Guanfacine HCl CAS No.29110-48-3
GMP ISO FDA 9 Inquiries
29110-48-3
Pharmaceutical grade
99%
Shanghai
JINLAN PHARM
25Kg/drum
2022-12-31
additives,pharmaceutical chemicals,organic intermediate,chemical intermediates,Pharmaceutical Intermediates,catalyst
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceGuanfacine Hcl, an anti-hypertensive agent, is a selective α2A-adrenoceptor agonist with Kd of 31 nM and displays 60-fold selectivity over α2B-adrenoceptors. IC50 Value: 31 nM(Kd)Target: Adrenergic ReceptorGuanfacine is a sympatholytic. It is a selective α2A receptor agonist. These receptors are concentrated heavily in the prefrontal cortex and the locus coeruleus, with the potential to improve attention resulting from interaction with receptors in the former. Guanfacine lowers both syst
Guanfacine hydrochloride is a member of acetamides. It has a role as a geroprotector.|Guanfacine Hydrochloride is the hydrochloride salt form of guanfacine, a centrally acting alpha-2 adrenergic agonist with antihypertensive activity. Alpha-2 receptor stimulation by guanfacine hydrochloride results in a decreased sympathetic outflow from the vasomotor center to the heart, kidneys, and peripheral vasculature. This leads to a decrease in heart rate and peripheral vascular resistance. (NCI05)|A centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.
ChEBI: Guanfacine hydrochloride is a member of acetamides. It has a role as a geroprotector.
Guanfacine hydrochloride,N-(aminoiminomethyl)-2,6-dichlorobenzeneacetamide(Tenex), is structurally related to clonidine hydrochloride andguanabenz acetate and shares many of their pharmacologicalproperties. The drug has a longer duration of action than eitherclonidine hydrochloride or guanabenz acetate. It lasts upto 24 hours. It also requires much longer (8–12 hours) for apeak effect to occur after the drug is administered.CertificatesBasic Info-
Product Name:
GUANFACINE HCL
Other Name:bs100-141;estulic;lon798;n-(aminoiminomethyl)-2,6-dichlorobenzeneacetamidehydrochloride;n-(aminoiminomethyl)-2,6-dichloro-benzeneacetamidmonohydrochloride;n-amidino-2-(2,6-dichlorophenyl)acetamidehydrochloride;N (AMINOIMINOMETHYL)-2,6-DICHLOROBENZENEACETAMIDE HYDROCHLORIDE SALT;[(2,6-DICHLOROPHENYL)ACETYL]GUANIDINE HYDROCHLORIDE
CAS No.:29110-48-3
Molecular Formula:C9H9Cl2N3O.ClH
InChIKeys:DGFYECXYGUIODH-UHFFFAOYSA-N
Molecular Weight:282.55
Exact Mass:280.988953
EC Number:249-443-3
UNII:PML56A160O
NSC Number:759121
DSSTox ID:DTXSID2045157
NCI Thesaurus Code:C47550
Color/Form:white
ATC Code:C02AC02
HScode:2925294500
Categories:
Characteristics-
PSA:
81.5
XLogP3:3.53850
Appearance:white
Melting Point:215-217℃
Water Solubility:H2O: soluble 12mg/mL at60°C
Storage Conditions:Store at RT
Toxicity:LD50 in mice: 165 mg/kg orally (Coward)
Critical Temperature & Pressure:Inert atmosphere,Room Temperature
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 3, Oral
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H301 Toxic if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
additives,pharmaceutical chemicals,organic intermediate,chemical intermediates,Pharmaceutical Intermediates,catalyst
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Location:
hangzhou,zhejiang
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
30
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
11-50
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Year of Establishment:
2020
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Inquiry History9 Inquiries
Country Product Purchase Quantity Date Posted 
Greece
GUANFACINE HCL 98% white powder
500 MG May 1, 2026 
United States
guanfacine hydrochloride
1 G Apr 13, 2026 
Bangladesh
Guanfacine Hydrochloride
1 KG Mar 10, 2026 
United Kingdom
Guanfacine HCL
2 G May 11, 2024 
Russia
n-(aminoiminomethyl)-2,6-dichloro-benzeneacetamidmonohydrochloride
160 MT Jun 22, 2026
Greece
Guanfacine HCl
500 MG Apr 30, 2026
United States
Guanfacine hydrochloride
1 G Oct 25, 2025
United States
GUANFACINE HCL
2 G Oct 6, 2025 
South Korea
Donephezil
100 MG Jul 2, 2024 Post an enquiry for this product
