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Skin Whiten Vitamin B3 Capsule/Nicotinamide Powder CAS 98-92-0 Nicotinamide

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CAS No.:

98-92-0

Grade:

Pharmaceutical Grade;Cosmetic Grade

Content:

Brand:

Packaging:

Boil Bag

Sample Available:

Yes

Price valid (until):

2022-12-31

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Xian ZB Biotech Co.,Ltd

Company Type:

Manufactory

Location:

China

Payment Terms:

TT against copy of documents

Average Lead Time:

8 days

Qualification:

Main Products:

Herb Extracts,Cosmetic raw materails,API

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Description

Skin Whiten Vitamin B3 Capsule/Nicotinamide Powder CAS 98-92-0 Nicotinamide

1.Quick details of Nicotinamide/Vitamin B3

Product Name:	Nicotinamide
Synonyms:	3-PYRIDINECARBOXAMIDE;3-PYRIDINE CARBOXYLIC ACID AMIDE;3-PYRIDINECARBOXYLIC AMIDE;TIMTEC-BB SBB004283;NICETHAMIDUM;NIACINAMIDE;NICOTINIC ACID AMIDE;NICOTINAMIDE
CAS:	98-92-0
MF:	C6H6N2O
MW:	122.12
EINECS:	202-713-4
Chemical Properties	White crystalline powder
Uses	Vitamin B3; enzyme cofactor; anti-pellagra

2.Production Description of Nicotinamide/Vitamin B3

Nicotinamide is a water-soluble vitamin, The product is white crystalline powder, odorless or nearly odorless, bitter in taste, freely soluble in water or ethanol, dissolvable in glycerin.

Nicotinamide is easy to absorb oral, and can be widely distributed in the body, the excess metabolites or prototype quickly expel from urine.
Nicotinamide is part of coenzyme I and coenzyme II, plays the role of hydrogen delivery in biological oxidation respiratory chain, can promote biological oxidation processes and tissue metabolism, maintain normal tissue (especially the skin, digestive tract and nervous system) integrity has an important role.

In addition, nicotinamide has prevention and treatment of heart block, sinus node function and anti-fast experimental arrhythmias, nicotinamide can significantly improve the heart rate and atrioventricular block caused by verapamil.

3.COA of Nicotinamide/Vitamin B3

Item	Standard	Test method	Results
Assay (%)	98.5-101.5	HPLC	99.7
Identification A	Conform	IR	Conform
Identification B (Ratio:A245/A262)	0.63-0.67	UV	0.67
Melting range,°C	128-131	Melting point apparatus	129.3-129.9
Loss on drying ,%	≤0.5	Silicagel drier	0.04
Residue on ignition,%	≤0.1	High temperature ignition	0.03
Heavy metals, %	≤0.003	Colorimetry	<0.003
Readily carbonizable substances	Conform	Colorimetry	Conform

Don't hesitate to contact us for latest COA and Test Report of Nicotinamide/Vitamin B3

4.Fuction of Nicotinamide/Vitamin B3

1. Vitamin B3 Niacin can prevent and control glossitis.

2. Vitamin B3 Niacin can help treat atrioventricular block.

3. Vitamin B3 Niacin can prevent and control sinus syndrome.

4. Vitamin B3 Niacin prevents and controls parallel, rough skin inflammation.

5.Application of Nicotinamide/Vitamin B3

1.Nicotinamide can prevent pathological changes of skin and diseases of alimentary canal, such as dermatitis, black tongue, vomiting and diarrhea etc.

2.Nicotinamide by participating in material and energy metabolism,nicotinamide can promote the body growth.

3.Nicotinamide by combining with other medicines, Nicotinamide can cure catarrh and ulcer.

4.Nicotinamide by improving the ability of blood supply with strong expansion function of blood vessel,Nicotinamide is highly effective in curing such diseases as dermatosis, hypercholesterolemia disease and coronary heart disease.

ECHEMI Editorial Reference

It is white needle crystal or crystalline powder, no smell or odor slightly, slightly bitter taste. The relative density is 1.4, melting point is 131-132 ℃.1 g of the above the product is soluble in 1 ml of water, 1.5 ml ethanol or 10 ml glycerin, insoluble in ether. The pH of 10% aqueous solution is 6.5-7.5. in dry air to light and heat stability, in alkaline or acidic solution, heating generation to nicotinic acid. Rats by oral LD502.5-3.5g/kg ADI value does not make special provisions (ECC,
Nicotinamide is a white powder. (NTP, 1992)|DryPowder; OtherSolid|Solid|WHITE CRYSTALLINE POWDER.
Nicotinamide is a white powder. (NTP, 1992)|Nicotinamide is a pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group. It has a role as an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor, a metabolite, a cofactor, an antioxidant, a neuroprotective agent, an EC 3.5.1.98 (histone deacetylase) inhibitor, an anti-inflammatory agent, a Sir2 inhibitor, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a mouse metabolite, a human urinary metabolite and a geroprotector. It is a vitamin B3, a pyridinecarboxamide and a pyridine alkaloid. It derives from a nicotinic acid.|Mediatric is a DEA Schedule III controlled substance. Substances in the DEA Schedule III have a potential for abuse less than substances in Schedules I or II and abuse may lead to moderate or low physical dependence or high psychological dependence.|An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.|Vitamin B refers to several water soluble vitamins often found together in foods, all of which are necessary for normal growth and metabolism, but none of which are synthesized in adequate amounts by humans. The common forms of vitamin B include vitamin B1 (thiamine), B2 (riboflavin), B3 (niacin), B6 (pyridoxine) and B12 (cyanocobalamin). Except for niacin (when given in high doses), there is no evidence that the other B vitamins, in physiologic or even super-physiologic high doses cause liver injury or jaundice. The major forms of vitamin B and selected other water soluble vitamins (biotin, pantothenic acid, choline) are discussed briefly in this record.|Niacinamide is the active form of vitamin B3 and a component of the coenzyme nicotinamide adenine dinucleotide (NAD). Niacinamide acts as a chemo- and radio-sensitizing agent by enhancing tumor blood flow, thereby reducing tumor hypoxia. This agent also inhibits poly(ADP-ribose) polymerases, enzymes involved in the rejoining of DNA strand breaks induced by radiation or chemotherapy.|An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.

Certificates

Basic Info

Product Name:

Nicotinamide

Other Name:

3-Pyridinecarboxamide;Nicotinamide;Aminicotin;Benicot;Delonin Amide;Dipegyl;NAM;Niacinamide;Nicamindon;Nicofort;Nicotilamide;Nicotine acid amide;Nicotinic acid amide;Nicotinic amide;Nicotylamide;Niocinamide;Niozymin;Pelonin amide;3-Pyridinecarboxylic acid amide;Vi-Nicotyl;Vitamin B3 (niacinamide);Vitamin B;Nicosan 2;3-Carbamoylpyridine;Pelmine;β-Pyridinecarboxamide;Nicobion;Nicosylamide;Nicovit;Niavit PP;Nicovitina;Nicamina;Nicasir;3-(Aminocarbonyl)pyridine;m-(Aminocarbonyl)pyridine;3-Amidopyridine;Papulex;Nictoamide;Pelmin;NSC 13128;NSC 27452;Vitamin B3 (nicotinamide);123574-63-0;37321-14-5;78731-47-2

CAS No.:

98-92-0

Molecular Formula:

C6H6N2O

InChIKeys:

InChIKey=DFPAKSUCGFBDDF-UHFFFAOYSA-N

Molecular Weight:

122.12500

Exact Mass:

122.12

EC Number:

202-713-4

UNII:

25X51I8RD4

DEA Code Number:

1405

ICSC Number:

1703

NSC Number:

759115|27452|13128

DSSTox ID:

DTXSID2020929

NCI Thesaurus Code:

C2327

Color/Form:

White, powder, needles from benzene|Colorless crystalline solid|White, crystalline powder|Colorless needles

ATC Code:

A11HA01|A - Alimentary tract and metabolism

HScode:

2933399090

Categories:

Blood Glucose Regulators

Characteristics

PSA:

55.98000

XLogP3:

0.88080

Appearance:

Nicotinamide is a white powder. (NTP, 1992)

Density:

1.400 g/cm³ @ Temp: 25 °C

Melting Point:

130 °C

Boiling Point:

157 °C @ Press: 5 x 10^-4 Torr

Flash Point:

182°C

Refractive Index:

1.4660 (estimate)

Water Solubility:

1000 g/L (20 ºC)

Storage Conditions:

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Vapor Pressure:

Vapour pressure, kPa at 35°C: 3.1

Vapor Density:

Relative vapour density (air = 1): 4.2

Toxicity:

LD50 s.c. in rats: 1.68 g/kg (Brazda, Coulson)

Odor:

Odorless

Taste:

Bitter taste

PH:

10% "wt in vol" solution in water is neutral to litmus

PKA:

3.35(at 20 °C)

Henrys Law Constant:

Henry's Law constant = 2.90X10-12 atm-cu m/mol at 25 °C (est)

Dissociation Constants:

3.35 (at 20 °C)|pKa = 3.35 (conjugate acid)|kb1 = 2.24X10-11; kb2 = 3.16X10-14

Collision Cross Section:

125.3 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|129.32 Å² [M+H]+ [CCS Type: DT, Method: stepped-field]|137.3 Å² [M+Na]+ [CCS Type: DT, Method: stepped-field]|118 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine]|125.3 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|121.7 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]|125.2 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated]|126.7 Å² [M+H]+

Experimental Properties:

Readily hydrolyzed to free acid by heating in acid or alkaline solution|Forms crystalline salts with acids|Hydroxyl radical reaction rate constant = 2.34X10-12 cu cm/molec sec at 25 °C (est)

Air and Water Reactions:

Water soluble.

Reactive Group:

Amides and Imides

Reactivity Profile:

An amine and amide. Acts as a weak base in solution. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

Autoignition Temperature:

480 °C

Physical Dangers:

Dust explosion possible if in powder or granular form, mixed with air.

See More Nicotinamide Properties 

Hazard Identification

Classification of the substance or mixture

Eye irritation, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H319 Causes serious eye irritation
Prevention	P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Prevent deposition of dust. Closed system, dust explosion-proof electrical equipment and lighting. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Separated from oxidants.

See More Nicotinamide Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Herb Extracts,Cosmetic raw materails,API

Location:
1403,Jinye B Block

Payment Terms:
TT against copy of documents

Average lead Time:
8 days

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
11-50

Year of Establishment:
2015

Xian ZB Biotech Co.,Ltd is a leading Manufactory supplier of Arbutin, Nicotinamide, Flucytosine based in Xi'an, Shaanxi, China. With a commitment to quality and customer satisfaction, Xian ZB Biotech Co.,Ltd has become a trusted name in the industry. Our product line includes a range of high-quality Arbutin, Nicotinamide, Flucytosine, which are available at competitive prices. Xian ZB Biotech Co.,Ltd has established itself as a reliable supplier of chemical products on the echemi.com.

Inquiry History

107 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	Nicotinamide	45.00 KG	Jun 13, 2025
India	Nicotinamide	25.00 KG	Jun 12, 2025
India	Nicotinamide	50.00 KG	Jun 11, 2025
India	Nicotinamide	50.00 KG	Jun 13, 2025
United States	Niacinamide	1 KG	Feb 5, 2024
India	Nicotinamide	25.00 KG	Jun 11, 2025
Egypt	Niacinamide	1.00 KG	Aug 28, 2026
Russia	Niacinamide	1 KG	Dec 2, 2024
India	Niacinamide	100.00 KG	Aug 3, 2026
Pakistan	Niacinamide	5.00 KG	Sep 14, 2026
Algeria	Niacinamide	1.00 KG	Sep 17, 2026
Denmark	Niacinamide	5.00 MT	Sep 9, 2026
India	Niacinamide	200.00 KG	Sep 2, 2026
India	Niacinamide	1.00 KG	Aug 31, 2026
India	Niacinamide	1.00 KG	Aug 22, 2026
Nigeria	Niacinamide	100.00 KG	Aug 20, 2026
Uganda	Niacinamide	500 G	Aug 13, 2026
Pakistan	Niacinamide	10.00 MT	Jul 10, 2026
India	Nicotinamide	1 KG	Jul 1, 2026
South Korea	Niacinamide	150 KG	Jun 29, 2026

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Product Description

Seller Information

Inquiry History

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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