Rivastigmine 99% high purity certified Professional Producer Greenbo
123441-03-2
Pharmaceutical Grade
99%
Shanghai
Greenbo
25kg Drum
2022-07-31
Active Pharm Ingredients,Chemical Catalyst,Pharmaceutical Intermediates,Flavors and Fragrances,Agrochemicals,Chemical Pesticides
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceChEBI: A carbamate ester obtained by formal condensation of the carboxy group of ethyl(methyl)carbamic acid with the phenolic OH group of 3-[(1S)-1-(dimethylamino)ethyl]phenol. A reversible cholinesterase inhibitor.Rivastigmine (Exelon, EA 713) is apseudoirreversible noncompetitive carbamate inhibitor ofAChE. Although the half-life is approximately 2 hours,the inhibitory properties of this agent last for 10 hours becauseof the slow dissociation of the drug from the enzyme.The Food and Drug Admi
Solid
Rivastigmine is a carbamate ester obtained by formal condensation of the carboxy group of ethyl(methyl)carbamic acid with the phenolic OH group of 3-[(1S)-1-(dimethylamino)ethyl]phenol. A reversible cholinesterase inhibitor. It has a role as an EC 3.1.1.8 (cholinesterase) inhibitor, a neuroprotective agent and a cholinergic drug. It is a carbamate ester and a tertiary amino compound. It is a conjugate base of a rivastigmine(1+).|Rivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type. Rivastigmine is a cholinesterase inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase.|Rivastigmine is a Cholinesterase Inhibitor. The mechanism of action of rivastigmine is as a Cholinesterase Inhibitor.|Rivastigmine is an oral acetylcholinesterase inhibitor used for therapy of Alzheimer disease. Rivastigmine is associated with a minimal rate of serum enzyme elevations during therapy and is a rare cause of clinically apparent liver injury.|A carbamate-derived reversible CHOLINESTERASE INHIBITOR that is selective for the CENTRAL NERVOUS SYSTEM and is used for the treatment of DEMENTIA in ALZHEIMER DISEASE and PARKINSON DISEASE.Basic Info-
Product Name:
Rivastigmine
Other Name:Carbamic acid,N-ethyl-N-methyl-,3-[(1S)-1-(dimethylamino)ethyl]phenyl ester;Carbamic acid,ethylmethyl-,3-[1-(dimethylamino)ethyl]phenyl ester,(S)-;Carbamic acid,ethylmethyl-,3-[(1S)-1-(dimethylamino)ethyl]phenyl ester;SDZ 212-713;Rivastigmine;Exelon;ENA 713 free base;S-Rivastigmine;Prometax;Rivastach;[3-[(1S)-1-(Dimethylamino)ethyl]phenyl] N-ethyl-N-methylcarbamate;Nimvastid
CAS No.:123441-03-2
Molecular Formula:C14H22N2O2
InChIKeys:InChIKey=XSVMFMHYUFZWBK-NSHDSACASA-N
Molecular Weight:250.34
Exact Mass:250.34
EC Number:1308068-626-2
UNII:PKI06M3IW0
DSSTox ID:DTXSID7023564
ATC Code:N06DA03|N - Nervous system
HScode:2924296000
Categories:
Characteristics-
PSA:
32.8
XLogP3:2.3
Appearance:Solid
Density:1.038±0.06 g/cm3(Predicted)
Boiling Point:316.2±34.0 °C(Predicted)
Flash Point:145℃
Refractive Index:1.518
Water Solubility:2.04e+00 g/L
Storage Conditions:-20°C
Specific rotation:D20 -32.1° (c = 5 in ethanol)
Collision Cross Section:165 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)]
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 3, Oral
Acute toxicity - Category 4, Dermal
Acute toxicity - Category 4, Inhalation
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Danger
Hazard statement(s) H301 Toxic if swallowed
H312 Harmful in contact with skin
H332 Harmful if inhaled
H411 Toxic to aquatic life with long lasting effects
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P317 Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P391 Collect spillage.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Active Pharm Ingredients,Chemical Catalyst,Pharmaceutical Intermediates,Flavors and Fragrances,Agrochemicals,Chemical Pesticides
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Location:
Zone K,Zwei Tianyuan Dushi Est,New Industial Park,High-tech Zone, Xian City,Shaanxi
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Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
15 days
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2017
Company Certificates-
international trade license
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FSSC2000
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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