High Purity 99% Vortioxetine Hydrobromide for Anti-Depressant
HALAL ISO FDA
960203-27-4
0%
ZB
Foil Bag, Box, Drum
2022-12-31
Herb Extracts,Cosmetic raw materails,API
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Product Description
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Seller Information
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Description

Prodcut name
Vortioxetine hydrobromide
Synonyms
1-[2-[(2,4-Dimethylphenyl)thio]phenyl]pipe hydrobromide
MOQ
1G
CAS No.
960203-27-4
Appearance
white to off white crystalline powder
Molecular Formula
C 18 H 22 N 2 S . HBr
Molecular Weight
379.36
Assay
98.0~102.0%
Application
Pharma grade or research purpose
Packing
As per your request
Storage
Preserve in tight,light-resistant containers in a cool place
Remarks
Enterprise standard
Custom synthesis
Available
Supply Ability
50kg/month
Valticetine hydrobromide is considered to be a novel multi-model antidepressant drug. In vitro studies have shown that it can antagonize 5-HT3, 5-HT7 and 5-HT1D receptors, activate 5-HT1A receptors, and partially activate 5- HT1B receptors and inhibit 5-HT transport.
For the treatment of mild to moderate or severe depression Neurogenic and Reactive Depression Physiotherapy, especially gastrointestinal distress Depression Anxiety Depression in patients with alcohol dependence during withdrawal.
ECHEMI Editorial ReferenceVortioxetine hydrobromide is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with Ki values of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively.
Vortioxetine hydrobromide is a hydrobromide obtained by combining vortioxetine with one molar equivalent of hydrobromic acid. Used for treatment of major depressive disorder. It has a role as an antidepressant, an anxiolytic drug, a serotonergic antagonist and a serotonergic agonist. It contains a vortioxetine(1+).|Vortioxetine Hydrobromide is a hydrobromide salt form of vortioxetine, a serotonin (5-HT) modulator and stimulator (SMS), with antidepressant activity. Vortioxetine inhibits the reuptake of serotonin and norepinephrine from the synaptic cleft and acts variably as a serotonin receptor agonist (5-HT1A), partial agonist (5-HT1B) or antagonist (5-HT3, 5-HT1D and 5-HT7). It is not clear how this agent's purported multimodal mechanism of action contributes to its antidepressant effect; however, it is presumed to increase the synaptic availability of serotonin and norepinephrine.|A piperazine derivative that acts as a serotonin reuptake inhibitor, as a 5-HT3 receptor antagonist, and 5-HT1A receptor agonist. It is used for the treatment of anxiety and depression.CertificatesBasic Info-
Product Name:
Vortioxetine hydrobromide
Other Name:Piperazine,1-[2-[(2,4-dimethylphenyl)thio]phenyl]-,hydrobromide (1:1);Lu AA 21004 hydrobromide;Vortioxetine hydrobromide;1-[2-[(2,4-Dimethylphenyl)thio]phenyl]piperazine hydrobromide;2361026-23-3
CAS No.:960203-27-4
Molecular Formula:C18H22N2S.BrH
InChIKeys:InChIKey=VNGRUFUIHGGOOM-UHFFFAOYSA-N
Molecular Weight:379.35762
Exact Mass:378.076538
UNII:TKS641KOAY
NCI Thesaurus Code:C125653
ATC Code:N06AX26
HScode:29339900
Categories:
Characteristics-
PSA:
40.6
XLogP3:5.21610
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
Skin sensitization, Category 1
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
H317 May cause an allergic skin reaction
H410 Very toxic to aquatic life with long lasting effects
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P273 Avoid release to the environment.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P333+P317 If skin irritation or rash occurs: Get medical help.
P321 Specific treatment (see ... on this label).
P362+P364 Take off contaminated clothing and wash it before reuse.
P391 Collect spillage.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Herb Extracts,Cosmetic raw materails,API
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Location:
1403,Jinye B Block
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Payment Terms:
TT against copy of documents
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Average lead Time:
8
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2015
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Country Product Purchase Quantity Date Posted Post an enquiry for this product