Native Bacillus fastidiosus Uricase
2 Inquiries
9002-12-4
2026-10-02
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Inquiry History
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Description
ProductName Native Bacillus fastidiosus Uricase Cat No DIA-173 Description The enzyme urate oxidase (UO), or uricase or factor-independent urate hydroxylase, absent in humans, catalyzes the oxidation of uric acid to 5-hydroxyisourate: Uric acid + O2 + H2O → 5-hydroxyisourate + H2O2 → allantoin + CO2 Abbr UO (Bacillus fastidiosus) Alias UO; uricase Source Bacillus fastidiosus Appearance White to off-white powder Product Overview Urate:oxygen oxidoreductase produced in microorganism has a molecular mass of approximately 34 kDa. Form Freeze dried powder Enzyme Commission Number EC 1.7.3.3 Activity 15 U/mg CAS No 9002-12-4 Contaminants Cholesterol oxidase < 0.005%; Catalase < 1%; Glucose oxidase < 0.005% pH Stability 5.5-10.0 (25°C for 20 hrs) Unit Definition One unit will oxidize one micromole of uric acid at pH8.5 at 25°C. Optimum pH 7 Optimum temperature 37°C Thermal stability Stable at 50°C and below (pH 7.0, 15 mins) Storage -20°C Inhibitors Ag+, Hg2+ Synonyms urate oxidase; uric acid oxidase; uricase; uricase; urate: oxygen oxidoreductase; EC 1.7.3.3; uricase II; UO category Antipyretic Analgesics(c1413) cas_num 9002-12-4 ECHEMI Editorial ReferenceWhite powder
Mice deficient in uricase develop uric acid nephropathy and diabetes insipidus which can be mitigated with recombinant uricase treatment.
Urate Oxidase Recombinant produced in E.Coli is a tetrameric, non-glycosylated polypeptide chain containing 302 amino acids, having a molecular formula of C1523H2383N417O462S7 and a molecular mass of 34,247 Dalton.The cDNA coding for urate-oxidase was cloned from a strain of Aspergillus flavus . The monomer protein has no intra- or inter-disulfide bridges.
Escherichia ColiBasic Info-
Product Name:
URICASE
Other Name:EC 1.7.3.3;EC: 1.7.3.3;IUB: 1.7.3.3;URATE: O2 OXIDOREDUCTASE;URATE OXIDASE;URATE: OXIDOREDUCTASE;URATE: OXYGEN OXIDOREDUCTASE;URATE: OXYGEN OXOREDUCTASE
CAS No.:9002-12-4
Molecular Formula:C18H26N5O14P
InChIKeys:VPXDHZMLJOJKOX-UHFFFAOYSA-N
Molecular Weight:567.397901
Exact Mass:567.121399
EC Number:232-655-5
TSCA:TSCA listed
DSSTox ID:DTXSID8046826
Color/Form:White to off-white
HScode:35079090
Categories:
Characteristics-
PSA:
255
Appearance:lyophilized powder
Water Solubility:Hardly soluble in water, slightly soluble in buffer alkaline solution.
Storage Conditions:−20°C
Critical Temperature & Pressure:-20°C
Hazard IdentificationClassification of the substance or mixture
Not classified.
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Precautionary statement(s) Prevention none
Response none
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted 
United Kingdom
Uricase
28 MG Feb 5, 2025 
United States
Uricase enzyme
1 G Feb 8, 2024 Post an enquiry for this product