![cis-4-[(4-Chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexanepropanoic acid buy - large image1](https://file.echemi.com/fileManage/upload/cas/485/51f01491-ff02-450a-b724-61ca733eb069.png)
![cis-4-[(4-Chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexanepropanoic acid buy - image2](https://file.echemi.com/fileManage/upload/goodpicture/20221027/s20221027180418506.jpg "cis-4-[(4-Chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexanepropanoic acid")
![cis-4-[(4-Chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexanepropanoic acid buy - large image2](https://file.echemi.com/fileManage/upload/goodpicture/20221027/cis-4-4-chlorophenylsulfonyl-4-2-5-difluorophenylcyclohexanepropanoic-acid_b20221027180418063.jpg "cis-4-[(4-Chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexanepropanoic acid")
cis-4-[(4-Chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexanepropanoic acid
GMP HALAL KOSHER ISO FDA
471905-41-6
Industrial Grade
99%
Dideu
25kg/Cardboard Drum
Yes
2022-11-03
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
-
Product Details
-
Seller Information
-
DescriptionECHEMI Editorial ReferenceMK-0752 is a moderately potent γ-secretase inhibitor, which reduces Aβ40 production with IC50 of 5 nM.IC50 value: 5 nM (reduces Aβ40 production) [1]Target: γ-secretasein vitro: MK-0752 is identified as a moderately potent γ-secretase inhibitor, which reduces Aβ40 in a dose-dependent manner with an IC50 of 5 nM in human SH-SY5Y cells [1]. In vitro, MK-0752 blocks Notch-intracellular domain (ICD) cleavage and its subsequent nuclear translocation [2]. in vivo: MK-0752 (240 mg/kg) reduces th
Mk 0752 is under investigation in clinical trial NCT00572182 (MK0752 in Treating Young Patients With Recurrent or Refractory CNS Cancer).|Notch Signaling Pathway Inhibitor MK0752 is a synthetic small molecule with potential antineoplastic activity. MK0752 inhibits the Notch signaling pathway, which may result in induction of growth arrest and apoptosis in tumor cells in which the Notch signaling pathway is overactivated. The Notch signaling pathway plays an important role in cell-fate determination, cell survival, and cell proliferation.CertificatesBasic Info-
Product Name:
cis-4-[(4-Chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexanepropanoic acid
Other Name:cis-4-[(4-Chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexanepropanoic acid;Cyclohexanepropanoic acid, 4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)-, cis-;MK-0752/MK0752;3-(cis-4-((4-Chlorophenyl)sulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)propanoic acid;3-((1r,4s)-4-(4-chlorophenylsulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)propanoic acid;cis-4-[(4-Chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexanepropanoic acidMK-0752;MK-0752, >=98%
CAS No.:471905-41-6
Molecular Formula:C21H21ClF2O4S
InChIKeys:XCGJIFAKUZNNOR-UHFFFAOYSA-N
Molecular Weight:443
Exact Mass:442.081726
UNII:9JD9B4S53T
NCI Thesaurus Code:C49175
HScode:29163990
Categories:
Characteristics-
PSA:
79.8
XLogP3:4.7
Density:1.4±0.1 g/cm3
Flash Point:326.9±31.5 °C
Refractive Index:1.569
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
-
-
Seller Information
-
Business Type:
Manufactory
-
Main Products:
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
-
Location:
https://www.dideu.com/en/
-
Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
-
Average lead Time:
7 days
-
Total Annual Revenue:
Above $100 million
-
Total Employees:
Above 1000
-
Year of Establishment:
2016
Company Certificates-
![Shaanxi Dideu Medichem Co. LtdISO Certificate]( "ISO Certificate")
ISO Certificate
-
![Shaanxi Dideu Medichem Co. LtdREACH]( "REACH")
REACH
">Company Profile -
-
Country Product Purchase Quantity Date Posted Post an enquiry for this product
More from this Seller
-
-
![Polyquaternium-10 99%]( "Polyquaternium-10 99%")
-
Polyquaternium-10 99%
/ 99%
-
-
-
![VINYLOXYTRIMETHYLSILANE 99% liquid 6213-94-1 Dideu]( "VINYLOXYTRIMETHYLSILANE 99% liquid 6213-94-1 Dideu")
-
VINYLOXYTRIMETHYLSILANE 99% liquid 6213-94-1 Dideu
Reagent Grade / 99%
-
-
-
![POLY(VINYL FORMAL)]( "POLY(VINYL FORMAL)")
-
POLY(VINYL FORMAL)
Chemical Grade / 95%
-
-
-
![Acetic acid, ion(1-) (8CI,9CI)]( "Acetic acid, ion(1-) (8CI,9CI)")
-
Acetic acid, ion(1-) (8CI,9CI)
Pharmaceutical Grade / 99%
-
-
-
![4-bromo-1-ethyl-3-phenyl-1H-pyrazole-5-carboxylic acid]( "4-bromo-1-ethyl-3-phenyl-1H-pyrazole-5-carboxylic acid")
-
4-bromo-1-ethyl-3-phenyl-1H-pyrazole-5-carboxylic acid
Industrial Grade / 99%
-
