mL with heating



      Product Uses  


    People commonly use N-acetyl cysteine for cough and other lung conditions. It is also used for fludry eye, and many other conditions, but there is no good scientific evidence to support many of these uses. There is also no good evidence to support using N-acetyl cysteine for COVID-19.


      Product Function & Benefits


    Kidney and Liver Detoxification

    N-acetyl L-cysteine plays a vital role to detoxify the kidney and liver. It has been proven to help combat the negative side effects of various pharmaceuticals as well as combat toxins from the natural environment. Patients who have overdosed on certain drugs such as Tylenol or paracetamol can be treated with NAC to limit liver and kidney damage.

    Antioxidant Production

    N-acetyl L-cysteine paired with glutamine and glycine plays an important role in the replacement of glutathione. This is one of the most important antioxidants that your body produces naturally. Glutathione helps to neutralize the free radicals that cause damage to various tissues and cells in the body. It helps boost your immune system and may even increase your lifespan.

    Mental Health


    Glutamate is the most important neurotransmitter in the brain. It is essential in order to have a normal level of brain function. If there is too much glutamate in the brain but not enough glutathione, the brain is in danger of becoming damaged. N-acetyl L-cysteine helps to ensure that the level of glutamate remains steady by regulating those levels. Properly regulating glutamate levels may help reduce addictive behaviors such as obsessive-compulsive disorder (OCD). It has also shown promise in reducing the symptoms of schizophrenia, depression and bipolar disorder. In the case of those addicted to brain-altering substances, NAC has been proven to help reduce the severity of withdrawal symptoms.

    Fertility


    N-acetyl L-cysteine helps guard against several illnesses that develop from oxidative stress. One of the main causes of infertility is oxidative stress. Many infertility issues in men can be linked to insufficient antioxidant levels. Antioxidants are extremely important when it comes to reducing the effects of oxidative stress in the reproductive system. When the body is low in this vital amino acid, it can result in infertility. Studies have proven that supplementing with a regular dose of NAC and selenium has a positive effect on fertility. Women who suffer from polycystic ovary syndrome (PCOS) often have trouble with fertility. Supplementing with NAC helps stimulate ovulation.

    Skin


    As we age, our bodies produce less antioxidants that help prevent cell damage. NAC is an effective way to supplement these vital antioxidants externally to reduce signs of aging, either orally or topically. It may help reduce acne, brighten and firm the skin or encourage skin cell regeneration.

    Brain Function


    NAC supplements help boost brain health by regulating glutamate levels in the body. This essential neurotransmitter is tied to memory, learning and behavior. It also helps to decrease oxidative damage to the brain cells, which is a result of the aging process. Patients who suffer from various memory issues or brain ailments may benefit from supplementing with NAC. Oxidative damage severely affects people who suffer from Alzheimer’s disease and Parkinson’s disease. NAC has shown progress in reducing the symptoms of these diseases.

    Stabilizes Blood Sugar


    Inflammation in adipose tissue has been closely linked to obesity and high blood sugar levels. When left untreated, this can damage or destroy the insulin receptors in the body. Faulty insulin receptors increase the chances of developing type 2 diabetes. Preliminary studies have shown that N-acetyl L-cysteine helps reduce fat cell inflammation, which in turn helps improve insulin resistance and stabilizes blood sugar.

    Respiratory Health


    N-acetyl L-cysteine can treat several respiratory conditions. It benefits the lungs as an expectorant, which helps loosen thick mucus. It also increases glutathione levels in the lungs and bronchial tubes, which works to reduce inflammation and thin mucus. Studies have shown that supplementing with NAC may help improve the symptoms of COPD and improve lung function in the process. This reduces coughing, wheezing and various respiratory attacks. Patients suffering from asthma, bronchitis, pulmonary fibrosis and cystic fibrosis have found relief with supplementation.

    Immune Function


    N-acetyl L-cysteine along with glutathione has been proven to help boost the immune system. In certain patients who are immuno-compromised, NAC has been shown to hinder virus replication. This helps to decrease the severity and duration of the illness. Similar studies have shown that NAC may block certain cancer cell replication.


      Product Side Effects  


    When taken by mouth: N-acetyl cysteine is likely safe for most adults. N-acetyl cysteine is an FDA-approved prescription drug. It can cause side effects such as dry mouth, nausea, vomiting, and diarrhea. It has an unpleasant odor that some people find hard to tolerate.

    When inhaled: N-acetyl cysteine is likely safe for most adults, when used as a prescription medication. It can cause swelling in the mouth, runny nose, drowsiness, clamminess, and chest tightness.


      About us  


    Wuhan senwayer century chemical Co.,Ltd located in the predominant WuHan City where is a traffic hinge of China,specilize in producing and developing pharmaceutical & its intermediates, Pesticide Intermediate, food additive, Plant extracts,and in distributing the products of our own company and affiliated enterprises.

    We have set up R&D center, quality inspection center and manufacturing site in Wuhan, Jiangsu and others places.
    Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. Meanwhile, we possess of complete Q.A. and Q.C. system, supply chemical products with good quality and custom-tailored products according to our clients' requirement.
    We have professional sales team, focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market , our products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc.

    With our constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.

    If you are interested, pls contact me freely!

    ECHEMI Editorial Reference
    Acetylcysteine is a mucolytic agent which reduces the thickness of the mucus.
    Solid
    N-acetyl-L-cysteine is an N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine. It has a role as an antiinfective agent, an antioxidant, an antiviral drug, an antidote to paracetamol poisoning, a vulnerary, a mucolytic, a human metabolite, a radical scavenger, a ferroptosis inhibitor and a geroprotector. It is a L-cysteine derivative, an acetylcysteine and a N-acetyl-L-amino acid. It is a conjugate acid of a N-acetyl-L-cysteinate.|Acetylcysteine (also known as N-acetylcysteine or N-acetyl-L-cysteine or NAC) is primarily used as a mucolytic agent and in the management of acetaminophen poisoning. It is a derivative of cysteine with an acetyl group attached to the amino group of cysteine. NAC is essentially a prodrug that is converted to cysteine (in the intestine by the enzyme aminoacylase 1) and absorbed in the intestine into the blood stream. Cysteine is a key constituent to glutathione and hence administration of acetylcysteine replenishes glutathione stores. Acetylcysteine can also be used as a general antioxidant which can help mitigate symptoms for a variety of diseases exacerbated by reactive oxygen species (ROS). For instance, acetylcysteine is commonly used in individuals with renal impairment to prevent the precipitation of acute renal failure. Acetylcysteine has been shown to have efficacy in treating mild to moderate traumatic brain injury including ischemic brain injury, particularly in reducing neuronal losses, and also reducing cognitive and neurological symptoms when administered promptly after injury. N-acetylcysteine is now widely used in the treatment of HIV, and it has reported efficacy in chronic obstructive pulmonary disease and contrast-induced nephropathy. Acetylcysteine is also being successfully used to treat a variety of neuropsychiatric and neurodegenerative disorders including cocaine, cannabis, and smoking addictions, Alzheimer's and Parkinson's diseases, autism, compulsive and grooming disorders, schizophrenia, depression, and bipolar disorder. Recent data also shows that N-acetylcysteine inhibits muscle fatigue and can be used to enhance performance in endurance events and in exercise and endurance training. Acetylcysteine is also undergoing clinical trials as RK-0202, an oral rinse for the prevention and treatment of mucositis. It is comprised of acetylcysteine in a polymer matrix.|Acetylcysteine is an Antidote, and Antidote for Acetaminophen Overdose, and Mucolytic. The mechanism of action of acetylcysteine is as a Reduction Activity. The physiologic effect of acetylcysteine is by means of Decreased Respiratory Secretion Viscosity, and Increased Glutathione Concentration.|Acetylcysteine, also known as N-acetylcysteine (NAC), is a modified amino acid that is used as an antidote for acetaminophen overdose to prevent hepatic injury. Acetylcysteine is a hepatoprotective agent and has not been linked to significant serum enzyme elevations during therapy or to instances of clinically apparent acute liver injury.|Acetylcysteine is a synthetic N-acetyl derivative and prodrug of the endogenous amino acid L-cysteine, a precursor of the antioxidant glutathione (GSH), with mucolytic, antioxidant, and potential cytoprotective, cancer-preventive, and anti-inflammatory activities. Upon administration, acetylcysteine exerts its mucolytic activity by reducing disulfide bonds in mucoproteins, resulting in liquification of mucus and reducing its viscosity. It is also used for the treatment of acetaminophen overdose as it can restore the depleted GSH reserves in the hepatocytes during the process of detoxification. The antioxidant activity is attributed to the ability of GSH to scavenge reactive oxygen species (ROS), thereby preventing ROS-mediated cell damage, decreasing oxidative stress, protecting cells against the damaging effects of free radicals and preventing apoptosis in these cells. In addition, this may inhibit tumor cell proliferation, progression and survival, in susceptible tumor cells that rely on ROS-mediated signaling for their proliferation and malignant behavior. Under certain circumstances, acetylcysteine is able to induce apoptosis in susceptible cells, including certain tumor cells, via the intrinsic mitochondria-dependent pathway but not involving endoplasmic reticulum stress. Also, acetylcysteine may also be able to degrade Notch2, thereby preventing proliferation, migration, and invasion in Notch2-overexpressing glioblastoma cells. In addition, acetylcysteine may inhibit viral stimulation by reactive oxygen intermediates, thereby producing antiviral activity in HIV patients. Acetylcysteine also possesses anti-inflammatory activity through modulation of the nuclear factor-kappa B (NF-kB) pathway and the modulation of cytokine synthesis.|The N-acetyl derivative of CYSTEINE. It is used as a mucolytic agent to reduce the viscosity of mucous secretions. It has also been shown to have antiviral effects in patients with HIV due to inhibition of viral stimulation by reactive oxygen intermediates.

    Certificates
    • N-acetylcysteine, NAC, N-Acetyl-L-cysteine 99% white powder 616-91-1 Senwayer Certificates 1 TDS

    Basic Info
    Product Name:

    N-Acetyl-L-cysteine

    Other Name:

    L-Cysteine,N-acetyl-;Cysteine,N-acetyl-,L-;N-Acetyl-L-cysteine;N-Acetylcysteine;Acetylcysteine;Mercapturic acid;Mucomyst;Mercapturic acid,(R)-;Airbron;Fluimucil;Fluimucetin;Respaire;Mucolyticum-Lappe;L-Acetylcysteine;Parvolex;Mucolytikum Lappe;Broncholysin;NSC 111180;Broncholysin (mucolytic);Mucosolvin;N-Acetyl-(R)-cysteine;Mucofilin;L-N-Acetylcysteine;Fluimicil;Fluimicil Infantil;Fluibiotic;Nα-Acetylcysteine;Exomuc;(R)-N-Acetylcysteine;Tixair;Muco Sanigen;Brunac;Fluatox;Mucocedyl;Mucolator;Neo-Fluimucil;Fabrol;Mucolyticum;Mucret;Fluprowit;Acetilcysteina;ACC;Flumil;Syntemucol;Hypotears;Lysomucil;Fluimucil Antidot;Acetadote;Mucosten;Asist;Trom;Mentopin;Mucomelt;Mucinac;(2R)-2Acetamido-3-sulfanylpropanoic acid;Cysteplus;Ac-Cys-OH;(2R)-2-Acetamido-3-sulfanylpropanoic acid;7696-05-1;1261105-20-7

    CAS No.:

    616-91-1

    Molecular Formula:

    C5H9NO3S

    InChIKeys:

    InChIKey=PWKSKIMOESPYIA-BYPYZUCNSA-N

    Molecular Weight:

    163.19

    Exact Mass:

    163.19

    BRN:

    1724426

    EC Number:

    210-498-3

    UNII:

    WYQ7N0BPYC

    DSSTox ID:

    DTXSID5020021

    NCI Thesaurus Code:

    C200

    Color/Form:

    Crystals from water|WHITE, CRYSTALLINE POWDER

    ATC Code:

    R05CB01|R - Respiratory system|S - Sensory organs|V - Various

    HScode:

    29309016

    Characteristics
    PSA:

    67.4

    XLogP3:

    0.4

    Appearance:

    White Solid

    Density:

    1.3±0.1 g/cm3

    Melting Point:

    109.5 °C

    Boiling Point:

    407.7°C at 760 mmHg

    Flash Point:

    200.4±27.3 °C

    Refractive Index:

    1.519

    Water Solubility:

    soluble in water, ethanol, methanol, dimethyl sulfoxide, hot isopropyl alcohol, methyl acetate and ethyl acetate. Insoluble in chloroform and ether.H2O: 100 mg/mL with heating

    Storage Conditions:

    2-8°C

    Vapor Pressure:

    1.1X10-5 mm Hg at 25 deg C /Estimated/

    Toxicity:

    Oral-rat LD50:5050 mg/kg; Oral-Mouse LD50:7888 mg/kg

    Flammability characteristics:

    Decomposes smoke in humid air; burning releases toxic nitrogen oxide and sulfur oxide smoke

    Specific rotation:

    -35.1 ºC (c=2,H2O)

    Odor:

    SLIGHT ACETIC ODOR

    Taste:

    CHARACTERISTIC SOUR TASTE

    PH:

    2 TO 2.75 (1 IN 100 ML)

    PKA:

    9.52(at 25 °C)

    Henrys Law Constant:

    Henry's Law constant = 1.7X10-13 atm-cu m/mole at 25 °C /Estimated/

    Dissociation Constants:

    9.52 (at 25 °C)|pKa= 3.24 (carboxylic acid moiety)|pKa = 9.52 (SH group)

    Collision Cross Section:

    140.9 Ų [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|140.9 Ų [M+Na]+

    Experimental Properties:

    It is stable in ordinary light, nonhygroscopic (oxidizes in moist air), and stable at temperatures up to 120 °C|Hydroxyl radical reaction rate constant = 5.5X10-11 cu cm/molec-sec at 25 °C /Estimated/

    Hazard Identification

    Classification of the substance or mixture

    Not classified.

    GHS label elements, including precautionary statements

    Pictogram(s) No symbol.
    Signal word

    No signal word

    Hazard statement(s)

    none

    Precautionary statement(s)
    Prevention

    none

    Response

    none

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Unopened vials of acetylcysteine sodium solution should be stored at 15-30 deg C. Following exposure to air, solutions should be stored at 2-8 deg C to retard oxidation and should be used within 96 hr.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    API,nutrition supplements,plant extract,peptide,HCG,6-Aminocaproic acid

    Location:

    Room 707, Block A, Zhongxing Times Digital Trade Port, No. 79 Xudong Street, Hongshan District, Wuhan City

    Payment Terms:

    TT against copy of documents,L/C

    Average lead Time:

    10

    Total Annual Revenue:

    $2.5 million-$5 million

    Total Employees:

    51-100

    Year of Establishment:

    2020

    Certifications:

    Verified supplier certificate,SGS

      Dingwang Technology (Wuhan) Co., Ltd located in the predominant WuHan City where is a traffic hinge of China,specilize in producing and developing pharmaceutical & its intermediates, Peptide, Nutritional supplements,food additive, Plant extracts,and in distributing the products of our own company and affiliated enterprises.
          We have set up R&D center, quality inspection center and manufacturing site in Wuhan, Jiangsu and others places.

    Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. Meanwhile, we possess of complete Q.A. and Q.C. system, supply chemical products with good quality and custom-tailored products according to our clients' requirement.
           We have professional sales team, focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market , our products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc.
         With our constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.
  • Inquiry History
    20 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    N-Acetyl-L-cysteine NAC CAS 616-91-1 with Factory Price

    25 KG Nov 2, 2023
    Singapore

    2-ACETAMIDO-3-MERCAPTOPROPIONIC ACID

    4000 KG Sep 18, 2024
    Philippines

    NAC

    150 KG Aug 31, 2026
    Pakistan

    N-ACETYL-L-CYSTEINE

    1 KG Jan 15, 2026
    Spain

    N-Acetyl-L-cysteine NAC

    1 KG Aug 21, 2026
    Turkey

    N-Acetyl-cysteine

    300 MT Apr 14, 2026
    Romania

    N-acetyl cysteine

    1 KG Mar 25, 2026
    Switzerland

    N-Acetyl-L-Cysteine

    250 KG Jul 18, 2025
    Malaysia

    N-Acetyl-cysteine

    2 MT May 11, 2025
    Brazil

    N-Acetyl-L-Cysteine

    1000 KG Mar 29, 2026
    Brazil

    N-Acetylcysteine (NAC)

    2000 MT Sep 16, 2025
    Pakistan

    ACETYLCYSTEINE

    50 KG Mar 25, 2025
    Netherlands

    N-Acetyl-L-Cysteine

    25 KG Jan 26, 2025
    Australia

    N-Acetyl-L-Cysteine

    5 KG Sep 13, 2024
    United States

    N-Acetyl-L-Cysteine

    750000 KG Mar 4, 2025
    Poland

    N-acetylcysteine

    200 KG Nov 16, 2023
    United States

    N-acetyl cysteine

    100 KG Nov 2, 2023
    Australia

    N-Acetyl-L-Cysteine 99.9% HAIDE Biotech

    10 KG Oct 4, 2023
    Netherlands

    N-Acetyl-L-Cysteine NAC powder CAS 616-91-1 acetylcysteine

    10 KG Mar 16, 2026
    Bulgaria

    Myo-Inositol

    25 KG Feb 5, 2024
    Post an enquiry for this product
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