Chlorzoxazone
5 Inquiries
95-25-0
99%
Bottle,barrel,cargo,container,etc.
2026-10-15
Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals
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Product Description
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Seller Information
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Inquiry History
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DescriptionKeywords
Chlorzoxazone
95-25-0
C7H4ClNO2
Quick DetailsProName:Chlorzoxazone
CasNo:95-25-0
Molecular Formula:C7H4ClNO2
Appearance:powder, or liquid
Application:Pharmaceuticals, intermediates, APIs, custom synthesis, chemicals
DeliveryTime:5-7 Days
PackAge:Bottle, barrel, cargo, container, etc.
Port:Shanghai
Purity:99
Storage:Stored in room temperature, ventilated place
Transportation:By air, ship, express, etc.
LimitNum:0
Grade:Industrial Grade
SuperiorityBest Seller, High Quality, Competitive Price, Fast Delivery, Quick Response
DetailsLEAPChem supplies high quality Pharmaceuticals, intermediates, APIs, custom synthesis, fine chemicals and other industrial chemicalsECHEMI Editorial ReferenceChlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort. It acts on the spinal cord by depressing reflexes.Chlorzoxazone is currently being used as a marker substrate in vitro/vivo studies to quantify cytochrome P450 2E1 (CYP2E1) activity in humans.
Solid
Chlorzoxazone is a member of the class of 1,3-benzoxazoles that is 1,3-benzoxazol-2-ol in which the hydrogen atom at position 5 is substituted by chlorine. A centrally acting muscle relaxant with sedative properties, it is used for the symptomatic treatment of painful muscle spasm. It has a role as a muscle relaxant and a sedative. It is a member of 1,3-benzoxazoles, an organochlorine compound and a heteroaryl hydroxy compound.|A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)|Chlorzoxazone is a Muscle Relaxant. The physiologic effect of chlorzoxazone is by means of Centrally-mediated Muscle Relaxation.|Chlorzoxazone is a centrally acting muscle relaxant commonly used for low back pain. Chlorzoxazone has been linked to rare instances of acute liver injury, a few of which have been fatal.|Chlorzoxazone is a benzoxazolone derivative with mild sedative and centrally-acting muscle relaxant activities. Although its exact mechanism of action is unknown, chlorzoxazone (CZ) appears to act at the spinal cord and subcortical levels of the brain to inhibit multisynaptic reflex arcs involved in producing and maintaining muscle spasms. This agent is extensively hydroxylated by cytochrome P450 2E1 (CYP2E1) to 6-hydroxychlorzoxazone (HCZ),11,12 which is subsequently glucuronidated and eliminated renally. Highly selective for CYP2E1, CZ may be used as a selective probe for phenotyping CYP2E1 in humans; the ratio of HCZ-to-CZ plasma concentrations obtained 2 to 4 hours after oral administration of CZ may be used as a phenotypic measure of CYP2E1 enzymatic activity.Basic Info-
Product Name:
Chlorzoxazone
Other Name:2(3H)-Benzoxazolone,5-chloro-;2-Benzoxazolinone,5-chloro-;5-Chloro-2(3H)-benzoxazolone;5-Chlorobenzoxazolidone;5-Chloro-2-benzoxazolinone;Chloroxazone;Chlorzoxazone;Paraflex;Solaxin;Myoflexine;5-Chlorobenzoxazolone;5-Chloro-2-benzoxazolone;5-Chloro-2-benzoxazolol;5-Chloro-2-hydroxybenzoxazole;2-Hydroxy-5-chlorobenzoxazole;Biomioran;Mioran;Miotran;Myoflexin;Neoflex;Escoflex;Pathorysin;Parafon Forte DSC;NSC 26189;5-Chloro-2-oxo-3H-benzoxazole;5-Chloro-3H-benzoxazol-2-one;5-Chloro-1,3-benzoxazol-2(3H)-one;Parfon-forte;Cipzox;32850-84-3
CAS No.:95-25-0
Molecular Formula:C7H4ClNO2
InChIKeys:InChIKey=TZFWDZFKRBELIQ-UHFFFAOYSA-N
Molecular Weight:169.57
Exact Mass:169.57
EC Number:202-403-9
UNII:H0DE420U8G
NSC Number:756693|26189
DSSTox ID:DTXSID9022813
NCI Thesaurus Code:C28926
ATC Code:M - Musculo-skeletal system
HScode:2934999090
Categories:
Characteristics-
PSA:
38.3
XLogP3:1.8
Appearance:white to off-white Powder
Density:1.5±0.1 g/cm3
Melting Point:191.5 °C
Flash Point:157.5±25.7 °C
Refractive Index:1.674
Water Solubility:H2O: 0.1 g/100 mL;DMSO: soluble 50mg/mL, clear
Storage Conditions:-20°C Freezer
Toxicity:Oral-rat LD50: 763 mg/kg; Oral-Mouse LD50: 440 mg/kg
Flammability characteristics:Thermal decomposition releases toxic nitrogen oxides and chloride fumes
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity â single exposure, Category 3
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals
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Location:
Room A, 23rd Floor, No. 609 Yan'an Road, Gongshu District, Hangzhou, Zhejiang
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Payment Terms:
TT against copy of documents,D/P,L/C
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Average lead Time:
5
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Total Annual Revenue:
Above $100 million
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Year of Establishment:
2020
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Certifications:
ISO
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Methodology: Sound & Stable; Active & Innovative.
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Inquiry History5 Inquiries
Country Product Purchase Quantity Date Posted 
Yemen
Chlorzoxazone
100 KG Dec 14, 2023 
India
Chlorzoxazone
56 KG Apr 21, 2026 
Canada
Methyltrienolone, metribolone
10 G Aug 16, 2026 
Netherlands
Metribolone
1 G Jun 15, 2026
India
CHLORZOXAZONE IP
100.00 KG Jun 16, 2025 Post an enquiry for this product
