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N-(4-Methoxyphenyl)-N,2-dimethylquinazolin-4-amine
N-(4-Methoxyphenyl)-N,2-dimethylquinazolin-4-amine
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CAS No.:
827031-83-4
Port:
shanghai
Packaging:
25kg/ea
Sample Available:
Yes
Price valid (until):
2023-12-30
Company Type:
Manufactory
Location:
China
Payment Terms:
TT against copy of documents
Average Lead Time:
5 days
Qualification:
Main Products:
BBiochemicals,Peptides,Silicones,Pharmaceuticals,Building blocks,Intermediates
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceAntineoplastic; a small-molecule inhibitor of microtubule formation that is not a substrate for multidrug resistance pumps.|Verubulin is a quinazoline derivative with potential antineoplastic activities. Verubulin binds to and inhibits tubulin polymerization and interrupts microtubule formation, resulting in disruption of mitotic spindle assembly, cell cycle arrest in the G2/M phase, and cell death. This agent is not a substrate for several subtypes of multidrug resistance ABC transporters, and may be useful for treating multidrug resistant tumors. In addition, as a vascular disrupting agent, verubulin disrupts tumor microvasculature specifically, which may result in acute ischemia and massive tumor cell death. In addition, verubulin is able to cross the blood-brain barrier and accumulate in the brain.Basic Info
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Product Name:
Verubulin
Other Name:Verubulin;827031-83-4;N-(4-Methoxyphenyl)-N,2-dimethylquinazolin-4-amine;Azixa;MPC 6827;UNII-X97O9FTB92;MPC-6827;MPC-6827 (hydrochloride);MX-128495;X97O9FTB92
CAS No.:827031-83-4
Molecular Formula:C17H17N3O
InChIKeys:SNHCRNMVYDHVDT-UHFFFAOYSA-N
Molecular Weight:279.34
Exact Mass:279.137162174
UNII:X97O9FTB92
NCI Thesaurus Code:C96747
Categories:
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Seller Information
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Business Type:
Manufactory
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Main Products:
BBiochemicals,Peptides,Silicones,Pharmaceuticals,Building blocks,Intermediates
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Location:
#101,Buliding1#,Jinsexixi,Xihu District,Hangzhou City, Zhejiang Province,CHINA
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Payment Terms:
TT against copy of documents
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Average lead Time:
5 days
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Total Annual Revenue:
$10 million-$25 million
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Total Employees:
11-50
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Year of Establishment:
2012
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