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PILOCARPINE

Name: PILOCARPINE
Brand: Pharma;Conutrix
SKU: pr22061011273
Price: 0.2 USD
Availability: InStock

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CAS No.:

92-13-7

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Brand:

Pharma;Conutrix

Packaging:

25kg/Cardboard Drum

Sample Available:

Yes

Price valid (until):

2022-12-31

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Shaanxi Dideu Medichem Co. Ltd

Company Type:

Manufactory

Location:

China

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

7 days

Qualification:

Main Products:

Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst

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Product Description
Seller Information

Description

Our Reference Specification, for more details, pls contact us for COA, MSDS and certification:

Email & Skype: Service@dideu.com Telephone:+86-29-89586680
Mobile:+86-15129568250; Whatsapp&Wechat: +8615129568250

Item	Standard	Test Results
Identification	A.H-NMR:Comply with the structure	Complies
	B.LC-MS:Comply with the structure	Complies
	C.The IR spectrum of sample should be identical with that of reference standard.	Complies
	D.HPLC-ESI-MS	Complies
	The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.	Complies
Loss on drying	≤2.0%	0.19%
Heavy metals	≤10 ppm	<10ppm
Water	≤1.0%	0.10%
Sulphated ash	≤0.5% determined on 1.0 g.	0.01%
Residue on ignition	≤0.1%	0.03%
Related Substances	Unspecified impurities: for each impurity ≤0.10%	<0.10%
Related Substances	Total Impurity ≤0.5%	0.18%
Purity	≥99.0%	99.70%
Assay	99.0%~101.0% (anhydrous substance).	99.80%
Storage	Preserve in well-closed, light-resistant and airtight containers.	Complies

Our normal packaging is 25kgs/Drum and 200kgs/Drum.
The packaging can be customized. the shipping term can be by sea, by air, and sample or small quantity can be shipped by DHL, FEDEX, EMS and TNT.

a) Free sample can be supplied.
b) Guide our clients by professional knowledge and teach them how to use our product after sales.
c) Accept SGS, BV any other third-party inspection before loading.
d) High quality best price Guaranteed.2,6-二氯烟酸乙酯

Why do you choose Dideu Industries as your partner?
A) High quality can be guaranteed. Dideu Industries since 1975 are reputed chemical manufacturer and are Certified by ISO 9001;2015 and have GMP certification.Free sample can be arranged before shipment and SGS,BV and other third party inspection company are accepted before loading.For regular customers, we accept L/C 180 Days, D/P,D/A payment term. If there is any quality problem after goods arrive. Dideu Industries will do fully payment refund.
B) Best price can be guaranteed. As Dideu Industries are integrated pharmaceuticals and chemicals producer, the production cost can be controlled and price will be definitely more competitive than China trading companies.
C) Professional enginners from Dideu Industries will give professional usage guide and services after sales.
D) Dideu Industries work 7×24 hours and your request will be processed by our professional staff in different shift period.

ECHEMI Editorial Reference

Colorless crystalline solid or an oil; melts at34°C (93.2°F); dissolves in water, alcohol,and chloroform; slightly soluble in ether andbenzene.
Solid
(+)-pilocarpine is the (+)-enantiomer of pilocarpine. It has a role as an antiglaucoma drug. It is an enantiomer of a (-)-pilocarpine.|A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.|Pilocarpine is a Cholinergic Receptor Agonist. The mechanism of action of pilocarpine is as a Cholinergic Agonist, and Cholinergic Muscarinic Agonist.|Pilocarpine is an orally available cholinergic agonist that is used to treat symptoms of dry mouth in patients with keratoconjunctivitis sicca (Sjögren syndrome) or with xerostomia (dry mouth) due to local irradiation. Pilocarpine has not been linked to serum enzyme elevations during therapy or to instances of clinically apparent liver injury.|Pilocarpine is a natural alkaloid extracted from plants of the genus Pilocarpus with cholinergic agonist activity. As a cholinergic parasympathomimetic agent, pilocarpine predominantly binds to muscarinic receptors, thereby inducing exocrine gland secretion and stimulating smooth muscle in the bronchi, urinary tract, biliary tract, and intestinal tract. When applied topically to eyes, this agent stimulates the sphincter pupillae to contract, resulting in miosis; stimulates the ciliary muscle to contract, resulting in spasm of accommodation; and may cause a transitory rise in intraocular pressure followed by a more persistent fall due to opening of the trabecular meshwork and an increase in the outflow of aqueous humor.

Basic Info

Product Name:

Pilocarpine

Other Name:

2(3H)-Furanone,3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-,(3S,4R)-;Pilocarpine;2(3H)-Furanone,3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-,(3S-cis)-;(3S,4R)-3-Ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone;Pilocarpol;Pilocarpine,(+)-;(+)-Pilocarpine;Pilokarpin;Syncarpine;Ocusert P 20;Ocusert Pilo 40;Ocucarpine;Ocusert Pilo;Spersacarpine;91484-73-0

CAS No.:

92-13-7

Molecular Formula:

C11H16N2O2

InChIKeys:

InChIKey=QCHFTSOMWOSFHM-WPRPVWTQSA-N

Molecular Weight:

208.26

Exact Mass:

208.26

EC Number:

202-128-4

UNII:

01MI4Q9DI3

DSSTox ID:

DTXSID1021162

NCI Thesaurus Code:

C62068

Color/Form:

OIL OR CRYSTALS|NEEDLES

ATC Code:

S01EB01|N - Nervous system|S - Sensory organs

HScode:

2939800000

Categories:

Nervous System Drugs

Characteristics

PSA:

44.1

XLogP3:

1.1

Appearance:

Solid

Density:

1.2±0.1 g/cm3

Melting Point:

34 °C

Boiling Point:

260 °C

Flash Point:

215.0±21.2 °C

Refractive Index:

1.585

Water Solubility:

2.07e+00 g/L

Storage Conditions:

KEEP WELL CLOSED & PROTECTED FROM LIGHT. /HCL/

Specific rotation:

D18 +106° (c = 2)

PKA:

6.78None

Dissociation Constants:

6.78|PK1= 7.15; PK2= 12.57 @ 20 °C

Experimental Properties:

WHITE CRYSTALS; SLIGHTLY BITTER; MP: 195-198 °C; ALSO GIVEN AS 204-205 °C; 1 G DISSOLVES IN 0.3 ML WATER, 3 ML ALCOHOL, 366 ML CHLOROFORM; INSOL IN ETHER; /HCL/|ODORLESS, FAINTLY BITTER CRYSTALS; SOLN ACID TO LITMUS; PKA1= 6.8, PKA2= 1.3 /HCL/|MP: 173.5-174.0 °C DECOMP; SPECIFIC OPTICAL ROTATION: +77 DEG TO +83 °FOR D (SODIUM) LINE (10%); 1 G DISSOLVES IN 4 ML WATER, 75 ML ALCOHOL; INSOL IN CHLOROFORM, ETHER /NITRATE/|SOL ARE ACID TO LITMUS /NITRATE/|WHITE POWDER OR CRYSTALS FROM ALC /NITRITE/

See More Pilocarpine Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 2, Oral

Acute toxicity - Category 2, Inhalation

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H300 Fatal if swallowed H330 Fatal if inhaled
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P260 Do not breathe dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P284 [In case of inadequate ventilation] wear respiratory protection.
Response	P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P330 Rinse mouth. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P316 Get emergency medical help immediately. P320 Specific treatment is urgent (see ... on this label).
Storage	P405 Store locked up. P403+P233 Store in a well-ventilated place. Keep container tightly closed.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Keep well closed & protected from light. hcl

See More Pilocarpine Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst

Location:
https://www.dideu.com/en/

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
7 days

Total Annual Revenue:
Above $100 million

Total Employees:
Above 1000

Year of Establishment:
2016

Company Certificates
- ISO Certificate
- REACH
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PILOCARPINE

Product Description

Seller Information

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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