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Progestogen Chlormadinone acetate,Gestafortin 98% Powder 302-22-7 Senwayer

Name: Progestogen Chlormadinone acetate,Gestafortin 98% Powder 302-22-7 Senwayer
Brand: Senwayer
SKU: pr2208121849
Price: 5 USD
Availability: InStock

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CAS No.:

302-22-7

Grade:

Top Product

Content:

98%

Port:

Wuhan

Brand:

Senwayer

Packaging:

1KG per foil bag, 25KG per drum.

Price valid (until):

2024-04-26

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Dingwang Technology (Wuhan) Co., Ltd.

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,L/C

Average Lead Time:

10 days

Qualification:

Main Products:

API,nutrition supplements,plant extract,peptide,HCG,6-Aminocaproic acid

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Product Description
Seller Information
Inquiry History

Description

Product Detail

MF	C23H29ClO4
MW	404.93
Appearance	White powder
Origin	China

Orally active progesteron with antiandrogenic activity; has been used in combinations as an oral contraceptive. Progestogen; antineoplastic (hormonal)

ECHEMI Editorial Reference

Chlormadinone acetate is a steroidal progestin, with antiandrogen and antiestrogenic effects.
Chlormadinone acetate is a corticosteroid hormone.|Chlormadinone Acetate is the actetate salt form of chlormadinone, a synthetic progestin with antiandrogenic and antigonadotropic effects. Chlormadinone acetate (CMA) is a potent progesterone receptor (PR) agonist, a partial androgen receptor (AR) antagonist and a weak glucocorticoid receptor (GR) antagonist. Chlormadinone binds to PRs, which induces the expression of progesterone-responsive genes. In addition, chlormadinone blocks ARs in target organs and reduces the activity of skin 5 alpha-reductase; thus inhibiting androgen production and signaling. Through the negative feedback action on the hypothalamus-pituitary system, chlormadinone also suppresses gonadotropin secretion, which prevents ovarian and adrenal androgen production. Therefore, this agent decreases endometrial thickness, increases the viscosity of cervical mucus, inhibits ovulation and suppresses follicular growth and maturation.|An orally active synthetic progestational hormone used often in combinations as an oral contraceptive (CONTRACEPTIVES, ORAL).

Certificates

Basic Info

Product Name:

Chlormadinone acetate

Other Name:

Pregna-4,6-diene-3,20-dione,17-(acetyloxy)-6-chloro-;Pregna-4,6-diene-3,20-dione,6-chloro-17-hydroxy-,acetate;17-(Acetyloxy)-6-chloropregna-4,6-diene-3,20-dione;RS 1280;17-Acetoxy-6-chloro-6-dehydroprogesterone;CAP;Chlormadinone acetate;6-Chloro-17-acetoxy-4,6-pregnadiene-3,20-dione;6-Chloro-Δ6-17-acetoxyprogesterone;6-Chloro-Δ6-dehydro-17-acetoxyprogesterone;6-Chloro-6-dehydro-17-acetoxyprogesterone;6-Chloro-6-dehydro-17α-acetoxyprogesterone;6-Chloro-17α-hydroxypregna-4,6-diene-3,20-dione acetate;6-Chloro-17α-hydroxy-Δ6-progesterone acetate;6-Chloro-Δ4,6-pregnadien-17α-ol-3,20-dione 17-acetate;6-Chloro-pregna-4,6-dien-17α-ol-3,20-dione acetate;6-Dehydro-6-chloro-17α-acetoxyprogesterone;Lormin;Lutinyl;Skedule TM;Matrol;6-Chloro-17-hydroxypregna-4,6-diene-3,20-dione acetate;Ay 13390-6;6-Chloro-17α-hydroxy-4,6-pregnadiene-3,20-dione 17-acetate;Gestafortin;6-Chloro-17α-acetoxy-4,6-pregnadiene-3,20-dione;6-Chloro-6,7-dehydro-17-acetoxyprogesterone;6-Chloro-Δ6-[17α]acetoxyprogesterone;Chlormadinon acetate;17-Acetoxy-6-chloropregna-4,6-diene-3,20-dione;17α-Acetoxy-6-chloro-6,7-dehydroprogesterone;Luteran;Lutoral (Syntex);Normenon;Menstridyl;Cero;Verton;17α-Acetoxy-6-chloro-4,6-pregnadiene-3,20-dione;Synchrosyn P;Bovisynchron;Traslan;Clordion;Retex;Synchrosyn;Prostal;NSC 92338;Natrol;Lutoral;Fertiletten;Chronosyn;Cyclonorm;Bellissima

CAS No.:

302-22-7

Molecular Formula:

C23H29ClO4

InChIKeys:

InChIKey=QMBJSIBWORFWQT-DFXBJWIESA-N

Molecular Weight:

404.93

Exact Mass:

404.93

EC Number:

206-118-0

UNII:

0SY050L61N

NSC Number:

92338

DSSTox ID:

DTXSID6020274

NCI Thesaurus Code:

C365

Color/Form:

Crystals from menthanol or ether|White to light-yellow...crystals

HScode:

29372390

Categories:

Other Chemical Drugs

Characteristics

PSA:

60.4

XLogP3:

3.6

Appearance:

crystalline solid

Density:

1.2±0.1 g/cm3

Melting Point:

212-214 °C

Boiling Point:

512.5°C at 760 mmHg

Flash Point:

172.5±29.1 °C

Refractive Index:

1.563

Water Solubility:

In water, 0.324 mg/L at 25 deg C (est)

Storage Conditions:

-20°C Freezer

Vapor Pressure:

3.22X10-9at 25 deg C (est)

Toxicity:

Oral-rat LD50: > 10000 mg/kg; Oral-Mouse LD50: > 15000 mg/kg

Flammability characteristics:

Thermal decomposition to emit toxic chloride fumes

Specific rotation:

D +6° (c = 1 in CHCl3)

Odor:

Odorless

Henrys Law Constant:

Henry's Law constant = 5.64X10-10 atm-cu m/mol at 25 °C (est)

Collision Cross Section:

197 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]|199.43 Å² [M+H]+

See More Chlormadinone acetate Properties 

Hazard Identification

Classification of the substance or mixture

Carcinogenicity, Category 2

Reproductive toxicity, Category 1B

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H351 Suspected of causing cancer H360 May damage fertility or the unborn child
Prevention	P203 Obtain, read and follow all safety instructions before use. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P318 IF exposed or concerned, get medical advice.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Keep container tightly closed in a dry and well-ventilated place. Light sensitive. Keep in a dry place.

See More Chlormadinone acetate Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
API,nutrition supplements,plant extract,peptide,HCG,6-Aminocaproic acid

Location:
Room 707, Block A, Zhongxing Times Digital Trade Port, No. 79 Xudong Street, Hongshan District, Wuhan City

Payment Terms:
TT against copy of documents,L/C

Average lead Time:
10 days

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
51-100

Year of Establishment:
2020

Company Certificates
- Verified supplier certificate
- SGS
Dingwang Technology (Wuhan) Co., Ltd located in the predominant WuHan City where is a traffic hinge of China,specilize in producing and developing pharmaceutical & its intermediates, Peptide, Nutritional supplements,food additive, Plant extracts,and in distributing the products of our own company and affiliated enterprises.
We have set up R&D center, quality inspection center and manufacturing site in Wuhan, Jiangsu and others places.
Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. Meanwhile, we possess of complete Q.A. and Q.C. system, supply chemical products with good quality and custom-tailored products according to our clients' requirement.
We have professional sales team, focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market , our products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc.
With our constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.

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Progestogen Chlormadinone acetate,Gestafortin 98% Powder 302-22-7 Senwayer

Product Description

Seller Information