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High Purity 99% Nootropics Powder Galanthamine Hydrobromide CAS 1953-04-4

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CAS No.:

1953-04-4

Grade:

Pharmaceutical Grade

Content:

Brand:

Packaging:

Foil Bag, Box, Drum

Price valid (until):

2022-12-31

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Xian ZB Biotech Co.,Ltd

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Herb Extracts,Cosmetic raw materails,API

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Product Description
Seller Information
Inquiry History

Description

^{Galantamine Hydrobromide
Galantamine Hydrobromide CAS: 1953-04-4
Galantamine Hydrobromide MF: C17H22BrNO3
Galantamine Hydrobromide MW: 368.27
Galantamine Hydrobromide EINECS: 217-780-5
Product Categories: Alkaloids;Alkaloids (Others);Biochemistry;Functional Products;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Acetylcholine receptor;API;Chiral Reagents;Reminyl;Other APIs;Pharmaceutical intermediates
MP 256 °C
Storage temp. −20°C
Chemical Properties White to Off-White Powder
Usage A selective acetylcholinesterase inhibitor. A therapeutic agent for the treatment and prevention of Alzheimer's disease and other diseases resulting from reduced neuronal metabolism.
Usage Alzheimer treatment;Cholinesterase inhibitor
Usage anticholinesterase, analgesic, antiAlzheimer

Galantamine hydrobromide is the hydrobromide salt of galantamine and is a cholinesterase inhibitor can be extracted from Amaryllidaceae Lycoris plant. The III-phase clinical trials in the United Kingdom in 1998 have showed that this drug had dual mechanism of action of both inhibiting acetylcholinesterase and regulating nicotinic receptors.

Therefore, galantamine can improve the cognitive abilities of Alzheimer's patients and has been already applied as the drug of the treatment of mild to severe Alzheimer's disease (AD) drugs and has entered into market in EC countries. "Chinese Pharmacopoeia" has included the both the raw material and injection of galantamine hydrobromide.}

^{Specification:}

^Items	^{Specification}
^Appearance	^{Brown to Brown yellow powder(Relate to Purity)}
^Oder	^{Characteristic}
^Taste	^{Characteristic}
^{Paiticle size}	^{Pass 80 mesh}
^{Loss on drying}	^≤5%
^{Heavy metals}	^<10ppm
^As	^<1ppm
^Pb	^<3ppm
^Assay	^Result
^Evodiamine	^≥10%
^{Total Plate Count}	^{<10000cfu/g or <1000cfu/g(Irradiation)}
^{Yeast & Mold}	^{<300cfu/g or 100cfu/g(Irradiation)}
^E.Coli	^Negative
^Salmonella	^Negative

Certificates

Basic Info

Product Name:

Galantamine hydrobromide

Other Name:

6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol,4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-,hydrobromide (1:1),(4aS,6R,8aS)-;Galanthamine,hydrobromide;6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol,4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-,hydrobromide,(4aS,6R,8aS)-;Galantamine hydrobromide;Nivalin;Nivaline;Galanthamine hydrogen bromide;Nivaline (pharmaceutical);(-)-Galanthamine hydrobromide;Reminyl;Jilkon hydrobromide;Lycoremine hydrobromide;(-)-Galantamine hydrobromide;Razadyne;Tamilin

CAS No.:

1953-04-4

Molecular Formula:

C17H21NO3.BrH

InChIKeys:

InChIKey=QORVDGQLPPAFRS-XPSHAMGMSA-N

Molecular Weight:

368.27

Exact Mass:

367.078

EC Number:

217-780-5

UNII:

MJ4PTD2VVW

DSSTox ID:

DTXSID4052768

NCI Thesaurus Code:

C47546

Categories:

Nervous System Drugs

Characteristics

PSA:

41.9

XLogP3:

2.74630

Appearance:

White to Off-White Powder

Melting Point:

255-256 °C @ Solvent: Ethanol, 85%

Refractive Index:

-95 ° (C=1.4, H2O)

Water Solubility:

soluble in water or DMSO;Fairly soluble in hot water; freely soluble in alcohol, acetone, chloroform. Less sol in benzene, ether.

Storage Conditions:

−20°C

Vapor Pressure:

0mmHg at 25°C

Specific rotation:

D20 -93.1° (c = 0.1015 in 15 ml H2O)

Collision Cross Section:

166.7 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

See More Galantamine hydrobromide Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 3, Oral

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H301 Toxic if swallowed
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product.
Response	P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P330 Rinse mouth.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Galantamine hydrobromide Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Herb Extracts,Cosmetic raw materails,API

Location:
1403,Jinye B Block

Payment Terms:
TT against copy of documents

Average lead Time:
8

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
11-50

Year of Establishment:
2015

Xian ZB Biotech Co.,Ltd is a leading Manufactory supplier of Arbutin, Nicotinamide, Flucytosine based in Xi'an, Shaanxi, China. With a commitment to quality and customer satisfaction, Xian ZB Biotech Co.,Ltd has become a trusted name in the industry. Our product line includes a range of high-quality Arbutin, Nicotinamide, Flucytosine, which are available at competitive prices. Xian ZB Biotech Co.,Ltd has established itself as a reliable supplier of chemical products on the echemi.com.

Inquiry History

4 Inquiries

Country	Product	Purchase Quantity	Date Posted
Colombia	Galantamine Hydrobromide 99% white powder 1953-04-4 Lingding044	1 KG	May 30, 2023
Saudi Arabia	Galantamine Hydrobromide	1 20' Fcl	Apr 28, 2026
United States	Galanthamine hydrobromide	10 KG	Oct 18, 2023
South Korea	Donephezil	100 MG	Jul 2, 2024

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