Local Anesthetics Algesia Celecoxib Powder CAS: 169590-42-5 Celecoxib
GMP HALAL KOSHER ISO FDA 5 Inquiries
169590-42-5
Pharmaceutical Grade
0%
Boil Bag
2022-12-31
Herb Extracts,Cosmetic raw materails,API
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Product Description
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Seller Information
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Inquiry History
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Description
Celecoxib is a selective Cox-2(cyclooxygenase-2) inhibitor (IC50 of 40 nM). Celecoxib shows low sensitivity against Cox-1 (IC50 of 15 μM). Celecoxib shows an anti-proliferative effect on nasopharyngeal carcinoma (NPC) cell lines including HNE1 (IC50of 32.86 μM) and CNE1-LMP1 (IC50 of 61.31 μM).Celecoxib
Celecoxib is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID). It is used to treat the pain and inflammation of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute pain in adults, painful menstruation, and juvenile rheumatoid arthritis in people .
Product name
Celecoxib
Origin
China
CAS
169590-42-5
Grade
Medical grade
Test
Specifications
Appearance
White to off-white crystalline powder.
Freely soluble in methanol,ethanol,acetone and dimethyl sulfoxide, practically insoluble in water.
Melting Point
160.0~164.0ºC
Identification
A.The infrared absorption spectrum should meet with the reference spectrum
B.The retention time of sample major peak should meet with the retention time of reference substance major peak.
Water
≤0.5%
Residue On Ignition
≤0.2%
Heavy Metal
≤20ppm
Fluorine
14.2%~16.4%
Related substances
Any individual impurity≤0.5%
Total impurities≤1.0%
Residual Solvent
complies
Assay(on dried basis)
98.0% ~102.0%
Conclusion
Conform with specification
Storage
Store in sealed containers at cool & dry place.
Protect from light, moisture and pest infestation.
Shelf life
2 years when properly stored
Celecoxib is used for osteoarthritis, rheumatoid arthritis, acute pain, musculoskeletal pain, painful menstruation, ankylosing spondylitis, and to reduce the number of colon and rectal polyps in people with familial adenomatous polyposis.It may also be used in children with juvenile rheumatoid arthritis who are older than two years of age and weigh more than 10 kg (22 lb).
For postoperative pain, it is more or less equal to ibuprofen. For pain relief, it is similar to paracetamol (acetaminophen).And in osteoarthritis, acetaminophen is the first line treatment.In knee and hip osteoarthritis, acetaminophen may be ineffective.
CertificatesBasic Info-
Product Name:
Celecoxib
Other Name:Benzenesulfonamide,4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-;4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide;Celecoxib;SC 58635;YM 177;Celebrex;Celocoxib;Celebra;Celecox;Xilebao;Medicoxib;Eurocox;Onsenal;4-[5-(p-Tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide;184007-95-2;194044-54-7
CAS No.:169590-42-5
Molecular Formula:C17H14F3N3O2S
InChIKeys:InChIKey=RZEKVGVHFLEQIL-UHFFFAOYSA-N
Molecular Weight:381.37
Exact Mass:381.37
EC Number:200-001-8
UNII:JCX84Q7J1L
NSC Number:758624|719627
DSSTox ID:DTXSID0022777
NCI Thesaurus Code:C1728
Color/Form:Pale yellow solid
ATC Code:L01XX33|M01AH01|L - Antineoplastic and immunomodulating agents|M - Musculo-skeletal system
HScode:2935009090
Categories:
Characteristics-
PSA:
86.4
XLogP3:3.4
Appearance:white to off-white
Density:1.4±0.1 g/cm3
Melting Point:157-159 °C
Boiling Point:529.0±60.0
Flash Point:273.7±32.9 °C
Refractive Index:1.606
Water Solubility:DMSO: >20mg/mL
Storage Conditions:Store at RT
Vapor Pressure:1.2X10-9 mm Hg at 25 deg C /Estimated/
PKA:11.1None
Henrys Law Constant:Henry's Law constant = 7.75X10-13 atm-cu m/mol at 25 °C (est)
Dissociation Constants:11.1|pKa = 11.1 (sulfonamide moiety)
Collision Cross Section:186.4 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)]|186.1 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Experimental Properties:Hydroxyl radical reaction rate constant = 1.45X10-11 cu cm/molec-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
Reproductive toxicity, Category 1B
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H360 May damage fertility or the unborn child
Precautionary statement(s) Prevention P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Herb Extracts,Cosmetic raw materails,API
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Location:
1403,Jinye B Block
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Payment Terms:
TT against copy of documents
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Average lead Time:
8
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2015
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Inquiry History5 Inquiries
Country Product Purchase Quantity Date Posted 
Pakistan
Celecoxib
100 KG Oct 27, 2025
Pakistan
Celecoxib Usp
200 KG May 13, 2025
Pakistan
Celecoxib
50 KG Sep 24, 2025 
India
Celecoxib
100 G Jan 18, 2024 
Finland
Celecoxib
500 G Jul 3, 2023 Post an enquiry for this product