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100% Original China Nicotinamide Vitamin B3 CAS 98-92-0

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CAS No.:

98-92-0

Grade:

Cosmetics Grade

Content:

100%

Port:

Tianjin,Shanghai

Brand:

YR Chemspec

Packaging:

25kgs Drum

Price valid (until):

2026-05-01

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Tianjin YR ChemSpec Technology Co.,Ltd.

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Hydroxypinacolone Retinoate 10%,Hydroxypinacolone Retinoate,Niacinamide,DL-Panthenol,Ascorbyl Tetraisopalmitate,Tetrahexyldecyl Ascorbate

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Product Description
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Description

Nicotinaminde/Vitamin B3/Vitamin PP

Nicotinamide(Vitamin B3, Vitamin PP) is a very stable vitamin which offers a wide range of benefits. Nicotinamide is a component of NAD and NADP, essential coenzymes in ATP production, also having a central role in DNA repair and skin homeostasis. It is a significant niacin derivative, mainly occurring in many organisms. Nicotinamide can produce coenzyme Ⅰ and Ⅱ when it reacts with ribose, adenine and phosphoric acid. Also it boosts the synthesis of DNA, fats and proteins and improves the energy metabolism of cells. So it can greatly prevent melanin deposition, and reduce discoloration. It has an effective whitening function. Nowadays, as a natural cosmetics ingredient, it is widely applied in skin and hair care products.

Shop 100% Original China Nicotinamide Vitamin B3 CAS 98-92-0-Detailed Image 1

In the dynamic world of cosmetic ingredients, Niacinamide (vitamin B3) stands out as a versatile, science-backed staple. This water-soluble vitamin, celebrated for its gentle yet potent performance, addresses multiple skin concerns—from barrier repair to anti-aging—making it a must-have for brands targeting diverse consumer needs. Its ability to work across all skin types, including sensitive and acne-prone, has solidified its status as a “universal skincare ingredient.”

1. Strengthens the Skin Barrier: Defense Against Irritation

Niacinamide’s primary strength lies in fortifying the stratum corneum, the skin’s outermost protective layer. It boosts the production of ceramides, lipids, and natural moisturizing factors (NMFs), reducing transepidermal water loss (TEWL) by up to 27% (per clinical studies). This not only locks in hydration but also shields skin from environmental irritants like pollution, cold weather, and harsh cleansers. For sensitive skin or those recovering from procedures (e.g., chemical peels), it calms redness and stinging by regulating inflammatory pathways—eliminating the “sensitivity barrier” that limits use of other actives.

2. Controls Oil & Fights Acne

For oily and acne-prone skin, Niacinamide is a game-changer. It regulates sebum production by inhibiting the activity of sebaceous glands, reducing shine and preventing clogged pores. It also has antimicrobial properties that target Cutibacterium acnes, the bacteria linked to breakouts, while minimizing post-acne redness (PIE) and hyperpigmentation (PIH). Unlike drying acne treatments (e.g., benzoyl peroxide), it maintains the skin’s barrier integrity, avoiding over-drying or irritation—making it suitable for long-term use.

3. Brightens & Evens Skin Tone

Niacinamide is a top-tier brightening ingredient, addressing discoloration at multiple stages. It inhibits melanosome transfer (the process that moves pigment to skin cells), fades existing sunspots and melasma, and boosts cell turnover to reveal brighter, more even skin. Clinical data shows 5% Niacinamide reduces hyperpigmentation by 20–30% in 8–12 weeks, with no risk of “rebound” pigmentation. Its gentle profile also makes it a safer alternative to harsh brighteners like hydroquinone.

4. Reduces Signs of Aging

Beyond barrier care, Niacinamide delivers visible anti-aging results. It stimulates collagen synthesis to firm skin and smooth fine lines, particularly around the eyes and forehead. It also improves skin elasticity by boosting elastin production and reduces the appearance of pores by tightening their structure. Unlike retinol, it requires no “tolerance building” and works well for mature skin without causing dryness or peeling.

5. Formulation Versatility & Stability

Cosmetic formulators prize Niacinamide for its adaptability. It is stable across a wide pH range (4.0–7.0), compatible with water-based and oil-based products (serums, moisturizers, sunscreens), and blends seamlessly with other actives:

Vitamin C: Enhances brightening and antioxidant protection without irritation.

Hyaluronic Acid: Amplifies hydration for plumper skin.

Retinol: Reduces retinol-induced dryness and sensitivity.

Its stability also eliminates the need for opaque packaging or special handling, simplifying production and lowering costs.

Aligned with clean beauty trends, Niacinamide is synthetically produced via eco-friendly processes, free from parabens and sulfates, and cruelty-free. For brands and consumers alike, it proves that effective skincare doesn’t need to be complex—one ingredient can deliver barrier repair, oil control, brightening, and anti-aging benefits. As the demand for multi-tasking, gentle ingredients grows, Niacinamide remains at the forefront of cosmetic innovation.

1. Strengthens the Skin Barrier: Defense Against Irritation

2. Controls Oil & Fights Acne

3. Brightens & Evens Skin Tone

4. Reduces Signs of Aging

5. Formulation Versatility & Stability

Vitamin C: Enhances brightening and antioxidant protection without irritation.

Hyaluronic Acid: Amplifies hydration for plumper skin.

Retinol: Reduces retinol-induced dryness and sensitivity.

Its stability also eliminates the need for opaque packaging or special handling, simplifying production and lowering costs.

Key Technical Parameters:

Appearance	White crystalline powder
Assay	99.0~101.0%
pH (10% aqueous solution)	5.5~7.5
Melting range	128.0~131.0℃
Residue on ignition	≤0.1%(wt%)
Heavy metals	≤20ppm
Identification	Complies
Readily carbonizable	Complies
Loss on drying	≤0.5%

Application:

• UV and blue light-stressed Skin Care

• Helps protect from UV and blue light damage for beautiful and healthy looking skin

• Reduces the appearance of lines and wrinkles

• Improves the elasticity of the skin

• Rebalances uneven skin tone

• Reduces discoloration

• Pollution Care

• Protects against damage from urban pollutants for beautiful and healthy skin

• Blemish Care

• Blemish-free, shine-free, refined skin appearance

• Resilience to external damage and reduced skin sensitivity

• Well moisturized skin, comfortable skin feeling

• Nicotinamide PC shows skin lightening properties versus placebo in 3D skin model.

Shop 100% Original China Nicotinamide Vitamin B3 CAS 98-92-0-Detailed Image 2

Benefits:

• Prevent melanin from depositing into keratinocytes

Skin will darken when melanin is delivered to keratinocytes. But Nicotinamide can act on generated melanin, and then efficiently prevent the transfer of 35% to 40% of melanin from melanocytes to horny cells. Hence, it can lessen excessive pigmentation. Clinical tests have suggested that Nicotinamide face cream can obviously reduce the brown spots ‘ number and area.

• Accelerate the metabolism of melanocytes

Nicotinamide is directly absorbed by cells owing to its small molecules. Nicotinamide can penetrate the inner layer of the skin within 2 hours. Using Nicotinamide to the skin can form energy molecules in human body quickly. It can penetrate the stratum corneum to the connective tissue and fibers between the dermis; and then it directly gets in the bottom of the cell to facilitate the metabolism of cells.

• Promote synthesis of cortical proteins on skin

Nicotinamide synthesizes protein on the surface of skin. And it amends skin texture, and moisturizes skin. In 1990, European Patent 0-396-422 shows that it can whiten skin and exert sun block effect to add Nicotinamide, 0.1% to 5% silicone compound and UVA, UVB sunscreen into the cream formulation.

Certificates

Basic Info

Product Name:

Nicotinamide

Other Name:

NicotinamideForBiochemistry;NicotinamideB.P.,U.S.P.;Niacinamide/Nicotinamide;Nicotinamide(Niacinamide)Nicotinamide(Niacinamide)Bp/Usp;Nicotinamide,98%;Vitamin B3;Nicotinamidum;NIACINAMIDE USP GRANULAR

CAS No.:

98-92-0

Molecular Formula:

C6H6N2O

InChIKeys:

DFPAKSUCGFBDDF-UHFFFAOYSA-N

Molecular Weight:

122.12

BRN:

383619

EC Number:

202-713-4

TSCA:

TSCA listed

Color/Form:

white

HScode:

29362990

Categories:

Bleaching Agent

Characteristics

Density:

1.40

Melting Point:

128-131 °C(lit.)

Boiling Point:

150-160 °C

Refractive Index:

1.4660 (estimate)

Water Solubility:

1000 g/L (20 ºC)

Vapor Pressure:

0Pa at 25℃

Vapor Density:

4.22 (vs air)

Toxicity:

LD50 2.5~3.5 g/kg (rats, through the mouth).GRAS(FDA，§182.5535，2000).ADI is no special regulation (EEC, 1990).

Flammability characteristics:

Non flammable

Odor:

Odorless

PH:

6.0-7.5 (50g/l, H2O, 20℃)

PKA:

3.3(at 20℃)

Henrys Law Constant:

3.4×106mol/(m3Pa) at 25℃, HSDB (2015)

Air and Water Reactions:

Water soluble.

Reactivity Profile:

An amine and amide. Acts as a weak base in solution. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

Autoignition Temperature:

480 °C

Critical Temperature & Pressure:

2-8°C

See More Nicotinamide Properties 

Hazard Identification

Classification of the substance or mixture

Eye irritation, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H319 Causes serious eye irritation
Prevention	P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Prevent deposition of dust. Closed system, dust explosion-proof electrical equipment and lighting. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Separated from oxidants.

See More Nicotinamide Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Hydroxypinacolone Retinoate 10%,Hydroxypinacolone Retinoate,Niacinamide,DL-Panthenol,Ascorbyl Tetraisopalmitate,Tetrahexyldecyl Ascorbate

Location:
908,Changqing Building,Weishan-Nan Road,Jinnan District,Tianjin,China 300350

Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$5 million-$10 million

Total Employees:
51-100

Year of Establishment:
2016

Certifications:
ISO9001,ISO9001

YR Chemspec^®is a qualified manufacturer and supplier which audited and approved by SGS and ISO,we are strictly following the Quality Management System ISO9001:2015.

In response to the call for national industry-university-research collaborative innovation,to promot high-quality development through innovation and fostering new growth drivers.YR Chemspec^®is raising its capacity for pursuing scientific and technological innovation via cooperating with the famous Universities and Insititues.Main of our industry-university-research collaborative projects including,*Vitamin Derivatives,*Fermented Actives,*Plant extracts ,*PVP Polymers and Polyquaternium series products.

Thanks to our persistence on industry-university-research,we set up a broad range portfolio of chemical raw materials/ingredients,especially we get a huge improvement on personal care active ingredients,and approved by worldwide partners of our Ascorbyl Tetraisopalmitate,Ethyl Ascobic Acid,Magensium Ascorbyl Phosphate,Sodium Ascorbyl Phosphate,Hydroxypinacolone Retinoate, Bakuchiol,Resveratrol,Glutathione,Bisabolol,1,3-Dihydroxyacetone,Erythrulose and etc.

In virtue of the advantages of Industry-university-research collaboration.Over the past years development,YR Chemspec^® is growing up into an important player in the world market of cosmetic active ingredients and raw materials.

YR Chemspec^®is engaged in the production and distribution a broad range portfolio of specialty,raw materials,active ingredients for the global cosmetic/personal care industries.We are always dedicated in state-of-the-art technology innovations, manufacturing process,distributing,sourcing high quality raw materials and ingredients,and providing 7*24 hours response and service for our global partners.Our mission is to help all of our partners to get exceptional products for using in their formulations,and keep assure all ingredients/raw materials are safe,healthy,stable supplying with competitive price and on time service.

Cosmetic formulation design is a comprehensive technology,it involves knowledge in a variety of fields,including Chemistry,Biology,Aesthetics and so on.Cosmetic formulators have to always take into account both safety and effectiveness of

cosmetic products.In the formulation design process,product development managers need to consider the various ingredients that may be used, as well as all ingredients’ founctions and the combination of those founctions,in order to ensure that they meet the needs of consumers and achieve the desired results.

The core principles of cosmetic formulation design are safety and efficacy, but the safety of cosmetic products is the most important,that designers should always pay attention to.The ingredients in cosmetics should be rigorously screened and tested to ensure that they are harmless to humans. Product development managers need to understand the properties and interactions of various ingredients to ensure that they can achieve the desired results.

The combination of active ingredients with different founctions is a crucial part of the formulation design of cosmetics. Different ingredients have different founctions, and their combination can only enhance the efficacy of the product if it creates a collaborative efficacy. Product development requires careful selection and matching of ingredients to ensure they work best with each other.Product development should also take into account the stability and texture of the product. Cosmetics need to be stable during use and not affected by the external environment. To achieve this, all ingredients should be high stable,and the suppliers should be reliable.

YR Chemspec^®is the active & professional team providing cosmetic raw materials and active ingredients in beauty filed.We are always trying to offer the best quality with reasonable price.We strongly believe that proper personal care product begins with the right ingredients selection,providing the right ingredients to our partners is our key priority.

YR Chemspec^®isn’t just a raw materials,ingredients supplier,we are your loyal partner.We not only dispatch products,but with our reputation,promise,service and added value to the global corner.To help our partners save the paying on costs,time and reduce the risks to consider any new suppliers,we also well provide a package products service and sourcing service from China.

YR Chemspec^®is always committed to implement the strategy of substainable development, focused on the harmony of human and nature for striving to creat civilized developing way.

Inquiry History

86 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	Competitive Price CAS 98-92-0 Vitamin B3 Niacinamide 99% white powder 98-92-0	100 KG	Sep 23, 2023
India	Nicotinamide	45.00 KG	Jun 13, 2025
India	Nicotinamide	25.00 KG	Jun 12, 2025
India	Nicotinamide	50.00 KG	Jun 11, 2025
India	Nicotinamide	50.00 KG	Jun 13, 2025
United States	Niacinamide	1 KG	Feb 5, 2024
India	Nicotinamide	25.00 KG	Jun 11, 2025
Russia	Niacinamide	1 KG	Dec 2, 2024
India	Niacinamide	1.00 KG	Jun 1, 2026
Nigeria	Niacinamide	100.00 KG	May 25, 2026
United States	Nicotinamide	20 MG	May 25, 2026
India	Nicotinamide	500 KG	Apr 28, 2026
India	Niacinamide	100.00 KG	Apr 13, 2026
Pakistan	NICOTINAMIDE	375 KG	Apr 10, 2026
India	Niacinamide	1.00 KG	Apr 10, 2026
Brazil	Nicotinamide	550 G	Mar 13, 2026
Malawi	Niacinamide	1 KG	Mar 2, 2026
Germany	Nicotinamide	1000 G	Feb 25, 2026
India	Niacinamide	1.00 KG	Feb 10, 2026
India	Niacinamide	500.00 KG	Feb 6, 2026

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100% Original China Nicotinamide Vitamin B3 CAS 98-92-0

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