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Urate oxidase

Urate oxidase structure

CAS No:
9002-12-4
Chemical Name:
Urate oxidase
Synonyms:
Urate oxidase;Oxidase,urate;E.C. 1.7.3.3;Uricase;E. C. 1.7.3.3;Uric acid oxidase;Urate:O2-oxidoreductase;Uratoxidase;Uricozyme
Categories:
Active Pharmaceutical Ingredients > Antipyretic Analgesics

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Description

White powder

Urate oxidase Basic Attributes

Molecular Weight：

567.401

Exact Mass：

567.121399

EC Number：

232-655-5

DSSTox ID：

DTXSID8046826

HScode：

35079090

Characteristics

PSA：

255

Appearance：

lyophilized powder

Water Solubility：

Hardly soluble in water, slightly soluble in buffer alkaline solution.

Storage Conditions：

−20°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

safety instructions：

24/25

RTECS Number：

YU7100000

Precautionary statement(s)：

P201-P261-P280-P284-P304 + P340-P308 + P313

Hazard Statements：

H334-H360FD

GHS Classification：

|Danger|H334 (100%): May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]|P261, P285, P304+P341, P342+P311, and P501|Aggregated GHS information provided by 2 companies from 2 notifications to the ECHA C&L Inventory.

Urate oxidase Use and Manufacturing

Methods of Manufacturing

Using yeast as raw material, the sodium phosphate is extracted and then graded with ammonium sulfate, and then the product is obtained by dialysis, column chromatography and ammonium sulfate recrystallization.

Uses

In the determination of serum and urine uric acid.

Manufacturing Info：

Urate oxidase: ACTIVE|XU - indicates a substance exempt from reporting under the Chemical Data Reporting Rule, (40 CFR 711).

Computed Properties

Molecular Weight:567.4
Hydrogen Bond Donor Count:8
Hydrogen Bond Acceptor Count:15
Rotatable Bond Count:8
Exact Mass:567.12138752
Monoisotopic Mass:567.12138752
Topological Polar Surface Area:255
Heavy Atom Count:38
Complexity:1070
Undefined Atom Stereocenter Count:8
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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