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Indisulam

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CAS No.:

165668-41-7

Content:

99%

Packaging:

Bottle,barrel,cargo,container,etc.

Sample Available:

Yes

Price valid (until):

2026-10-27

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HANGZHOU LEAP CHEM CO., LTD.

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,D/P,L/C

Average Lead Time:

5 days

Qualification:

Main Products:

Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals

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Product Description
Seller Information

Description

Keywords

165668-41-7

Indisulam

C14H12ClN3O4S2

Quick Details

ProName:
Indisulam

CasNo:
165668-41-7

Molecular Formula:
C14H12ClN3O4S2

Appearance:
powder, or liquid

Application:
Pharmaceuticals, intermediates, APIs, custom synthesis, chemicals

DeliveryTime:
5-7 Days

PackAge:
Bottle, barrel, cargo, container, etc.

Port:
Shanghai

Purity:
99

Storage:
Stored in room temperature, ventilated place

Transportation:
By air, ship, express, etc.

LimitNum:
0

Grade:
Industrial Grade

Superiority

Best Seller, High Quality, Competitive Price, Fast Delivery, Quick Response

Details

LEAPChem supplies high quality Pharmaceuticals, intermediates, APIs, custom synthesis, fine chemicals and other industrial chemicals

ECHEMI Editorial Reference

Indisulam is a chloroindole that is 3-chloro-1H-indole substituted by a [(4-sulfamoylphenyl)sulfonyl]nitrilo group at position 7. It is a carbonic anhydrase inhibitor and a potential anti-cancer agent currently in clinical development. It has a role as an EC 4.2.1.1 (carbonic anhydrase) inhibitor and an antineoplastic agent. It is a chloroindole, a sulfonamide and an organochlorine compound.|Indisulam is a novel sulfonamide compound with potential antineoplastic activity. Indisulam inhibits cyclin-dependent kinases (CDK), which regulate cell cycle progression and are usually over-expressed in cancerous cells. Inhibition of CDK results in G1/S phase arrest of the cell cycle, and may lead to induction of apoptosis and inhibition of tumor cell proliferation. In addition, indisulam also inhibits carbonic anhydrases (CA), especially isoforms IX and XII that are involved in aqueous humor production and are highly overexpressed in some types of cancers. Inhibition of CA IX and XII results in interference with ion exchange and pH in hypoxic tumor tissue and preventing chemoresistance to weakly basic antineoplastic agents.

Basic Info

Product Name:
Indisulam

Other Name:
1,4-Benzenedisulfonamide,N1-(3-chloro-1H-indol-7-yl)-;1,4-Benzenedisulfonamide,N-(3-chloro-1H-indol-7-yl)-;N1-(3-Chloro-1H-indol-7-yl)-1,4-benzenedisulfonamide;E 7070;Indisulam

CAS No.:
165668-41-7

Molecular Formula:
C14H12ClN3O4S2

InChIKeys:
InChIKey=SETFNECMODOHTO-UHFFFAOYSA-N

Molecular Weight:
385.8 g/mol

Exact Mass:
385.85

UNII:
WJ98J3NM90

DSSTox ID:
DTXSID50168008

NCI Thesaurus Code:
C25797

Categories:

Characteristics

PSA:
139 Å²

Melting Point:
242-243 °C (decomp) @ Solvent: Ethanol, Water

See More Indisulam Properties 
Seller Information

Business Type:
Trader

Main Products:
Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals

Location:
Room A, 23rd Floor, No. 609 Yan'an Road, Gongshu District, Hangzhou, Zhejiang

Payment Terms:
TT against copy of documents,D/P,L/C

Average lead Time:
5 days

Total Annual Revenue:
Above $100 million

Year of Establishment:
2020

Company Certificates
- ISO
Company Profile
LEAPChem is a specialized fine chemical supplier for research, development and production.
LEAPChem provides nearly 200,000 rare and innovative chemical products to support the evolving needs of our customers in research & bulk manufacturing activities.
As a highly customer-oriented enterprise, we are committed to providing high-quality customer services and products to our global customers in a cost-effective and efficient manner.
Our client list includes many major pharmaceutical and science companies, universities, research institutions and chemical catalogue companies.

Methodology: Sound & Stable; Active & Innovative.
Attitude: Conscientious; Ingenious.
Goals: Customer's Satisfaction

We regard client's success as our success.
At LEAPChem, we strive to be the preferred supplier for efficiency increasing and cost lowering in your Research & Production.
To achieve this strategic vision, we always push ourselves to exceed our customer's requirement. By focusing on the aim of 'Beyond Your Expectation', we continually expand our product lines, and enhance our systematic management and human resources.
Welcome to contact us and we look forward to becoming your reliable and preferred partner.
LEAPChem is a specialized fine chemical supplier for research, development and production.
LEAPChem provides nearly 200,000 rare and innovative chemical products to support the evolving needs of our customers in research & bulk manufacturing activities.
As a highly customer-oriented enterprise, we are committed to providing high-quality customer services and products to our global customers in a cost-effective and efficient manner.
Our client list includes many major pharmaceutical and science companies, universities, research institutions and chemical catalogue companies.

Methodology: Sound & Stable; Active & Innovative.
Attitude: Conscientious; Ingenious.
Goals: Customer's Satisfaction

We regard client's success as our success.
At LEAPChem, we strive to be the preferred supplier for efficiency increasing and cost lowering in your Research & Production.
To achieve this strategic vision, we always push ourselves to exceed our customer's requirement. By focusing on the aim of 'Beyond Your Expectation', we continually expand our product lines, and enhance our systematic management and human resources.
Welcome to contact us and we look forward to becoming your reliable and preferred partner.
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Indisulam

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