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Tolazamide 99% white powder GB0234 Greenbo

Name: Tolazamide 99% white powder GB0234 Greenbo
Brand: Greenbo
SKU: pr2206102487
Price: 1 USD
Availability: InStock

Unit Price: Get Latest Price 

CAS No.:

1156-19-0

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Brand:

Greenbo

Packaging:

25kg Drum

Sample Available:

Yes

Price valid (until):

2022-07-31

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Greenbo Biochem

Company Type:

Manufactory

Location:

China

Payment Terms:

TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

15 days

Qualification:

Main Products:

Active Pharm Ingredients,Chemical Catalyst,Pharmaceutical Intermediates,Flavors and Fragrances,Agrochemicals,Chemical Pesticides

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Product Details
Seller Information

Description

High quality USP/EP/BP 20 GMP DMF FDA Tolazamide CAS NO 1156-19-0 producer

Our Reference Specification, for more details, pls contact us for COA,MSDS and certification:

Skype: Avgem_alic Mobile:+86-18192575886; Whatsapp&Wechat: +8618192575886 Mail: mailto:Market@greenbo-biochem.com

Item	Standard	Test Results
Identification	A.H-NMR:Comply with the structure	Complies
	B.LC-MS:Comply with the structure	Complies
	C.The IR spectrum of sample should be identical with that of reference standard.	Complies
	D.HPLC-ESI-MSThe retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.	Complies
Crystallinity	meets the requirements.	Complies
Loss on drying	≤2.0%	0.19%
Heavy metals	≤10 ppm	<10ppm
Water	≤1.0%	0.1%
Sulphated ash	≤0.5% determined on 1.0 g.	0.009%
Residue on ignition	≤0.1%	0.03%
Related Substances	Unspecified impurities: for each impurity ≤0.10%	<0.10%
Related Substances	Total Impurity ≤0.5%	0.18%
Purity	≥99.0%	99.7%
Assay	99.0%~101.0% (anhydrous substance).	99.8%
Microbiological Analysis	Total plate count ≤1000cfu/g	Complies
	Yeast & Moulds ≤100cfu/g	Complies
	E. Coli. Absent	Negative
	Salmonella Absent	Negative
	S.aureus Absent	Negative
Storage	Preserve in well-closed,light-resistant and airtight containers.	Complies

Our normal packaging is 25kgs/Drum

The packaging can be customized. the shipping term can be by sea, by air, and sample or small quantity can be shipped by DHL, FEDEX, EMS and TNT.

Q1: Is there any possible to use my appointed label or package?

Re: Yes. If needed, we'd like to use label or package according to your requirement.
Q2: Why should you buy from us not from other suppliers?
High-quality products with reasonable price;

Delivering consistent and reliable quality products on time.

Warm Service and Best after-sale service from our professional team.

Q3: Which kind of payment terms do you accept?

A: For small order, you can pay by T/Tor PayPal. bulk order by T/T or L/C to our company account.

Q4: Can you give me a discount price?

Surely, it depends on your Qty.

Q5. What services can we provide or why you choose Greenbo as your reliable partner in China?

1.Greenbo biochem work 7×24 hours and your request and after-sale service will be processed by our professional staff on time

2. Higher quality can be guaranteed. Greenbo biochem are reputed chemical manufacturer and are Certified by ISO 9001;2015. Quality is our life and Quality is the guarantee of long-term cooperation. In addition to advocating mediocre quality control, we will strengthen the principle of good quality control. In the process of delivering to customers, we will focus on the details, confirm the sample standards with customers, and ensure the unity of large goods and sample standards. We will have our own quality inspectors to conduct sampling inspection on large goods. We also welcome customers to entrust third-party sampling inspection. We are committed to solving some problems before loading the goods, so as to reduce unnecessary losses for both buyers and sellers.

3.Best price can be guaranteed. As Greenbo are integrated pharmaceuticals and chemicals producer, the production cost can be controlled and price will be definitely more competitive than China trading companies.

4. Best after-sales service can be supplied. Greenbo biochem have professional team for after-sales service. If you have any complaints for our product and sales. please contact us ASAP by mailto:account@greenbo-biochem.com

Shaanxi Greenbo Biochem Co., Limited

is located in the High-Tech Zone of Xi'an, Shaanxi Province. which is a world-class innovation company and core competencies in the fields of health care and farm chemical. Since 2002 we are the high-tech corporation with GMP and ISO9001:2008 specializing in the production and research of farm chemical and its intermediates, Nutritional supplement and plant extract for pharmaceutical, Food, beverage, Cosmetic industry. With our innovative products, we are contributing to finding solutions to some of the major challenges of our time. The growing and increasingly aging world population requires improved medical care and an adequate supply of food. Greenbo is improving people’s quality of life by preventing, alleviating and treating diseases. And we are helping to provide a reliable supply of high quality green agricultural chemical, high-quality food, feed additive and plant-based raw materials. We develop new molecules for use in innovative products and solutions to improve health. By strict standing with the current GMP and tight QC procedures, with our skilled personal and special equipment, we saved the cost during production, make the manufacture effectiveness and also worked out with innovative pharmaceutical, food, cosmetic products. We also focus on the quality control and technology innovation. Greenbo R& D Center has a dedicated professional team tracking every step in our production. Up to now our center has developed long term cooperation with the professors, experts from Xi'an Jiao Tong University, Zhejiang University, engaging to the research and develop of the latest technology and new products.

At Greenbo, we insist the principle of Top quality, Excellent Service, Outstanding technology innovation, Constantly develop. And our consistent objective is mutually benefit and win-win with customers and developing together, our code of practice for customer service is to make conveniences and benefit for customers; we do concern for customers, and searching solution of difficult problems from market feedbacks, so as to provide better service and tailored technical support, expanding our market and establish reputations. Our sales network covers 29 provinces in china. And internationally, our products were exported to Europe, America, Australia, Russia, Japan, Korea, and southeast Asia. Good commercial integrity and stable customer group make Greenbo to extend our business to the whole world. We sincerely welcome you to join us and create and even brighter future with you together.

ECHEMI Editorial Reference

White SolidChEBI: An N-sulfonylurea that is 1-tosylurea in which a hydrogen attached to the nitrogen at position 3 is replaced by an azepan-1-yl group. A hypoglycemic agent, it is used for the treatment of type 2 diabetes mellitus.Tolazamide is N-[[(hexahydro-1H-azepin-1-yl)amino]carbonyl]-4-methylbenzenesulfonamide; or 1-(hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)urea; or 1-(4-methylphenylsulfonyl)-3-(hexahydro-1H-azepin-1-yl)urea (generic).Tolazamide incorporates a fully saturated azepine
Tolazamide appears as white to off-white crystalline powder. Odorless or with a slight odor. (NTP, 1992)|Solid
Tolazamide appears as white to off-white crystalline powder. Odorless or with a slight odor. (NTP, 1992)|Tolazamide is an N-sulfonylurea that is 1-tosylurea in which a hydrogen attached to the nitrogen at position 3 is replaced by an azepan-1-yl group. A hypoglycemic agent, it is used for the treatment of type 2 diabetes mellitus. It has a role as a hypoglycemic agent and a potassium channel blocker.|A sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide.|Tolazamide is a Sulfonylurea.|Tolazamide is an intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. Tolazamide is converted into five major metabolites that are excreted into the urine. Tolazamide is more potent than tolbutamide and similar in potency to chlorpropamide on a milligram basis. This agent may cause cholestatic jaundice.|A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE.

Basic Info

Product Name:

Tolazamide

Other Name:

Benzenesulfonamide,N-[[(hexahydro-1H-azepin-1-yl)amino]carbonyl]-4-methyl-;Urea,1-(hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)-;N-[[(Hexahydro-1H-azepin-1-yl)amino]carbonyl]-4-methylbenzenesulfonamide;U 17835;1-(Hexahydro-1-azepinyl)-3-p-tolylsulfonylurea;1-(Hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)urea;Tolazamide;Tolinase;N-(p-Toluenesulfonyl)-N′-hexamethyleniminourea;Norglycin;Tolanase;1-(4-Methylphenylsulfonyl)-3-(hexahydro-1H-azepin-1-yl)urea;Diabewas;NSC 70762;1-(Azepan-1-yl)-3-(4-methylphenyl)sulfonylurea

CAS No.:

1156-19-0

Molecular Formula:

C14H21N3O3S

InChIKeys:

InChIKey=OUDSBRTVNLOZBN-UHFFFAOYSA-N

Molecular Weight:

311.4

Exact Mass:

311.40

EC Number:

214-588-3

UNII:

9LT1BRO48Q

NSC Number:

758149|70762

DSSTox ID:

DTXSID3021358

NCI Thesaurus Code:

C29502

Color/Form:

Crystals|WHITE TO OFF-WHITE, CRYSTALLINE POWDER

ATC Code:

A - Alimentary tract and metabolism

HScode:

2935904000

Categories:

Other Chemical Drugs

Characteristics

PSA:

86.9

XLogP3:

1.5

Appearance:

Tolazamide appears as white to off-white crystalline powder. Odorless or with a slight odor. (NTP, 1992)

Density:

1.2228 (rough estimate)

Melting Point:

170-173 °C

Boiling Point:

300°C (rough estimate)

Flash Point:

100 °C

Refractive Index:

1.6740 (estimate)

Water Solubility:

3.08e-01 g/L

Storage Conditions:

Refrigerator

Toxicity:

LD50 in rats, mice (mg/kg): >5000 orally, 2239 i.p. (Dulin)

Odor:

ODORLESS OR HAS SLIGHT ODOR

Dissociation Constants:

PKA @ 25 °C, 3.6; PKA @ 37.5 °C, 5.68

Collision Cross Section:

173.3 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Air and Water Reactions:

This chemical may be sensitive to prolonged exposure to air. Insoluble in water.

Reactive Group:

Amides and Imides

Reactivity Profile:

TOLAZAMIDE is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx). This chemical is incompatible with acids. (NTP, 1992).

See More Tolazamide Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Tolazamide Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Active Pharm Ingredients,Chemical Catalyst,Pharmaceutical Intermediates,Flavors and Fragrances,Agrochemicals,Chemical Pesticides

Location:
Zone K,Zwei Tianyuan Dushi Est,New Industial Park,High-tech Zone, Xian City,Shaanxi

Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
15 days

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
11-50

Year of Establishment:
2017

Company Certificates
- international trade license
- FSSC2000
Shaanxi Greenbo Biochem Co., Limited
is located in the High-Tech Zone of Xi'an, Shaanxi Province. which is a world-class innovation company and core competencies in the fields of health care and farm chemical. Since 2002 we are the high-tech corporation with GMP and ISO9001:2008 specializing in the production and research of farm chemical and its intermediates, Nutritional supplement and plant extract for pharmaceutical, Food, beverage, Cosmetic industry. With our innovative products, we are contributing to finding solutions to some of the major challenges of our time. The growing and increasingly aging world population requires improved medical care and an adequate supply of food. Greenbo is improving people’s quality of life by preventing, alleviating and treating diseases. And we are helping to provide a reliable supply of high quality green agricultural chemical, high-quality food, feed additive and plant-based raw materials. We develop new molecules for use in innovative products and solutions to improve health. By strict standing with the current GMP and tight QC procedures, with our skilled personal and special equipment, we saved the cost during production, make the manufacture effectiveness and also worked out with innovative pharmaceutical, food, cosmetic products. We also focus on the quality control and technology innovation. Greenbo R& D Center has a dedicated professional team tracking every step in our production. Up to now our center has developed long term cooperation with the professors, experts from Xi'an Jiao Tong University, Zhejiang University, engaging to the research and develop of the latest technology and new products.

At Greenbo, we insist the principle of Top quality, Excellent Service, Outstanding technology innovation, Constantly develop. And our consistent objective is mutually benefit and win-win with customers and developing together, our code of practice for customer service is to make conveniences and benefit for customers; we do concern for customers, and searching solution of difficult problems from market feedbacks, so as to provide better service and tailored technical support, expanding our market and establish reputations. Our sales network covers 29 provinces in china. And internationally, our products were exported to Europe, America, Australia, Russia, Japan, Korea, and southeast Asia. Good commercial integrity and stable customer group make Greenbo to extend our business to the whole world. We sincerely welcome you to join us and create and even brighter future with you together.
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Tolazamide 99% white powder GB0234 Greenbo

Product Details

Seller Information

High quality USP/EP/BP 20 GMP DMF FDA Tolazamide CAS NO 1156-19-0 producer

Shaanxi Greenbo Biochem Co., Limited

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

Shaanxi Greenbo Biochem Co., Limited

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