Leucine dehydrogenase from Microorganism
9082-71-7
Yes
2026-11-15
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Leucine dehydrogenase from Microorganism Cat No NATE-1715 Description In enzymology, a leucine dehydrogenase (EC 1.4.1.9) is an enzyme that catalyzes the chemical reaction: L-leucine + H2O + NAD+ ↔ 4-methyl-2-oxopentanoate + NH3 + NADH + H+. The 3 substrates of this enzyme are L-leucine, H2O, and NAD+, whereas its 4 products are 4-methyl-2-oxopentanoate, NH3, NADH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. This enzyme participates in valine, leucine and isoleucine degradation and valine, leucine and isoleucine biosynthesis. Abbr LEDH (Microorganism) Source Microorganism Form White powder, lyophilized Enzyme Commission Number EC 1.4.1.9 Activity >500U/mg protein CAS No 9082-71-7 Molecular Weight 43 kDa (SDS-PAGE) Isoelectric point 6.6 pH Stability 6.0~11.0 (25℃, 15hr) Michaelis Constant 2.6×10^-4 M (NAD )2.0×10^-3 M(L-Leucine)6.8×10^-4 M(α-Ketoisocaproate)4.2×10^-2 M (NH Cl)2.3×10^-4 M (NADH) Unit Definition One unit will convert one micromole of L-Leucine to α-Ketoisocaproate per minute at pH 10.5 at 37℃. Optimum pH above11.0(L-Leu→α-K I C),8.5(α-K I C→L-Leu) Optimum temperature 55-60℃(L-Leu →α-K I C)above 60℃(α-K I C→L-Leu) Thermal stability < 55℃(pH 7.0, 20min) Storage Store at -20°C. Inhibitors Hg2+ Synonyms EC 1.4.1.9; Leucine dehydrogenase; L-leucine: NAD+ oxidoreductase (deaminating); L-leucine dehydrogenase; L-leucine: NAD+ oxidoreductase (deaminating); LeuDH Notes INTENDED FOR RESEARCH USE ONLY, NOT FOR USE IN HUMAN, THERAPEUTIC OR DIAGNOSTIC APPLICATIONS. category Amino Acids and Derivatives(c1517) cas_num 9082-71-7 ECHEMI Editorial ReferencePowderBasic Info-
Product Name:
Leucine dehydrogenase
Other Name:Leucine dehydrogenase;Dehydrogenase,leucine;E.C. 1.4.1.9;L-Leucine dehydrogenase;EC 1.4.1.9;Valine/leucine dehydrogenase;L-Leucine dehydrogenases;Valine/leucine dehydrogenases;Leucine dehydrogenases;L-Leucine dehydrogenases;L-Leucine dehydrogenase;1: PN: CN108103038 SEQID: 3 claimed sequence
CAS No.:9082-71-7
HScode:35079090
Categories:
Characteristics-
Appearance:
slightly brown solution
Storage Conditions:−20°C
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
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Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15 days
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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